Escitalopram
- Generic Name
- Escitalopram
- Brand Names
- Cipralex, Lexapro
- Drug Type
- Small Molecule
- Chemical Formula
- C20H21FN2O
- CAS Number
- 128196-01-0
- Unique Ingredient Identifier
- 4O4S742ANY
- Background
Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety. Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...
- Indication
Escitalopram is indicated for the acute and maintenance treatment of major depressive disorder (MDD) in adults and pediatric patients 12 years old and older and for the acute treatment of generalized anxiety disorder (GAD) in adults and pediatric patients 7 years old and older. It is additionally indicated for symptomatic relief of obsessive-compulsive disor...
- Associated Conditions
- Anxiety, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD)
- Associated Therapies
- -
Serotonergic Modulation of Motor Function in Subacute and Chronic SCI
- First Posted Date
- 2013-02-11
- Last Posted Date
- 2019-04-22
- Lead Sponsor
- Shirley Ryan AbilityLab
- Target Recruit Count
- 42
- Registration Number
- NCT01788969
- Locations
- 🇺🇸
Rehabilitation Institute of Chicago, Chicago, Illinois, United States
Algorithm Guided Treatment Strategies for Major Depressive Disorder
- Conditions
- Interventions
- First Posted Date
- 2013-01-10
- Last Posted Date
- 2013-01-10
- Lead Sponsor
- Shanghai Mental Health Center
- Target Recruit Count
- 1080
- Registration Number
- NCT01764867
- Locations
- 🇨🇳
Shanghai Mental Health Center, Shanghai, China
Monoaminergic Modulation of Motor Function in Subacute Incomplete Spinal Cord Injury (SCI)
- First Posted Date
- 2012-12-20
- Last Posted Date
- 2019-04-22
- Lead Sponsor
- Shirley Ryan AbilityLab
- Target Recruit Count
- 88
- Registration Number
- NCT01753882
- Locations
- 🇺🇸
Rehabilitation Institute of Chicago, Chicago, Illinois, United States
Efficacy and Safety Study of ABT-436 in Major Depressive Disorder
- Conditions
- Interventions
- First Posted Date
- 2012-12-04
- Last Posted Date
- 2013-10-08
- Lead Sponsor
- AbbVie (prior sponsor, Abbott)
- Target Recruit Count
- 19
- Registration Number
- NCT01741142
- Locations
- 🇺🇸
Site Reference ID/Investigator# 87225, South Miami, Florida, United States
🇺🇸Site Reference ID/Investigator# 87226, Portland, Oregon, United States
🇺🇸Site Reference ID/Investigator# 88876, Seattle, Washington, United States
Emotional and Cognitive Control in Late-Onset Depression
- Conditions
- Interventions
- First Posted Date
- 2012-11-16
- Last Posted Date
- 2020-10-06
- Lead Sponsor
- Weill Medical College of Cornell University
- Target Recruit Count
- 121
- Registration Number
- NCT01728194
- Locations
- 🇺🇸
Weill Cornell Medical College, New York, New York, United States
🇺🇸Weill Cornell Medical College - Westchester Division, White Plains, New York, United States
Canadian Biomarker Integration Network for Depression Study
- Conditions
- Interventions
- First Posted Date
- 2012-08-02
- Last Posted Date
- 2018-05-11
- Lead Sponsor
- University Health Network, Toronto
- Target Recruit Count
- 211
- Registration Number
- NCT01655706
- Locations
- 🇨🇦
University of British Columbia, Vancouver, British Columbia, Canada
🇨🇦University Health Network, Toronto, Ontario, Canada
🇨🇦University of Calgary, Calgary, Alberta, Canada
Serotonergic System and Violent Video Games
- First Posted Date
- 2012-07-18
- Last Posted Date
- 2015-09-29
- Lead Sponsor
- RWTH Aachen University
- Target Recruit Count
- 47
- Registration Number
- NCT01644071
- Locations
- 🇩🇪
Department of Psychiatry, Psychotherapy and Psychosomatics, University Hospital Aachen, Aachen, Germany
A PET Study to Determine Alterations in Serotonin Levels in Human Brain After a Single Dose of Escitalopram
- Conditions
- First Posted Date
- 2012-07-12
- Last Posted Date
- 2012-07-12
- Lead Sponsor
- Karolinska Institutet
- Target Recruit Count
- 10
- Registration Number
- NCT01638689
- Locations
- 🇸🇪
PET center, Department of Clinical neuroscience, Karolinska Institutet, Stockholm, Sweden
Modafinil - Escitalopram Study for Cocaine Dependence
- Conditions
- Interventions
- First Posted Date
- 2012-05-18
- Last Posted Date
- 2012-05-18
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 68
- Registration Number
- NCT01601730
- Locations
- 🇺🇸
Michael E. DeBakey VA Medical Center, Houston, Texas, United States
Lexapro®'s Efficacy After Dose Escalation in Remission Study
- First Posted Date
- 2012-05-09
- Last Posted Date
- 2018-09-07
- Lead Sponsor
- Seoul National University Hospital
- Target Recruit Count
- 60
- Registration Number
- NCT01594866
- Locations
- 🇰🇷
Seoul National University Hospital, Seoul, Korea, Republic of
Drug Development Updates
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