Nitazoxanide
- Generic Name
- Nitazoxanide
- Brand Names
- Alinia, Busulfex
- Drug Type
- Small Molecule
- Chemical Formula
- C12H9N3O5S
- CAS Number
- 55981-09-4
- Unique Ingredient Identifier
- SOA12P041N
- Background
Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment o...
- Indication
用于治疗隐孢子虫、贾第鞭毛虫、阿米巴原虫引起的原虫性腹泻。
- Associated Conditions
- Diarrhea caused by Cryptosporidium parvum, Diarrhea caused by Giardia lamblia
- Associated Therapies
- -
Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Colds Due to Enterovirus/Rhinovirus Infection
- Conditions
- Interventions
- First Posted Date
- 2020-07-28
- Last Posted Date
- 2024-10-17
- Lead Sponsor
- Romark Laboratories L.C.
- Target Recruit Count
- 214
- Registration Number
- NCT04489381
- Locations
- 🇺🇸
HealthStar Research LLC, Hot Springs, Arkansas, United States
🇺🇸Invesclinic US LLC, Fort Lauderdale, Florida, United States
🇺🇸RH Medical Urgent Care, Bronx, New York, United States
Trial to Evaluate Efficacy and Safety of Nitazoxanide in the Treatment of Mild or Moderate COVID-19
- Conditions
- Interventions
- First Posted Date
- 2020-07-24
- Last Posted Date
- 2024-03-29
- Lead Sponsor
- Romark Laboratories L.C.
- Target Recruit Count
- 935
- Registration Number
- NCT04486313
- Locations
- 🇺🇸
Invesclinic US LLC, Fort Lauderdale, Florida, United States
🇺🇸RH Medical Urgent Care, Bronx, New York, United States
Efficacy and Safety Study of Nitazoxanide (NTX) in the Treatment of Patients With SARS-CoV-2 Virus Infection (COVID-19)
- First Posted Date
- 2020-07-09
- Last Posted Date
- 2020-10-08
- Lead Sponsor
- Laboratorios Roemmers S.A.I.C.F.
- Target Recruit Count
- 135
- Registration Number
- NCT04463264
- Locations
- 🇦🇷
Hospital Universitario Austral, Presidente Derqui, Buenos Aires, Argentina, Argentina
Efficacy and Safety of Nitazoxanide 600 mg to Treat Mild Ambulatory COVID-19 Patients
- First Posted Date
- 2020-06-22
- Last Posted Date
- 2022-10-28
- Lead Sponsor
- Azidus Brasil
- Registration Number
- NCT04441398
Efficacy and Safety of Nitazoxanide for Post Exposure Prophylaxis of COVID-19
- First Posted Date
- 2020-06-17
- Last Posted Date
- 2022-10-28
- Lead Sponsor
- Azidus Brasil
- Registration Number
- NCT04435314
Efficacy and Safety of Nitazoxanide 600 mg BID Versus Placebo for the Treatment of Hospitalized Patients With COVID-19
- First Posted Date
- 2020-06-09
- Last Posted Date
- 2022-10-31
- Lead Sponsor
- Azidus Brasil
- Target Recruit Count
- 380
- Registration Number
- NCT04423861
- Locations
- 🇧🇷
Hospital Vera Cruz, Campinas, São Paulo, Brazil
Study of Nitazoxanide (NTZ) for Helicobacter Pylori in Children
- Conditions
- Interventions
- First Posted Date
- 2020-06-04
- Last Posted Date
- 2020-06-04
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 100
- Registration Number
- NCT04415983
- Locations
- 🇪🇬
Sherief Abd-Elsalam, Tanta, Egypt
Novel Regimens in COVID-19 Treatment
- First Posted Date
- 2020-05-11
- Last Posted Date
- 2020-12-04
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 160
- Registration Number
- NCT04382846
- Locations
- 🇪🇬
Tanta University, Assiut University, Tanta, Egypt
🇪🇬Sherief Abd-Elsalam, Tanta, Egypt
Trial to Evaluate the Efficacy and Safety of Nitazoxanide (NTZ) for Pre- and Post Exposure Prophylaxis of COVID-19 and Other Viral Respiratory Illnesses (VRI) in Healthcare Workers and Others at Increased Risk of SARS-CoV-2 Infection
- Conditions
- Interventions
- First Posted Date
- 2020-04-24
- Last Posted Date
- 2024-06-26
- Lead Sponsor
- Romark Laboratories L.C.
- Target Recruit Count
- 1407
- Registration Number
- NCT04359680
- Locations
- 🇺🇸
The Chappel Group Research, Kissimmee, Florida, United States
🇺🇸Chicago Medical Research Institute, Inc., Chicago, Illinois, United States
🇺🇸Chicago Clinical Research Institute, Inc., Chicago, Illinois, United States
Trial to Evaluate the Efficacy and Safety of Nitazoxanide (NTZ) for Post-Exposure Prophylaxis of COVID-19 and Other Viral Respiratory Illnesses in Elderly Residents of Long-Term Care Facilities (LTCF)
- Conditions
- Interventions
- First Posted Date
- 2020-04-13
- Last Posted Date
- 2024-07-08
- Lead Sponsor
- Romark Laboratories L.C.
- Target Recruit Count
- 190
- Registration Number
- NCT04343248
- Locations
- 🇺🇸
The Chappel Group Research, Kissimmee, Florida, United States
🇺🇸Clinical Trial Specialists, Inc., Acworth, Georgia, United States
🇺🇸Centex Studies, Inc., Houston, Texas, United States
Drug Development Updates
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