Nitazoxanide

Generic Name
Nitazoxanide
Brand Names
Alinia, Busulfex
Drug Type
Small Molecule
Chemical Formula
C12H9N3O5S
CAS Number
55981-09-4
Unique Ingredient Identifier
SOA12P041N
Background

Nitazoxanide belongs to the class of drugs known as thiazolides. Nitazoxanide (NTZ) is a broad-spectrum anti-infective drug that markedly modulates the survival, growth, and proliferation of a range of extracellular and intracellular protozoa, helminths, anaerobic and microaerophilic bacteria, in addition to viruses. This drug is effective in the treatment o...

Indication

用于治疗隐孢子虫、贾第鞭毛虫、阿米巴原虫引起的原虫性腹泻。

Associated Conditions
Diarrhea caused by Cryptosporidium parvum, Diarrhea caused by Giardia lamblia
Associated Therapies
-

Study of Nitazoxanide (NTZ) Based New Therapeutic Regimens for Helicobacter Pylori

First Posted Date
2015-04-21
Last Posted Date
2017-04-25
Lead Sponsor
Sherief Abd-Elsalam
Target Recruit Count
120
Registration Number
NCT02422706
Locations
🇪🇬

Tanta university hospital, Cairo, Egypt

The Effects of Nitazoxanide in Hepatic Encephalopathy

First Posted Date
2015-01-08
Last Posted Date
2015-01-08
Lead Sponsor
Ain Shams University
Target Recruit Count
36
Registration Number
NCT02334163
Locations
🇪🇬

Faculty of medicine, Ain Shams University, Cairo, Egypt

Oral Nitazoxanide in Acute Gastroenteritis in Australian Indigenous Children

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2014-06-18
Last Posted Date
2024-02-08
Lead Sponsor
Telethon Kids Institute
Target Recruit Count
216
Registration Number
NCT02165813
Locations
🇦🇺

Alice Springs Hospital, Alice Springs, Northern Territory, Australia

🇦🇺

Royal Darwin Hospital, Darwin, Northern Territory, Australia

Nitazoxanide Versus Placebo for the Treatment of Hospitalized Subjects With Severe Acute Respiratory Illness

First Posted Date
2014-02-07
Last Posted Date
2018-08-01
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
260
Registration Number
NCT02057757
Locations
🇲🇽

Hospital Central Dr. Ignacio Morones Prieto, San Luis Potosi, Mexico

🇲🇽

Instituto Nacional de Pediatria, Coyoacan, Mexico

🇲🇽

Hospital General Dr. Aurelio Valdivieso, Oaxaca, Mexico

and more 3 locations

The Role Of Nitazoxanide, Interferon Alfa And Ribavirin In Treatment Of Hepatitis C Infected Type 2 Diabetic Patients

First Posted Date
2013-01-17
Last Posted Date
2013-09-20
Lead Sponsor
Services Institute of Medical Sciences, Pakistan
Target Recruit Count
66
Registration Number
NCT01770483
Locations
🇵🇰

Endocrinology and Diabetes management centre, Lahore, Punjab, Pakistan

Irritable Bowel Syndrome Evaluation and Treatment in Primary Care

First Posted Date
2012-07-16
Last Posted Date
2019-01-23
Lead Sponsor
American Academy of Family Physicians
Target Recruit Count
61
Registration Number
NCT01641341
Locations
🇺🇸

Baton Rouge Family Practice, Baton Rouge, Louisiana, United States

🇺🇸

American Academy of Family Physicians-National Research Network, Leawood, Kansas, United States

🇺🇸

Torrance Clinical Research, Lomita, California, United States

and more 6 locations

Safety and Efficacy Study of Nitazoxanide in the Treatment of Acute Uncomplicated Influenza

First Posted Date
2012-06-01
Last Posted Date
2018-03-29
Lead Sponsor
Romark Laboratories L.C.
Target Recruit Count
1941
Registration Number
NCT01610245
Locations
🇦🇺

Influence Study SIte, Nedlands, Western Australia, Australia

🇳🇿

Influence Study Site, Christchurch Central, Christchurch, New Zealand

Efficacy of Pegylated Interferon Plus Ribavirin Plus Nitazoxanide in HCV Genotype 4 and HIV Coinfection

First Posted Date
2012-02-08
Last Posted Date
2015-01-14
Lead Sponsor
Juan Macías
Target Recruit Count
45
Registration Number
NCT01529073
Locations
🇪🇸

H.U. Valme, Seville, Spain

Efficacy Study of Nitazoxanide Suspension in the Treatment of Rotavirus Disease in Children

First Posted Date
2011-04-05
Last Posted Date
2011-04-05
Lead Sponsor
Romark Laboratories L.C.
Target Recruit Count
100
Registration Number
NCT01328925
Locations
🇪🇬

Cairo University Children's Hospital, Cairo, Egypt

Nitazoxanide for the Treatment of Prolonged Diarrhea in Children

Phase 3
Completed
Conditions
Interventions
First Posted Date
2011-03-30
Last Posted Date
2011-03-30
Lead Sponsor
Romark Laboratories L.C.
Target Recruit Count
100
Registration Number
NCT01326338
Locations
🇵🇪

Regional Hospital of Cajamarca, Cajamarca, Peru

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