Codeine
- Generic Name
- Codeine
- Brand Names
- Ascomp, Cheratussin, Cheratussin Dac, Codar Ar, Codar D, Codar Gf, Codeine Contin, Covan, Damylin With Codeine, Fioricet With Codeine, Histex Ac, Linctus Codeine Blanc, M-clear Wc, M-end PE, Mar-cof BP, Mar-cof Cg, Mersyndol, Ninjacof Xg, Pseudodine C, Robaxacet-8, Robaxisal, Triacin-C, Trianal C, Triatec, Triatec-30, Triatec-8, Tusnel C, Tuxarin, Tuzistra, Tylenol With Codeine
- Drug Type
- Small Molecule
- Chemical Formula
- C18H21NO3
- CAS Number
- 76-57-3
- Unique Ingredient Identifier
- UX6OWY2V7J
- Background
The relief of pain (analgesia) is a primary goal for enhancing the quality of life of patients and for increasing the ability of patients to engage in day to day activities. Codeine, an opioid analgesic, was originally approved in the US in 1950 and is a drug used to decrease pain by increasing the threshold for pain without impairing consciousness or alteri...
- Indication
Codeine sulfate is a form of this drug that is commonly used. It is available in tablet form and indicated for the relief of mild to moderately severe pain, where the use of an opioid analgesic is appropriate .
The solution form is used by itself or combined in a syrup with other drugs and is used as a cough suppressant in adults aged 18 and above , .
- Associated Conditions
- Common Cold, Cough, Flu caused by Influenza, Mild pain, Pain, Severe Pain, Dry cough, Moderate Pain, Upper respiratory symptoms
- Associated Therapies
- Airway secretion clearance therapy
Colonic Motor Patterns in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2023-03-16
- Last Posted Date
- 2023-03-16
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 15
- Registration Number
- NCT05770960
- Locations
- 🇧🇪
UZ Leuven, Leuven, Vlaams-Brabant, Belgium
COMPARISON OF EFFICACY OF DIFFERENT DRUG COMBINATIONS IN ACUTE SCIATICA
- Conditions
- Interventions
- First Posted Date
- 2022-11-23
- Last Posted Date
- 2022-11-23
- Lead Sponsor
- Pakistan Institute of Medical Sciences
- Target Recruit Count
- 120
- Registration Number
- NCT05626140
- Locations
- 🇵🇰
Mehreen Mirza, Rawalpindi, Punjab, Pakistan
Fixed Combination of Dipirone and Codeine Compared to the Isolated Use of Dipyrone and Codeine in Controlling Pain After Pelvic-abdominal Surgery.
- Conditions
- Interventions
- First Posted Date
- 2020-11-23
- Last Posted Date
- 2024-06-27
- Lead Sponsor
- Brazilian Clinical Research Institute
- Target Recruit Count
- 491
- Registration Number
- NCT04641338
- Locations
- 🇧🇷
Santa Casa de Misericórdia de Votuporanga, Votuporanga, São Paulo, Brazil
🇧🇷Hospital Universitário São Francisco na Providência de Deus, Bragança Paulista, São Paulo, Brazil
🇧🇷Associação Hospital de Caridade Ijuí - Núcleo de Ensino e Pesquisa, Ijuí, Rio Grande Do Sul, Brazil
Codeine on Pharyngeal and Esophageal Motility
- Conditions
- Interventions
- First Posted Date
- 2018-12-21
- Last Posted Date
- 2018-12-24
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 22
- Registration Number
- NCT03784105
- Locations
- 🇧🇪
Jan Tack, Leuven, Belgium
🇧🇪UZ Leuven, Leuven, Belgium
Opioid Analgesics for Acute Fracture Pain in Adults Discharged From the ED
- Conditions
- Interventions
- First Posted Date
- 2018-03-27
- Last Posted Date
- 2019-10-02
- Lead Sponsor
- Mount Sinai Hospital, Canada
- Target Recruit Count
- 5
- Registration Number
- NCT03478423
- Locations
- 🇨🇦
Mount Sinai Hospital, Toronto, Ontario, Canada
Clinical Evaluation of the VIPUN Balloon Catheter 0.1
- Conditions
- Interventions
- First Posted Date
- 2017-08-04
- Last Posted Date
- 2018-05-04
- Lead Sponsor
- Universitaire Ziekenhuizen KU Leuven
- Target Recruit Count
- 22
- Registration Number
- NCT03239821
- Locations
- 🇧🇪
UZ Leuven Gasthuisberg, Leuven, Belgium
Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects
- Conditions
- Interventions
- First Posted Date
- 2016-04-13
- Last Posted Date
- 2017-08-30
- Lead Sponsor
- Michael Camilleri
- Target Recruit Count
- 72
- Registration Number
- NCT02737059
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Codeine Plus Paracetamol Versus Placebo for PRK Post-operative Pain
- First Posted Date
- 2015-12-09
- Last Posted Date
- 2015-12-11
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 40
- Registration Number
- NCT02625753
- Locations
- 🇧🇷
Universidade de São Paulo (USP) - Refractive surgery department, São Paulo, Brazil
A Cost Effective Treatment for Headache in Pregnancy When Acetaminophen Alone is Ineffective.
- Conditions
- Interventions
- First Posted Date
- 2014-11-20
- Last Posted Date
- 2018-04-02
- Lead Sponsor
- St. Louis University
- Target Recruit Count
- 70
- Registration Number
- NCT02295280
- Locations
- 🇺🇸
Saint Louis University, Saint Louis, Missouri, United States
Repeated Dose Study for the Investigation of Heritability of and Genetic Influences on Drug Pharmacokinetics
- Conditions
- Interventions
- First Posted Date
- 2013-05-03
- Last Posted Date
- 2014-04-21
- Target Recruit Count
- 117
- Registration Number
- NCT01845194
- Locations
- 🇩🇪
Dept. of Clinical Pharmacology, Georg-August-University of Goettingen, Goettingen, Germany
Drug Development Updates
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