Ketamine
- Generic Name
- Ketamine
- Brand Names
- Ketalar
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16ClNO
- CAS Number
- 6740-88-1
- Unique Ingredient Identifier
- 690G0D6V8H
- Background
Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...
- Indication
Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Ketamine Sedation in Mechanically Ventilated Patients
- Conditions
- First Posted Date
- 2005-07-22
- Last Posted Date
- 2007-07-23
- Lead Sponsor
- Assistance Publique - Hôpitaux de Paris
- Target Recruit Count
- 100
- Registration Number
- NCT00122759
- Locations
- 🇫🇷
Service de Réanimation Médicale, Hôpital Louis Mourier, Colombes, France
Rapid Antidepressant Effects of Ketamine in Major Depression
- Conditions
- Interventions
- First Posted Date
- 2004-08-02
- Last Posted Date
- 2018-10-12
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Target Recruit Count
- 67
- Registration Number
- NCT00088699
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Drug Development Updates
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