Ketorolac
- Generic Name
- Ketorolac
- Brand Names
- Acular, Acuvail, Omidria, Readysharp Anesthetics Plus Ketorolac, Sprix, Toradol, Toronova Suik
- Drug Type
- Small Molecule
- Chemical Formula
- C15H13NO3
- CAS Number
- 74103-06-3
- Unique Ingredient Identifier
- YZI5105V0L
- Background
Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.
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- Indication
Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and has antipyretic, analgesic and anti-inflammatory properties. It is indicated for short term management of acute pain that requires the calibre of pain management offered by opioids. Clinicians may choose to initiate ketorolac to manage post-operative pain, spinal and soft tissue pain, rheumatoid...
- Associated Conditions
- Acute Migraine, Eye Pain, Inflammation, Macular Edema, Cystoid, Ocular Itching, Pericarditis Acute, Pseudophakic Cystoid Macular Oedema, Severe Acute Pain, Acute, moderate Pain, Chronic aphakic cystoid macular edema, Intraoperative miosis, Postoperative ocular pain
- Associated Therapies
- -
Efficacy, Safety and Tolerability Study of N1539 in Subjects After Abdominal Laparoscopic Surgery
- Conditions
- Interventions
- First Posted Date
- 2011-09-19
- Last Posted Date
- 2012-03-14
- Lead Sponsor
- Alkermes, Inc.
- Target Recruit Count
- 50
- Registration Number
- NCT01436032
- Locations
- 🇺🇸
Lotus Clinical Research LLC, Pasadena, California, United States
Safety and Pharmacokinetics Study of Intranasal Ketorolac in Elderly and Nonelderly Adult Healthy Subjects
- First Posted Date
- 2011-06-03
- Last Posted Date
- 2013-02-06
- Lead Sponsor
- American Regent, Inc.
- Target Recruit Count
- 30
- Registration Number
- NCT01365624
- Locations
- 🇺🇸
Seaview Research, Miami, Florida, United States
Open Label Study to Assess the Pharmacokinetics of Intranasal Ketorolac Tromethamine Following Fluticasone Propionate in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2011-06-03
- Last Posted Date
- 2017-03-15
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 36
- Registration Number
- NCT01365611
- Locations
- 🇬🇧
ICON Development Solutions, Manchester, United Kingdom
Study to Assess the Absorption and Tolerability of Intranasal Ketorolac Tromethamine and to Assess the Effects of Oxymetazoline Hydrochloride and Fluticasone Propionate on the Absorption and Tolerability of Intranasal Ketorolac Tromethamine in Participants With Allergic Rhinitis
- Conditions
- Interventions
- First Posted Date
- 2011-06-03
- Last Posted Date
- 2018-03-06
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 24
- Registration Number
- NCT01365650
- Locations
- 🇦🇺
Pain and Anaesthesia Research Clinic/Royal Adelaide Hospital, Adelaide, Australia
Study to Assess the PK of Ketorolac Tromethamine Intranasal and to Assess the Effects of a Oxymetazoline Hydrochloride on the PK of Ketorolac Tromethamine
- First Posted Date
- 2011-06-01
- Last Posted Date
- 2017-02-09
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 21
- Registration Number
- NCT01363089
- Locations
- 🇬🇧
ICON Development Solutions, Manchester, United Kingdom
The Pharmacokinetics of Ketorolac Tromethamine Administered Intranasally (IN) for Postoperative Pain in Children Aged 12 Through 17 Years
- First Posted Date
- 2011-06-01
- Last Posted Date
- 2017-03-16
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 20
- Registration Number
- NCT01363076
- Locations
- 🇺🇸
Stanford University Medical Center, Stanford, California, United States
Study to Determine the Tolerability, Safety and Pharmacokinetics of Ketorolac Tromethamine by Intranasal Administration in Healthy Volunteers
- First Posted Date
- 2011-06-01
- Last Posted Date
- 2017-03-16
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 15
- Registration Number
- NCT01363050
- Locations
- 🇬🇧
Medeval Limited, Manchester, United Kingdom
Study of the Tolerability of Ketorolac Tromethamine Following Intranasal Administration in Healthy Volunteers
- First Posted Date
- 2011-06-01
- Last Posted Date
- 2018-03-06
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 40
- Registration Number
- NCT01363063
- Locations
- 🇬🇧
ICON Developmental Solutions, Manchester, United Kingdom
Assessment of Nasal Deposition and Clearance of Ketorolac Solution Administered Using the Valois Nasal Spray Device
- First Posted Date
- 2011-05-19
- Last Posted Date
- 2017-02-08
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 13
- Registration Number
- NCT01356212
- Locations
- 🇬🇧
Pharmaceutical Profiles, Ltd, Ruddington, Nottingham, United Kingdom
A Single-dose Study of Intranasal Ketorolac in the Treatment of Pain Secondary to Dental Impaction Surgery
- Conditions
- Interventions
- First Posted Date
- 2011-05-19
- Last Posted Date
- 2017-02-09
- Lead Sponsor
- Egalet Ltd
- Target Recruit Count
- 80
- Registration Number
- NCT01356225
- Locations
- 🇺🇸
Austin Oral Surgery - PPD Development, Austin, Texas, United States
Drug Development Updates
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