Escitalopram

Generic Name
Escitalopram
Brand Names
Cipralex, Lexapro
Drug Type
Small Molecule
Chemical Formula
C20H21FN2O
CAS Number
128196-01-0
Unique Ingredient Identifier
4O4S742ANY
Background

Escitalopram is a selective serotonin re-uptake inhibitor (SSRI) and the S-enantiomer of racemic citalopram. It is used to restore serotonergic function in the treatment of depression and anxiety. Escitalopram is approximately 150 times more potent than citalopram’s R-enantiomer and is responsible for the vast majority of citalopram’s clinical activity, with...

Indication

Escitalopram is indicated for the acute and maintenance treatment of major depressive disorder (MDD) in adults and pediatric patients 12 years old and older and for the acute treatment of generalized anxiety disorder (GAD) in adults and pediatric patients 7 years old and older. It is additionally indicated for symptomatic relief of obsessive-compulsive disor...

Associated Conditions
Anxiety, Generalized Anxiety Disorder, Major Depressive Disorder (MDD), Obsessive Compulsive Disorder (OCD)
Associated Therapies
-

Depression-Diabetes Mechanisms: Urban African Americans

First Posted Date
2005-09-21
Last Posted Date
2015-07-29
Lead Sponsor
Emory University
Target Recruit Count
20
Registration Number
NCT00209170
Locations
🇺🇸

Grady Hospital Diabetes Clinic, Atlanta, Georgia, United States

The Effects of Increased Central Serotonergic Activity on Information Processing

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2005-09-21
Last Posted Date
2011-09-19
Lead Sponsor
University of Copenhagen
Target Recruit Count
40
Registration Number
NCT00206934
Locations
🇩🇰

Center for Neuropsychiatric Schizophrenia Research, University of Copenhagen, Psychiatric Center Glostrup, Glostrup, Denmark

Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder

First Posted Date
2005-09-21
Last Posted Date
2010-05-27
Lead Sponsor
Hospital Universitari Vall d'Hebron Research Institute
Target Recruit Count
42
Registration Number
NCT00209807
Locations
🇪🇸

Hospital Universitari vall d'Hebron, Barcelona, Catalonia, Spain

Treatment Choices for Improving Adherence and Outcome

Not Applicable
Completed
Conditions
First Posted Date
2005-09-19
Last Posted Date
2013-11-03
Lead Sponsor
Weill Medical College of Cornell University
Target Recruit Count
60
Registration Number
NCT00194948
Locations
🇺🇸

Weill Medical College of Cornell University, White Plains, New York, United States

🇺🇸

Cornell Internal Medicine Associates, New York, New York, United States

Serotonin Transporter Inhibitor Escitalopram in Pulmonary Hypertension

Phase 3
Completed
Conditions
Interventions
First Posted Date
2005-09-19
Last Posted Date
2011-02-18
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
30
Registration Number
NCT00190333
Locations
🇫🇷

Louis Pradel Hospital, Bron, France

🇫🇷

Henri Mondor Hospital, Creteil, France

🇫🇷

Haut Lévèque Hospital, Pessac, France

and more 6 locations

Brain Energy Metabolism in Individuals With Major Depressive Disorder Receiving Escitalopram

Phase 4
Completed
Conditions
Interventions
First Posted Date
2005-09-16
Last Posted Date
2017-01-04
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
97
Registration Number
NCT00183677
Locations
🇺🇸

Massachusetts General Hospital, Boston, Massachusetts, United States

Antidepressant Medication Plus Donepezil for Treating Late-life Depression

First Posted Date
2005-09-15
Last Posted Date
2013-02-06
Lead Sponsor
University of Pittsburgh
Target Recruit Count
220
Registration Number
NCT00177671
Locations
🇺🇸

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

Augmenting Antidepressant Treatment With Interpersonal Psychotherapy for Treating Late-life Depression

First Posted Date
2005-09-15
Last Posted Date
2012-01-12
Lead Sponsor
University of Pittsburgh
Target Recruit Count
319
Registration Number
NCT00177294
Locations
🇺🇸

University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

Characteristics of Sleep Patterns in Young Adults With and Without Insomnia

First Posted Date
2005-09-15
Last Posted Date
2016-03-30
Lead Sponsor
University of Pittsburgh
Target Recruit Count
69
Registration Number
NCT00177216
Locations
🇺🇸

Western Psychiatric Institute and Clinic/ University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States

Efficacy and Safety of Escitalopram for Prevention of Depression Induced by Peg-Interferon in Hepatitis C Patients

First Posted Date
2005-09-14
Last Posted Date
2020-08-17
Lead Sponsor
Germans Trias i Pujol Hospital
Target Recruit Count
133
Registration Number
NCT00166296
Locations
🇪🇸

Fundacion Hospital Alcorcon, Alcorcon, Spain

🇪🇸

Hospital Puerta de Hierro, Madrid, Spain

🇪🇸

Hospital Nuestra Señora de Sonsoles, Avila, Spain

and more 12 locations
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