MedPath

Acitretin

Generic Name
Acitretin
Brand Names
Soriatane
Drug Type
Small Molecule
Chemical Formula
C21H26O3
CAS Number
55079-83-9
Unique Ingredient Identifier
LCH760E9T7
Background

An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.

Indication

For the treatment of severe psoriasis in adults.

Associated Conditions
Keratinization disorders, Severe Psoriasis
Clinical Trials
Related News

Systemic Treatment Options for Generalized Lichen Planus

Phase 2
Not yet recruiting
Conditions
Lichen Planus
Interventions
First Posted Date
2024-12-18
Last Posted Date
2024-12-18
Lead Sponsor
Sheikh Zayed Medical College
Target Recruit Count
124
Registration Number
NCT06739551
Locations
🇵🇰

Sheikh zayed Medical College and Hospital, Rahim Yar Khan, Punjab, Pakistan

Effect of Acitretin Versus Narrowband Ultraviolet B on Neopterin Level in Psoriatic Patients .

Phase 4
Conditions
Psoriasis
Interventions
Radiation: Narrowband ultraviolet B
First Posted Date
2022-06-02
Last Posted Date
2022-06-02
Lead Sponsor
South Valley University
Target Recruit Count
30
Registration Number
NCT05401006
Locations
🇪🇬

South Valley University, Qinā, Egypt

Omentin-1 Level in Psoriatic Patients Treated With Narrowband Ultraviolet B Phototherapy Versus Acitretin

Phase 4
Completed
Conditions
Psoriasis
Interventions
Radiation: Narrowband Ultraviolet B
First Posted Date
2022-01-24
Last Posted Date
2022-01-24
Lead Sponsor
Mahmoud Ahmed Ali Ahmed
Target Recruit Count
60
Registration Number
NCT05203354
Locations
🇪🇬

Faculty of medicine - Aswan university, Aswan, Egypt

Plexin B2 Gene Expression and Polymorphisms in Psoriasis

Phase 1
Completed
Conditions
Psoriasis Vulgaris
Interventions
Radiation: Narrow band Ultraviolet B phototherapy group
Combination Product: Acitretin plus Narrow band Ultraviolet B phototherapy group
First Posted Date
2022-01-11
Last Posted Date
2023-09-21
Lead Sponsor
South Valley University
Target Recruit Count
200
Registration Number
NCT05184348
Locations
🇪🇬

Faculty of Medicine , South Valley University, Qina, Egypt

Outcomes With Treatment and Withdraw of Ixekizumab in Patients With Plaque Psoriasis

Phase 4
Recruiting
Conditions
Plaque Psoriasis
Interventions
Biological: Ixekizumab
First Posted Date
2020-09-03
Last Posted Date
2022-11-25
Lead Sponsor
Singapore General Hospital
Target Recruit Count
40
Registration Number
NCT04537689
Locations
🇸🇬

Singapore General Hospital, Outram Park, Singapore

Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation

Not Applicable
Conditions
Xerosis
Hyperlipidemias
Liver Diseases
Depression
Interventions
Other: Narrow band ultraviolet B
First Posted Date
2020-01-28
Last Posted Date
2021-07-22
Lead Sponsor
Cairo University
Target Recruit Count
20
Registration Number
NCT04245319
Locations
🇪🇬

Cairo University, Cairo, Egypt

Outcomes With Treatment and Withdraw of Secukinumab in Patients With Plaque Psoriasis

Phase 4
Not yet recruiting
Conditions
Plaque Psoriasis
Interventions
Biological: secukinumab
First Posted Date
2020-01-27
Last Posted Date
2022-11-25
Lead Sponsor
Singapore General Hospital
Target Recruit Count
40
Registration Number
NCT04239859
Locations
🇸🇬

Singapore General Hospital, Outram Park, Singapore

RA Effect on Cell Surface Molecules in Vivo

Phase 1
Withdrawn
Conditions
HIV Infections
Interventions
First Posted Date
2018-11-27
Last Posted Date
2020-03-04
Lead Sponsor
Ottawa Hospital Research Institute
Registration Number
NCT03753867

Pharmacogenomics Study on Treatment of Psoriasis Vulgaris by Acitretin Capsules

Phase 2
Conditions
Psoriasis Vulgaris
Interventions
First Posted Date
2016-03-22
Last Posted Date
2016-03-22
Lead Sponsor
Central South University
Target Recruit Count
500
Registration Number
NCT02715960
Locations
🇨🇳

Xiangya Hospital Central South University, Changsha, Hunan, China

Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation

Completed
Conditions
Psoriasis
Inflammation
Interventions
Other: UVB Excimer Laser
Other: Narrowband UVB
First Posted Date
2015-01-01
Last Posted Date
2017-10-13
Lead Sponsor
University Hospitals Cleveland Medical Center
Target Recruit Count
26
Registration Number
NCT02330380
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

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