Glutathione
- Generic Name
- Glutathione
- Drug Type
- Small Molecule
- Chemical Formula
- C10H17N3O6S
- CAS Number
- 70-18-8
- Unique Ingredient Identifier
- GAN16C9B8O
- Background
A tripeptide with many roles in cells. It conjugates to drugs to make them more soluble for excretion, is a cofactor for some enzymes, is involved in protein disulfide bond rearrangement and reduces peroxides.
- Indication
For nutritional supplementation, also for treating dietary shortage or imbalance
- Associated Conditions
- Hangover, Nerve Disorders, Neuropathy
Glucocorticoids for Acute Drug Induced Liver Injury With Hyperbilirubinemia
- Conditions
- Drug Induced Liver Injury
- Interventions
- Procedure: Plaslna exchangeProcedure: Liver transplantation
- First Posted Date
- 2025-04-10
- Last Posted Date
- 2025-04-10
- Lead Sponsor
- General Hospital of Shenyang Military Region
- Target Recruit Count
- 232
- Registration Number
- NCT06922669
- Locations
- 🇨🇳
Department of Gastroenterology, General Hospital of Northern Theater Command (formerly called General Hospital of Shenyang Military Area), Shenyang, Liaoning, China
Randomized Trial of Glutathione with Anti-PD-1 and Chemotherapy in Advanced NSCLC
- Conditions
- Non-Small Cell Lung CancerChemotherapyPD1 AntibodyGlutathione
- Interventions
- First Posted Date
- 2025-03-26
- Last Posted Date
- 2025-03-30
- Lead Sponsor
- The First Affiliated Hospital of Zhengzhou University
- Target Recruit Count
- 80
- Registration Number
- NCT06896422
- Locations
- 🇨🇳
the First Affiliated Hospital of Zhengzhou University, ZhengZhou, Henan, China
A Study of Glutathione in Children With Autism Spectrum Disorder
- First Posted Date
- 2023-07-20
- Last Posted Date
- 2023-08-23
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 6
- Registration Number
- NCT05954052
- Locations
- 🇺🇸
The University of Chicago Medicine, Chicago, Illinois, United States
Oral Glutathione As A Skin Whitening Agent
- Conditions
- GlutathioneSkin Whitening
- Interventions
- Drug: Placebo oral tablet
- First Posted Date
- 2019-09-26
- Last Posted Date
- 2019-09-26
- Lead Sponsor
- Dr Irma Bernadette S Sitohang
- Target Recruit Count
- 90
- Registration Number
- NCT04105504
- Locations
- 🇮🇩
Faculty of Medicine, Universitas Indonesia, Jakarta Pusat, Indonesia
The Role of Oral Glutathione on Growth Parameters in Children With Cystic Fibrosis
- First Posted Date
- 2017-01-13
- Last Posted Date
- 2020-01-09
- Lead Sponsor
- University of Minnesota
- Target Recruit Count
- 60
- Registration Number
- NCT03020719
- Locations
- 🇺🇸
The University of Vermont Inc., Burlington, Vermont, United States
🇺🇸Nemours Childrens Clinic, Jacksonville, Florida, United States
🇺🇸Connecticut Childrens Medical Center, Hartford, Connecticut, United States
Glutathione vs. Curcumin Clinical Trial
- First Posted Date
- 2016-07-28
- Last Posted Date
- 2020-01-29
- Lead Sponsor
- South Florida Veterans Affairs Foundation for Research and Education
- Target Recruit Count
- 75
- Registration Number
- NCT02848417
- Locations
- 🇺🇸
Miami VA Center, Miami, Florida, United States
Dual Hypothermic Oxygenated Perfusion of DCD Liver Grafts in Preventing Biliary Complications After Transplantation
- Conditions
- Liver FailureBiliary Tract DiseasesEnd Stage Liver Disease
- Interventions
- Procedure: Dual hypothermic oxygenated perfusionDevice: Liver Assist®Procedure: Perfusion fluid
- First Posted Date
- 2015-10-22
- Last Posted Date
- 2021-01-12
- Lead Sponsor
- Robert J. Porte
- Target Recruit Count
- 157
- Registration Number
- NCT02584283
- Locations
- 🇧🇪
Ghent University Hospital, Gent, De Pintelaan 185, Belgium
🇳🇱Leiden Universtiy Medical Center, Leiden, Zuid-Holland, Netherlands
🇧🇪University Hospitals Leuven, Leuven, Herestraat 49, Belgium
Phase IIb Study of Intranasal Glutathione in Parkinson's Disease
- Conditions
- Parkinson's Disease
- Interventions
- First Posted Date
- 2015-04-23
- Last Posted Date
- 2016-06-24
- Lead Sponsor
- Bastyr University
- Target Recruit Count
- 45
- Registration Number
- NCT02424708
- Locations
- 🇺🇸
Bastyr University, Kenmore, Washington, United States
🇺🇸University of Washington, Seattle, Washington, United States
CNS Uptake of Intranasal Glutathione
- First Posted Date
- 2014-12-24
- Last Posted Date
- 2015-04-30
- Lead Sponsor
- University of Washington
- Target Recruit Count
- 15
- Registration Number
- NCT02324426
- Locations
- 🇺🇸
University of Washington, Seattle, Washington, United States
Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer
- Conditions
- Chemotherapeutic Agent ToxicityNeuropathyNeurotoxicity SyndromePainStage IIIA Fallopian Tube CancerStage IIIA Ovarian CancerStage IIIA Primary Peritoneal CancerStage IIIB Fallopian Tube CancerStage IIIB Primary Peritoneal CancerStage IIIB Ovarian Cancer
- Interventions
- Other: Laboratory Biomarker AnalysisOther: PlaceboOther: Quality-of-Life Assessment
- First Posted Date
- 2014-12-09
- Last Posted Date
- 2017-02-23
- Lead Sponsor
- Alliance for Clinical Trials in Oncology
- Target Recruit Count
- 195
- Registration Number
- NCT02311907
- Locations
- 🇺🇸
Northside Hospital, Atlanta, Georgia, United States
🇺🇸Saint Joseph's Hospital of Atlanta, Atlanta, Georgia, United States
🇺🇸Pennsylvania Hospital, Philadelphia, Pennsylvania, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.