Nemonoxacin

Generic Name: Nemonoxacin

Drug Type: Small Molecule

Chemical Formula: C_₂₀H_₂₅N_₃O_₄

CAS Number: 378746-64-6

Unique Ingredient Identifier: P94L0PVO94

Indication: Investigated for use/treatment in bacterial infection and pneumonia.

Clinical Trials

Oral Nemonoxacin in Treating Elderly Patients With CAP

Phase 4

Completed

Conditions: Community-acquired Pneumonia

Interventions: Drug: Nemonoxacin

First Posted Date: 2021-11-24

Last Posted Date: 2021-11-24

Lead Sponsor: TaiGen Biotechnology Co., Ltd.

Target Recruit Count: 100

Registration Number: NCT05133752

Locations: 🇨🇳
Tri-Service General Hospital, Taipei, Taiwan

Efficacy and Safety of Nemonoxacin vs Levofloxacin in Adult Patients With Community-Acquired Pneumonia

Phase 3

Completed

Conditions: Pneumonia, Bacterial

Interventions: Drug: Tavanic
Drug: Nemonoxacin
Drug: Placebo (250 ml)
Drug: Placebo (100 ml)

First Posted Date: 2018-06-11

Last Posted Date: 2023-02-16

Lead Sponsor: R-Pharm

Target Recruit Count: 342

Registration Number: NCT03551210

Locations: 🇷🇺
City clinical hospital #40, Ekaterinburg, Russian Federation
🇷🇺
Regional budget healthcare institution "Ivanovo regional clinical hospital", Ivanovo, Russian Federation
🇷🇺
City Clinical hospital n.a. V. V. Vinogradov, Moscow, Russian Federation

and more 22 locations

A Study Evaluating the Effect of a Single-dose Oral Administration of Nemonoxacin Capsule on QTc Intervals and Heart Rhythms of Healthy Subjects and the Influence of Food Intake on QTc Intervals and Pharmacokinetic Characteristics

Phase 1

Completed

Conditions: Healthy Volunteers

Interventions: Drug: Nemonoxacin 500Mg Capsule
Drug: Moxifloxacin 400Mg Tablet
Drug: Nemonoxacin 750Mg Capsule
Drug: Placebo oral capsule

First Posted Date: 2017-12-05

Last Posted Date: 2017-12-06

Lead Sponsor: TaiGen Biotechnology Co., Ltd.

Target Recruit Count: 48

Registration Number: NCT03362853

Pharmacokinetics Study of Nemonoxacin Malate Capsules in Subjects With Severe Impaired Renal Function

Phase 1

Conditions: Kidney Dysfunction

Interventions: Drug: Nemonoxacin

First Posted Date: 2016-07-21

Last Posted Date: 2018-04-03

Lead Sponsor: Zhejiang Medicine Co., Ltd.

Target Recruit Count: 24

Registration Number: NCT02840812

Locations: 🇨🇳
ZheJiang Medicine, Shaoxing, China

Pharmacokinetics Study of Nemonoxacin Malate Capsules in Subjects With Moderate Impaired Hepatic Function

Phase 1

Completed

Conditions: Liver Dysfunction

Interventions: Drug: Nemonoxacin

First Posted Date: 2015-11-13

Last Posted Date: 2018-03-30

Lead Sponsor: Zhejiang Medicine Co., Ltd.

Target Recruit Count: 20

Registration Number: NCT02604498

Locations: 🇨🇳
Huashan Hospital, Fudan University, Shanghai, Shanghai, China

A Phase III Study to Evaluate the Efficacy and Safety of Intravenous Infusion of Nemonoxacin in Treating CAP

Phase 3

Completed

Conditions: Community-acquired Pneumonia

Interventions: Drug: Nemonoxacin
Drug: Levofloxacin

First Posted Date: 2014-07-31

Last Posted Date: 2021-10-25

Lead Sponsor: TaiGen Biotechnology Co., Ltd.

Target Recruit Count: 598

Registration Number: NCT02205112

Locations: 🇨🇳
Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
🇨🇳
Kaohsiung Medical University Chung-Ho Memorial Hospital, Kaohsiung, Taiwan
🇨🇳
Taipei Medical University - Shuang Ho Hospital, Taipei, Taiwan

and more 60 locations

Study to Evaluate the Efficacy and Safety of Intravenous Infusion With Nemonoxacin Malate Sodium Chloride

Phase 2

Completed

Conditions: Pneumonia

Interventions: Drug: Nemonoxacin 500 mg
Drug: Moxifloxacin 400 mg
Drug: Nemonoxacin 650 mg

First Posted Date: 2013-09-18

Last Posted Date: 2015-02-18

Lead Sponsor: TaiGen Biotechnology Co., Ltd.

Target Recruit Count: 207

Registration Number: NCT01944774

Locations: 🇨🇳
Institute of Antibiotics, Huashan Hospital, Fundan University, Shanghai, China
🇨🇳
Far eastern memorial hospital, Taipei, Taiwan

Phase II Clinical Study to Assess the Efficacy and Safety of Nemonoxacin Malate in Treating Adult Patients With Community-acquired Pneumonia (CAP)

Phase 2

Completed

Conditions: Community-acquired Pneumonia

Interventions: Drug: Levofloxacin 500 mg placebol
Drug: Nemonoxacin 3 tablets

First Posted Date: 2012-02-23

Last Posted Date: 2018-01-24

Lead Sponsor: TaiGen Biotechnology Co., Ltd.

Target Recruit Count: 192

Registration Number: NCT01537250

Locations: 🇨🇳
Beijing Chaoyang Hospital, Capital Medical University, Beijing, China
🇨🇳
Beijing Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
🇨🇳
Peking University First Hospital, Beijing, China

and more 29 locations

A Study of Nemonoxacin Malate Sodium Chloride Injection Administered by Intravenous Infusion

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: Nemonoxacin Malate Sodium Chloride

First Posted Date: 2012-02-09

Last Posted Date: 2012-02-20

Lead Sponsor: TaiGen Biotechnology Co., Ltd.

Target Recruit Count: 176

Registration Number: NCT01529957

Locations: 🇨🇳
Guangzhou Red Cross Hospital, Guangzhou, China
🇨🇳
Third Military Medical University, Third Affiliated Hospital, Chongqing, China
🇨🇳
Zhen Hospital, Capital Medical University Beijing, Beijing, China

and more 23 locations

Study to Evaluate the Efficacy and Safety of Oral Administration With Nemonoxacin and Levofloxacin in Patients With CAP

Phase 3

Completed

Conditions: Pneumonia

Interventions: Drug: Nemonoxacin
Drug: Levofloxacin

First Posted Date: 2012-02-08

Last Posted Date: 2013-06-18

Lead Sponsor: TaiGen Biotechnology Co., Ltd.

Target Recruit Count: 540

Registration Number: NCT01529476

Locations: 🇨🇳
Beijing Union Medical College Hospital, Beijing, China
🇨🇳
China Medical University Hospital, Taichung, Taiwan
🇨🇳
Anzhen Hospital,Beijing Capital Medical University, Anzhen, China

and more 54 locations

Drug Development Updates

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