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Gemifloxacin

Generic Name
Gemifloxacin
Brand Names
Factive
Drug Type
Small Molecule
Chemical Formula
C18H20FN5O4
CAS Number
175463-14-6
Unique Ingredient Identifier
OKR68Y0E4T

Overview

Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.

Background

Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essential for bacterial growth.

Indication

For the treatment of bacterial infection caused by susceptible strains such as S. pneumoniae, H. influenzae, H. parainfluenzae, or M. catarrhalis, S. pneumoniae (including multi-drug resistant strains [MDRSP]), M. pneumoniae, C. pneumoniae, or K. pneumoniae.

Associated Conditions

  • Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB)
  • Bacterial Infections
  • Community Acquired Pneumonia (CAP)
  • Multidrug resistant Streptococcus pneumoniae infection
  • Neisseria Gonorrhoeae Infection
  • Bacterial rhinosinusitis

FDA Approved Products

FACTIVE
Manufacturer:Merus Labs International Inc.
Route:ORAL
Strength:320 mg in 1 1
Approved: 2016/08/03
NDC:44001-321
FACTIVE
Manufacturer:Vansen Pharma Inc.
Route:ORAL
Strength:320 mg in 1 1
Approved: 2013/09/19
NDC:44004-321

Singapore Approved Products

No Singapore products found for this drug

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