Ketamine

Generic Name
Ketamine
Brand Names
Ketalar
Drug Type
Small Molecule
Chemical Formula
C13H16ClNO
CAS Number
6740-88-1
Unique Ingredient Identifier
690G0D6V8H
Background

Ketamine is an NMDA receptor antagonist with a potent anesthetic effect. It was developed in 1963 as a replacement for phencyclidine (PCP) by Calvin Stevens at Parke Davis Laboratories. It started being used for veterinary purposes in Belgium and in 1964 was proven that compared to PCP, it produced minor hallucinogenic effects and shorter psychotomimetic eff...

Indication

Ketamine is indicated as an anesthetic agent for recommended diagnostic and surgical procedures. If skeletal muscle relaxation is needed, it should be combined with a muscle relaxant. If the surgical procedure involves visceral pain, it should be supplemented with an agent that obtunds visceral pain. Ketamine can be used for induction of anesthesia prior oth...

Associated Conditions
-
Associated Therapies
General Anesthesia, Induction and Maintenance of General Anesthesia

Magnesium and Cramping

First Posted Date
2024-12-20
Last Posted Date
2024-12-20
Lead Sponsor
William Beaumont Hospitals
Target Recruit Count
150
Registration Number
NCT06745388
Locations
🇺🇸

Corewell Health William Beaumont University Hospital, Royal Oak, Michigan, United States

Pro-Epileptic Effects of IV Ketamine

Phase 4
Active, not recruiting
Conditions
Interventions
First Posted Date
2024-12-19
Last Posted Date
2024-12-20
Lead Sponsor
Haseki Training and Research Hospital
Target Recruit Count
300
Registration Number
NCT06741930
Locations
🇹🇷

Haseki Training and Research Hospital, Istanbul, Turkey

Intravenous Ketamine for Treatment-Resistant Depression

First Posted Date
2024-10-31
Last Posted Date
2024-11-21
Lead Sponsor
Mayo Clinic
Target Recruit Count
30
Registration Number
NCT06668571
Locations
🇺🇸

Mayo Clinic in Rochester, Rochester, Minnesota, United States

Comparing Ketamine and Fentanyl in Pediatric Tonsillectomy: Pain Control and Emergence Delirium Outcomes (KVFPT)

First Posted Date
2024-10-08
Last Posted Date
2024-10-30
Lead Sponsor
Medipol University
Target Recruit Count
59
Registration Number
NCT06630364
Locations
🇹🇷

Medipol Mega University Hospital, Istanbul, Bagcılar, Turkey

FMRI of Patients Receiving IV Ketamine for Treatment Resistant Bipolar Depression

First Posted Date
2024-10-01
Last Posted Date
2024-12-13
Lead Sponsor
Brian Barnett
Target Recruit Count
20
Registration Number
NCT06620042
Locations
🇺🇸

Cleveland Clinic Lutheran Hospital, Ohio City, Ohio, United States

The Impact of Preoperative Suggestion on Dreaming

First Posted Date
2024-09-24
Last Posted Date
2024-09-24
Lead Sponsor
Wonkwang University Hospital
Target Recruit Count
250
Registration Number
NCT06609538
Locations
🇰🇷

WonwangUH, Iksan, Please Select, Korea, Republic of

Pain Palliation in Forearm Fractures in the Emergency Department

First Posted Date
2024-09-19
Last Posted Date
2024-10-01
Lead Sponsor
Ankara Etlik City Hospital
Target Recruit Count
78
Registration Number
NCT06588907
Locations
🇹🇷

Ankara Etlik City Hospital, Ankara, Yenimahalle, Turkey

Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of Depression

First Posted Date
2024-08-19
Last Posted Date
2024-08-19
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
70
Registration Number
NCT06559826
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

Ketofol Versus Dexmedetomidine for Prevention of Emergence Delirium in Pediatric Patients Undergoing Squint Surgeries

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2024-08-09
Last Posted Date
2024-08-20
Lead Sponsor
Cairo University
Target Recruit Count
46
Registration Number
NCT06545890
Locations
🇪🇬

Abu Elresh Hospitals ( Cairo university ), Cairo, Egypt

🇪🇬

Abu ElResh hospital, Cairo, Egypt

Ketamine Therapy for Methamphetamine Use Disorder & HIV

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-08-05
Last Posted Date
2024-08-06
Lead Sponsor
Nicky Mehtani, MD, MPH
Target Recruit Count
12
Registration Number
NCT06538285
Locations
🇺🇸

San Francisco Department of Public Health, San Francisco, California, United States

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