Gemifloxacin
- Generic Name
- Gemifloxacin
- Brand Names
- Factive
- Drug Type
- Small Molecule
- Chemical Formula
- C18H20FN5O4
- CAS Number
- 175463-14-6
- Unique Ingredient Identifier
- OKR68Y0E4T
- Background
Gemifloxacin is a quinolone antibacterial agent with a broad-spectrum activity that is used in the treatment of acute bacterial exacerbation of chronic bronchitis and mild-to-moderate pneumonia. It is available in oral formulations. Gemifloxacin acts by inhibiting DNA synthesis through the inhibition of both DNA gyrase and topoisomerase IV, which are essenti...
- Indication
For the treatment of bacterial infection caused by susceptible strains such as S. pneumoniae, H. influenzae, H. parainfluenzae, or M. catarrhalis, S. pneumoniae (including multi-drug resistant strains [MDRSP]), M. pneumoniae, C. pneumoniae, or K. pneumoniae.
- Associated Conditions
- Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Bacterial Infections, Community Acquired Pneumonia (CAP), Multidrug resistant Streptococcus pneumoniae infection, Neisseria Gonorrhoeae Infection, Bacterial rhinosinusitis
- Associated Therapies
- -
Oral Gemifloxacin Versus Intravenous Cefotaxime in Treatment of Spontaneous Bacterial Peritonitis
- Conditions
- Interventions
- First Posted Date
- 2019-11-19
- Last Posted Date
- 2019-11-19
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 60
- Registration Number
- NCT04168099
- Locations
- 🇪🇬
Sherief Abd-Elsalam, Tanta, Egypt
Comparison Between Rifampicin and Gemifloxacin and Ciprofloxacin in Treatment of Rhinoscleroma
- Conditions
- Interventions
- First Posted Date
- 2017-10-30
- Last Posted Date
- 2018-02-13
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 60
- Registration Number
- NCT03326050
- Locations
- 🇪🇬
Asmaa Ahmed, Assiut, Egypt
Efficacy of Combination Therapies for Gonorrhea Treatment
- Conditions
- Interventions
- First Posted Date
- 2009-06-24
- Last Posted Date
- 2015-08-19
- Target Recruit Count
- 614
- Registration Number
- NCT00926796
- Locations
- 🇺🇸
San Francisco Department of Public Health - San Francisco City Clinic, San Francisco, California, United States
🇺🇸University of Alabama Hospital - Infectious Diseases, Birmingham, Alabama, United States
🇺🇸Los Angeles County Department of Public Health - Sexually Transmitted Disease Program, Los Angeles, California, United States
Drug Development Updates
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