Vitamin A

Generic Name: Vitamin A

Brand Names: Aquasol A, Infuvite, Infuvite Pediatric, Mvc-fluoride, Mvi Pediatric, Vitafol-one

Drug Type: Small Molecule

Chemical Formula: C_₂₀H_₃₀O

CAS Number: 68-26-8

Unique Ingredient Identifier: G2SH0XKK91

Background: Retinol and derivatives of retinol that play an essential role in metabolic functioning of the retina, the growth of and differentiation of epithelial tissue, the growth of bone, reproduction, and the immune response. Dietary vitamin A is derived from a variety of carotenoids found in plants. It is enriched in the liver, egg yolks, and the fat component of d...

Indication: For the treatment of vitamin A deficiency.

Associated Conditions: Deficiency, Vitamin A, Deficiency, Vitamin D, Degenerative Retinal Disorders, Disorder of the Epithelium, Disorder of the Mesoderm, Inner ear disorder, Vitamin Deficiency, Vitamin E Deficiency

Associated Therapies: Nutritional supplementation

Clinical Trials

Comparison of the Cosmetic Effects of Bakuchiol and Retinol

Early Phase 1

Completed

Conditions: Wrinkle
Photoaging

Interventions: Drug: Bakuchiol
Drug: Retinol

First Posted Date: 2017-04-13

Last Posted Date: 2021-11-02

Lead Sponsor: University of California, Davis

Target Recruit Count: 44

Registration Number: NCT03112863

Locations: 🇺🇸
UC Davis Department of Dermatology, Sacramento, California, United States

Vitamin A and Azithromycin for Acne Vulgaris

Early Phase 1

Conditions: Acne Vulgaris

Interventions: Drug: Vitamin A
Drug: Azithromycin

First Posted Date: 2017-03-24

Last Posted Date: 2021-02-25

Lead Sponsor: Manchanda Medical Clinic

Target Recruit Count: 30

Registration Number: NCT03090048

Locations: 🇨🇦
Manchanda Mc, Surrey, British Columbia, Canada

Retinol on Human Skin Aging in East Asian Descent

Phase 4

Completed

Conditions: Intrinsic Aging of Skin

Interventions: Drug: Retinol
Drug: Placebo

First Posted Date: 2016-09-20

Last Posted Date: 2019-04-16

Lead Sponsor: Stanford University

Target Recruit Count: 110

Registration Number: NCT02906566

Locations: 🇺🇸
Stanford Dermatology, Redwood City, California, United States

Study of Vitamin A and Carbomer in Comforting the Ocular Surface Irritations of Glaucoma Patients

Not Applicable

Completed

Conditions: Primary Open-angle Glaucoma

Interventions: Drug: carbomer eye gel
Drug: Vitamin A

First Posted Date: 2014-03-04

Last Posted Date: 2014-03-05

Lead Sponsor: Xiaodong Zhou

Target Recruit Count: 30

Registration Number: NCT02077231

The Effect of Vitamin A on Atherosclerosis

Phase 4

Conditions: Atherosclerosis

Interventions: Drug: Vitamin A
Drug: placebo

First Posted Date: 2011-08-11

Last Posted Date: 2011-08-11

Lead Sponsor: Tehran University of Medical Sciences

Target Recruit Count: 45

Registration Number: NCT01414972

Locations: 🇮🇷
Tehran University of Medical Sciences, School of Public Health, Tehran, Iran, Islamic Republic of

Comparison of Retinol 1.0% and Tretinoin 0.02% in the Treatment of Moderate to Severe Photodamage and Wrinkles

Phase 2

Completed

Conditions: Photodamaged Skin
Wrinkles

Interventions: Drug: Retinol
Drug: Tretinoin

First Posted Date: 2011-01-26

Last Posted Date: 2016-04-04

Lead Sponsor: Johns Hopkins University

Target Recruit Count: 24

Registration Number: NCT01283464

Locations: 🇺🇸
Johns Hopkins Dept. of Dermatology, Baltimore, Maryland, United States

Vitamin A Supplementation for Extremely-Low-Birth-Weight Infants

Phase 1

Completed

Conditions: Infant, Low Birth Weight
Infant, Premature
Respiration, Artificial
Respiratory Distress Syndrome, Newborn
Sepsis
Infant, Newborn
Infant, Small for Gestational Age
Bronchopulmonary Dysplasia

Interventions: Other: Sham Procedure
Drug: Vitamin A

First Posted Date: 2010-09-16

Last Posted Date: 2017-09-26

Lead Sponsor: NICHD Neonatal Research Network

Target Recruit Count: 807

Registration Number: NCT01203488

Locations: 🇺🇸
Emory University, Atlanta, Georgia, United States
🇺🇸
Indiana University, Indianapolis, Indiana, United States
🇺🇸
Case Western Reserve University, Rainbow Babies and Children's Hospital, Cleveland, Ohio, United States

and more 8 locations

Efficacy of Newborn Vitamin A Supplementation Versus Placebo in Improving Child Survival (NeoVitA Trial)

Not Applicable

Completed

Conditions: Neonatal Vitamin A Supplementation

Interventions: Drug: Vitamin A

First Posted Date: 2010-06-07

Last Posted Date: 2015-06-01

Lead Sponsor: Society for Applied Studies

Target Recruit Count: 44984

Registration Number: NCT01138449

Locations: 🇮🇳
Society for Applied Studies, New Delhi, Delhi, India

The Study of the Effects of Vitamin A on Immune System in Patients With Atherosclerosis

Phase 4

Conditions: Atherosclerosis

Interventions: Drug: placebo
Drug: vitamin A

First Posted Date: 2009-08-21

Last Posted Date: 2012-06-05

Lead Sponsor: Tehran University of Medical Sciences

Target Recruit Count: 60

Registration Number: NCT00963222

Locations: 🇮🇷
Tehran University of Medical Sciences, School of Public Health, Tehran, Iran, Islamic Republic of

Vitamin A Supplementation for Modulation of Mycobacterium Tuberculosis Immune Responses in Latent Tuberculosis

Not Applicable

Withdrawn

Conditions: Latent Tuberculosis Infection

Interventions: Drug: Vitamin A placebo
Drug: Vitamin A

First Posted Date: 2007-11-15

Last Posted Date: 2015-04-09

Lead Sponsor: Medical Research Council Unit, The Gambia

Registration Number: NCT00558480

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