Vasopressin

Generic Name: Vasopressin

Brand Names: Vasostrict

Drug Type: Small Molecule

Chemical Formula: C_₉₂H_₁₃₀N_₂₈O_₂₄S_₄

CAS Number: 11000-17-2

Unique Ingredient Identifier: Y87Y826H08

Background: Vasopressin (arginine-vasopressin or antidiuretic hormone) is a nonapeptide primarily produced in the hypothalamus that exhibits diverse physiological functions related to diuresis, hemodynamic modulation, and behaviour. Vasopressin is very similar to oxytocin, differing in the third and eighth amino acids. Despite a wide variety of functions, exogenous vaso...

Indication: 1.诊断和治疗由于缺乏抗利尿激素而引起的尿崩症，也用于其他药物效果不佳的腹部肌肉松弛；

2.脑外科手术后或头颅创伤后多尿的初期治疗；

3.用于食管、胃肠道消化道疾病的急性大出血的辅助治疗。

Associated Conditions: Acute Circulatory Failure

Associated Therapies: Dental Local Anesthesia

Clinical Trials

Vasopressin Administration During Laparoscopic Myomectomy: a Randomized Controlled Trial

Phase 4

Completed

Conditions: Blood Loss, Surgical

Interventions: Drug: Vasopressin

First Posted Date: 2011-07-13

Last Posted Date: 2018-02-15

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 152

Registration Number: NCT01393704

Locations: 🇺🇸
Brigham&Women's hospital, Boston, Massachusetts, United States

Brain Imaging Study of Adults With Autism Spectrum Disorders

Phase 1

Completed

Conditions: Autism Spectrum Disorders

First Posted Date: 2010-03-26

Last Posted Date: 2019-12-17

Lead Sponsor: National Institute of Mental Health (NIMH)

Target Recruit Count: 38

Registration Number: NCT01093768

Locations: 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States

Study to Evaluate if the Drug Vasopressin Protects the Kidneys for Patients Undergoing Liver Transplant

Not Applicable

Completed

Conditions: Liver Failure

Interventions: Drug: Vasopressin
Drug: Normal saline placebo

First Posted Date: 2009-04-22

Last Posted Date: 2018-10-17

Lead Sponsor: Medical University of South Carolina

Target Recruit Count: 18

Registration Number: NCT00886262

Locations: 🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States

Comparison of the Effects of Cervical Vasopressin Versus no Premedication on Blood Loss During Vaginal Hysterectomy: A Randomized, Placebo Controlled Trial

Phase 4

Completed

Conditions: Blood Loss During Vaginal Hysterectomy

Interventions: Drug: Vasopressin

First Posted Date: 2008-11-27

Last Posted Date: 2018-07-24

Lead Sponsor: Ascher-Walsh, Charles, M.D.

Target Recruit Count: 58

Registration Number: NCT00799292

Locations: 🇺🇸
Columbia University Medical Center, New York, New York, United States

Trial of Vasopressin and Epinephrine to Epinephrine Only for In-Hospital Pediatric Cardiopulmonary Resuscitation

Phase 1

Completed

Conditions: Cardiac Arrest
Cardiopulmonary Arrest

Interventions: Drug: Vasopressin
Drug: Epinephrine

First Posted Date: 2008-03-05

Last Posted Date: 2019-09-17

Lead Sponsor: University of Texas Southwestern Medical Center

Target Recruit Count: 130

Registration Number: NCT00628550

Locations: 🇺🇸
Universtity of Texas Southwestern, Children's Medical Center, Dallas, Texas, United States

Continuous Infusion of Terlipressin in Septic Shock

Phase 2

Completed

Conditions: Septic Shock

Interventions: Drug: Vasopressin
Drug: Terlipressin
Drug: Norepinephrine

First Posted Date: 2007-06-01

Last Posted Date: 2008-02-29

Lead Sponsor: University of Roma La Sapienza

Target Recruit Count: 45

Registration Number: NCT00481572

Locations: 🇮🇹
Department of Anesthesiology and Intensive care of the University of Rome "La Sapienza", Rome, Viale del Policlinico 155, Italy

Low Dose Vasopressin in Traumatic Shock

Early Phase 1

Terminated

Conditions: Injuries
Shock, Traumatic

Interventions: Drug: normal saline control
Drug: vasopressin

First Posted Date: 2007-01-11

Last Posted Date: 2019-06-18

Lead Sponsor: The University of Texas Health Science Center at San Antonio

Target Recruit Count: 81

Registration Number: NCT00420407

Locations: 🇺🇸
University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States

Vasopressin in Traumatic Hemorrhagic Shock Study

Phase 2

Completed

Conditions: Shock
Hypovolemia
Hemorrhagic Shock

Interventions: Drug: Vasopressin
Drug: Saline placebo

First Posted Date: 2006-09-22

Last Posted Date: 2014-11-05

Lead Sponsor: Volker Wenzel

Target Recruit Count: 64

Registration Number: NCT00379522

Locations: 🇦🇹
Medical University of Innsbruck, Innsbruck, Tyrol, Austria
🇩🇪
University Hospital of Mannheim, Mannheim, Germany
🇩🇪
University Hospital of Goettingen, Goettingen, Germany

and more 11 locations

Comparing Vasopressin and Adrenaline in Patients With Cardiac Arrest

Phase 3

Completed

Conditions: Cardiac Arrest

Interventions: Drug: Adrenaline
Drug: Vasopressin

First Posted Date: 2006-08-01

Last Posted Date: 2017-03-17

Lead Sponsor: Singapore General Hospital

Target Recruit Count: 727

Registration Number: NCT00358579

Locations: 🇸🇬
Changi General Hospital, Singapore, Singapore
🇸🇬
Singapore General Hospital, Singapore, Singapore
🇸🇬
National University Hospital, Singapore, Singapore

and more 1 locations

Comparison of Vasopressin and Other Pressors in Septic Shock

Phase 2

Completed

Conditions: Shock, Septic

First Posted Date: 2005-12-23

Last Posted Date: 2006-05-29

Lead Sponsor: Université de Sherbrooke

Target Recruit Count: 20

Registration Number: NCT00269685

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

Home Terms & Conditions Privacy Policy