吉米沙星 (Factive)

Gemifloxacin

未知生产厂商

Gemifloxacin is a quinolone antibacterial agent used for the treatment of acute bacterial exacerbation of chronic bronchitis and mild to moderate community-acquired pneumonia caused by susceptible bacteria.

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概览

作用机制

The bactericidal action of gemifloxacin results from inhibition of the enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination.

适应症

For the treatment of bacterial infection caused by susceptible strains such as S. pneumoniae, H. influenzae, H. parainfluenzae, or M. catarrhalis, S. pneumoniae (including multi-drug resistant strains [MDRSP]), M. pneumoniae, C. pneumoniae, or K. pneumoniae.

专利

每项发明一条，涵盖美国、欧洲、PCT 与中国的同族专利。

Gemifloxacin hydrates
EP 2161270 A1申请人: HETERO DRUGS LTD优先权: 2005
EP
US
7 件公开
Methods of use fluoroquinolone compounds against maxillary sinus pathogenic bacteria
US 2005288300 A1申请人: LG LIFE SCIENCES LTD优先权: 2001
US
5 件公开
Methods of use of quinolone compounds against pneumococcal and Haemophilus bacteria
US 7595328 B2申请人: LG LIFE SCIENCES LTD优先权: 2000
US
3 件公开
Methods of use of gemifloxacin compounds against fluoroquinolone resistant streptococcus pneumoniae bacteria
- US 2002082275 A1
  申请人: BAST DARRIN优先权: 2001
  US
  3 件公开
- US 2002086868 A1
  申请人: BAST DARREN优先权: 2001
  US
- US 2003073695 A1
  申请人: BAST DARRIN优先权: 2002
  US
Methods of use of antimicrobial compounds against pathogenic mycoplasma bacteria
US 2001025048 A1申请人: SMITHKLINE BEECHAM CORP优先权: 2001
US
2 件公开
Processes for the production of amino-protected derivatives of 4-aminomethylene-pyrrolidin-3-one and/or 4-aminomethylene-pyrrolidin-3-alkoxyimino derivatives and/or gemifloxacin or a salt thereof
US 7199242 B2申请人: LG LIFE SCIENCES LTD优先权: 2001
US
2 件公开
Methods of use of quinolone compounds against anaerobic pathogenic bacteria
US 2002061893 A1申请人: SMITHKLINE BEECHAM CORP优先权: 2001
US
2 件公开
Process for preparing beta-ketoester compound
US 6987199 B2申请人: LG LIFE SCIENCES LTD优先权: 2001
US
2 件公开
Methods of use of quinolone compounds against atypical upper respiratory pathogenic bacteria
US 2002086867 A1申请人: SMITHKLINE BEECHAM CORP优先权: 2001
US
2 件公开
Process for preparing acid salts of Gemifloxacin
US 7361762 B2申请人: LG LIFE SCIENCES LTD优先权: 2002
US
2 件公开

药物

吉米沙星 (Factive)

概览

作用机制

适应症

相关疾病

专利

Methods of use of gemifloxacin compounds against fluoroquinolone resistant streptococcus pneumoniae bacteria