DeepMed Research

Avibactam Sodium/Ceftazidime

Generic Name: Avibactam Sodium/Ceftazidime

Clinical Trials

Study to Assess Efficacy and Safety of PF-06947386 in Japanese Adult Patients With Complicated Intra-abdominal Infection

Phase 3

Completed

Conditions: Complicated Intra-abdominal Infection

Interventions: Drug: PF-06947386
Drug: Metronidazole

First Posted Date: 2021-06-15

Last Posted Date: 2024-03-13

Lead Sponsor: Pfizer

Target Recruit Count: 60

Registration Number: NCT04927312

Locations: 🇯🇵
Saiseikai Maebashi Hospital, Maebashi, Gunma, Japan
🇯🇵
Yamagata City Hospital Saiseikan, Yamagata, Japan
🇯🇵
National Hospital Organization Osaka Minami Medical Center, Kawachinagano, Osaka, Japan

and more 25 locations

Comparative Study of Ceftazidime-Avibactam Versus Standard of Care as Therapy in Febrile Neutropenic Adults With Cancer

Phase 2

Terminated

Conditions: Neoplasms
Febrile Neutropenia

Interventions: Drug: CAZ-AVI
Drug: Vancomycin
Drug: Linezolid
Drug: Cefepime
Drug: Meropenem
Drug: Piperacillin/tazobactam

First Posted Date: 2016-04-08

Last Posted Date: 2017-07-21

Lead Sponsor: Forest Laboratories

Target Recruit Count: 2

Registration Number: NCT02732327

Locations: 🇺🇸
MD Anderson Cancer Center, Houston, Texas, United States

A Phase I Study to Assess the Safety, Tolerability and PK of Ceftazidime-Avibactam in Healthy Chinese Subjects

Phase 1

Completed

Conditions: Healthy Volunteers

Interventions: Drug: CAZ-AVI
Drug: 0.9% Normal Saline

First Posted Date: 2013-08-12

Last Posted Date: 2017-09-05

Lead Sponsor: Pfizer

Target Recruit Count: 42

Registration Number: NCT01920399

Locations: 🇨🇳
Research Site, Shanghai, China

Safety and Tolerability of Ceftazidime-Avibactam for Pediatric Patients With Suspected or Confirmed Infections

Phase 1

Completed

Conditions: Systemic Infections

Interventions: Drug: CAZ-AVI

First Posted Date: 2013-07-09

Last Posted Date: 2017-09-06

Lead Sponsor: Pfizer

Target Recruit Count: 35

Registration Number: NCT01893346

Locations: 🇺🇸
Research Site, Morgantown, West Virginia, United States

A Study to Investigate the Effect of Administration of Ceftazidime-avibactam (CAZ-AVI) and Ceftaroline Fosamil -Avibactam (CXL) on the Intestinal Flora of Healthy Volunteers

Phase 1

Completed

Conditions: Pharmacokinetics
Open Label
CXL
Effect on Intestinal Flora
CAZ-AVI
Safety

Interventions: Drug: CAZ-AVI
Drug: CXL

First Posted Date: 2013-02-12

Last Posted Date: 2017-09-05

Lead Sponsor: Pfizer

Target Recruit Count: 48

Registration Number: NCT01789528

Locations: 🇸🇪
Research Site, Stockholm, Sweden

A Study to Assess the Levels of CAZ-AVI and Metronidazole in the Blood When Given Together and Separately

Phase 1

Completed

Conditions: Healthy

Interventions: Drug: CAZ-AVI
Drug: metronidazole
Drug: CAZ-AVI + metronidazole

First Posted Date: 2012-02-16

Last Posted Date: 2017-09-05

Lead Sponsor: Pfizer

Target Recruit Count: 28

Registration Number: NCT01534247

Locations: 🇺🇸
Research site, Overland Park, Kansas, United States

Compare Ceftazidime-Avibactam + Metronidazole Versus Meropenem for Hospitalized Adults With Complicated Intra-Abdominal Infections

Phase 3

Completed

Conditions: Complicated Intra-Abdominal Infection

Interventions: Drug: Meropenem
Drug: CAZ-AVI
Drug: Metronidazole

First Posted Date: 2011-12-26

Last Posted Date: 2017-09-06

Lead Sponsor: Pfizer

Target Recruit Count: 493

Registration Number: NCT01499290

Locations: 🇺🇦
Research Site, Zaporizhzhya, Ukraine

Prev
1
Next

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2025. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy