Ketamine
- Generic Name
- Ketamine
- Brand Names
- Ketalar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16ClNO
- CAS Number
- 6740-88-1
- Unique Ingredient Identifier
- 690G0D6V8H
- Background
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
- Indication
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Ketamine as a Supplement to Local Anesthesia for Minor Procedures
- Conditions
- Interventions
- First Posted Date
- 2024-02-29
- Last Posted Date
- 2024-03-15
- Lead Sponsor
- Loyola University
- Target Recruit Count
- 108
- Registration Number
- NCT06284473
- Locations
- 🇺🇸
Loyola University Medical Center, Maywood, Illinois, United States
Ketamine Versus Propofol as ICU Sedation
- Conditions
- Interventions
- First Posted Date
- 2024-02-06
- Last Posted Date
- 2024-02-06
- Lead Sponsor
- Menoufia University
- Target Recruit Count
- 100
- Registration Number
- NCT06243822
- Locations
- 🇪🇬
Menoufia University, Shibīn Al Kawm, Menoufia, Egypt
Ketamine for Veterans With Parkinson's Disease
- First Posted Date
- 2024-01-30
- Last Posted Date
- 2024-08-12
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 80
- Registration Number
- NCT06231563
- Locations
- 🇺🇸
San Francisco VA Medical Center, San Francisco, CA, San Francisco, California, United States
Neural Circuit Effects of Ketamine in Depression
- First Posted Date
- 2024-01-19
- Last Posted Date
- 2024-02-15
- Lead Sponsor
- Icahn School of Medicine at Mount Sinai
- Target Recruit Count
- 120
- Registration Number
- NCT06213324
- Locations
- 🇺🇸
Icahn School of Medicine at Mount Sinai, New York, New York, United States
Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2023-12-29
- Last Posted Date
- 2023-12-29
- Lead Sponsor
- University of Patras
- Target Recruit Count
- 50
- Registration Number
- NCT06185127
- Locations
- 🇬🇷
Naval Hospital, Athens, Attica, Greece
Use of Ketamine for Conscious Sedation in Flexible Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2023-12-26
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- Brooke Army Medical Center
- Target Recruit Count
- 66
- Registration Number
- NCT06181188
- Locations
- 🇺🇸
Brooke Army Medical Center, San Antonio, Texas, United States
Effect of Ketamine and Etomidate During RSI on Long Term Outcomes
- Conditions
- Interventions
- First Posted Date
- 2023-12-22
- Last Posted Date
- 2023-12-22
- Lead Sponsor
- Vanderbilt University Medical Center
- Target Recruit Count
- 1756
- Registration Number
- NCT06179485
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
Effect of Ketamine on Intraoperative Motor Evoked Potentials
- First Posted Date
- 2023-11-21
- Last Posted Date
- 2024-02-12
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 20
- Registration Number
- NCT06140927
- Locations
- 🇺🇸
University of California, San Francisco, San Francisco, California, United States
Intranasal Ketamine Effectiveness in Reducing Intramuscular Injection Pain Before Sedation Among Children
- First Posted Date
- 2023-11-18
- Last Posted Date
- 2024-06-04
- Lead Sponsor
- Tehran University of Medical Sciences
- Target Recruit Count
- 84
- Registration Number
- NCT06139380
- Locations
- 🇮🇷
IKHC, Tehran, Iran, Islamic Republic of
Ketamine and Neurofeedback-Training: Effects on Neuroplasticity in Cocaine Addiction
- First Posted Date
- 2023-11-09
- Last Posted Date
- 2024-12-20
- Lead Sponsor
- Dr. med. Marcus Herdener
- Target Recruit Count
- 120
- Registration Number
- NCT06125054
- Locations
- 🇨🇭
Psychiatric University Hospital Zurich, University of Zurich, Zürich, Switzerland
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.