Ketorolac

Generic Name
Ketorolac
Brand Names
Acular, Acuvail, Omidria, Readysharp Anesthetics Plus Ketorolac, Sprix, Toradol, Toronova Suik
Drug Type
Small Molecule
Chemical Formula
C15H13NO3
CAS Number
74103-06-3
Unique Ingredient Identifier
YZI5105V0L
Background

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and is commercially available as an oral tablet, injectable, nasal spray and as an ophthalmic solution.
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Indication

Ketorolac is a Non-steroidal anti-inflammatory drug (NSAID) and has antipyretic, analgesic and anti-inflammatory properties. It is indicated for short term management of acute pain that requires the calibre of pain management offered by opioids. Clinicians may choose to initiate ketorolac to manage post-operative pain, spinal and soft tissue pain, rheumatoid...

Associated Conditions
Acute Migraine, Eye Pain, Inflammation, Macular Edema, Cystoid, Ocular Itching, Pericarditis Acute, Pseudophakic Cystoid Macular Oedema, Severe Acute Pain, Acute, moderate Pain, Chronic aphakic cystoid macular edema, Intraoperative miosis, Postoperative ocular pain
Associated Therapies
-
Clinical Trials
Related News

Intranasal Ketorolac Tromethamine (Sprix) for Acute Pain of Interstitial Cystitis Flare of Pain

Phase 4
Completed
Conditions
Interstitial Cystitis
Interventions
Drug: Ketorolac Tromethamine
First Posted Date
2013-12-04
Last Posted Date
2013-12-04
Lead Sponsor
Citrus Valley Medical Research, Inc.
Target Recruit Count
15
Registration Number
NCT02000401
Locations
🇺🇸

Citrus Valley Medical Research, Inc, Glendora, California, United States

Intranasal Ketorolac Tromethamine (SPRIX) as a Short Term Pain Management of Post-Vasectomy Pain

First Posted Date
2013-12-04
Last Posted Date
2013-12-04
Lead Sponsor
Citrus Valley Medical Research, Inc.
Target Recruit Count
15
Registration Number
NCT02000388

Efficacy of Intravenous Ibuprofen Compared to Intravenous Ketorolac for Pain Control Following Arthroscopic Knee Surgery

Phase 4
Completed
Conditions
Pain
Interventions
Drug: IV ibuprofen
Drug: Ketorolac
First Posted Date
2013-07-17
Last Posted Date
2016-03-14
Lead Sponsor
Cumberland Pharmaceuticals
Target Recruit Count
100
Registration Number
NCT01901393
Locations
🇺🇸

Shrock Orthopedic Research, Fort Lauderdale, Florida, United States

🇺🇸

Rush University Medical Center, Chicago, Illinois, United States

🇺🇸

North Mississippi Sports Medicine & Orthopaedic Clinic, Tupelo, Mississippi, United States

and more 1 locations

Efficacy Parecoxib and Ketorolac as Preemptive Analgesia in Spine Fusion

Phase 4
Completed
Conditions
Postoperative Pain
Interventions
Drug: Parecoxib
Drug: Ketorolac
First Posted Date
2013-05-22
Last Posted Date
2013-05-22
Lead Sponsor
Prince of Songkla University
Target Recruit Count
96
Registration Number
NCT01859585
Locations
🇹🇭

Faculty of Medicine, Prince of Songkla University, Hadyai, Sonkla, Thailand

Protein Profile of Immunoregulatory Factors in Diabetic Cataract

Phase 4
Completed
Conditions
Cataract
Type 2 Diabetes Mellitus
Interventions
Drug: Ketorolac
First Posted Date
2013-04-16
Last Posted Date
2013-04-16
Lead Sponsor
University of Zagreb
Target Recruit Count
61
Registration Number
NCT01832311
Locations
🇭🇷

Department of Physiology and Immunology, University of Zagreb School of Medicine, Zagreb, Grad Zagreb, Croatia

🇭🇷

Department of Ophtalmology, General Hospital "Dr. J. Bencevic", Slavonski brod, Brodsko-posavska zupanija, Croatia

Comparison of Ketorolac Nasal Spray to Sumatriptan Nasal Spray and Placebo for Acute Treatment of Migraine

Phase 4
Completed
Conditions
Migraines
Interventions
Drug: Ketorolac
Drug: Sumatriptan
Drug: Placebo
First Posted Date
2013-03-08
Last Posted Date
2017-03-13
Lead Sponsor
Johns Hopkins University
Target Recruit Count
72
Registration Number
NCT01807234
Locations
🇺🇸

The Johns Hopkins Bayview Headache Center, Baltimore, Maryland, United States

Availability & Effect of Post-OP Ketorolac on Ovarian, Fallopian Tube or Primary Peritoneal Cancer

First Posted Date
2012-08-22
Last Posted Date
2020-02-27
Lead Sponsor
New Mexico Cancer Care Alliance
Target Recruit Count
29
Registration Number
NCT01670799
Locations
🇺🇸

University of New Mexico Cancer Center, Albuquerque, New Mexico, United States

The Use of Ketorolac in Surgical Neonates

First Posted Date
2012-08-17
Last Posted Date
2023-05-06
Lead Sponsor
Nationwide Children's Hospital
Target Recruit Count
6
Registration Number
NCT01667120
Locations
🇺🇸

Nationwide Children's Hospital, Columbus, Ohio, United States

Pain Control for Intrauterine Device Placement: A Trial of Ketorolac Prior to Intrauterine Device Placement

Not Applicable
Completed
Conditions
Pain Control With IUD Insertion
Interventions
Drug: Normal Saline
Drug: Ketorolac
First Posted Date
2012-08-14
Last Posted Date
2015-12-23
Lead Sponsor
Lynn Ngo
Target Recruit Count
67
Registration Number
NCT01664559
Locations
🇺🇸

University of California San Diego, San Diego, California, United States

Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival

First Posted Date
2012-07-13
Last Posted Date
2014-04-21
Lead Sponsor
Retina Vitreous Associates of Florida
Target Recruit Count
57
Registration Number
NCT01640171
Locations
🇺🇸

Retina Vitreous Associates of Florida, Clearwater, Florida, United States

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