Acitretin

Generic Name
Acitretin
Brand Names
Soriatane
Drug Type
Small Molecule
Chemical Formula
C21H26O3
CAS Number
55079-83-9
Unique Ingredient Identifier
LCH760E9T7
Background

An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.

Indication

For the treatment of severe psoriasis in adults.

Associated Conditions
Keratinization disorders, Severe Psoriasis
Associated Therapies
-

Systemic Treatment Options for Generalized Lichen Planus

Phase 2
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-12-18
Last Posted Date
2024-12-18
Lead Sponsor
Sheikh Zayed Medical College
Target Recruit Count
124
Registration Number
NCT06739551
Locations
🇵🇰

Sheikh zayed Medical College and Hospital, Rahim Yar Khan, Punjab, Pakistan

Omentin-1 Level in Psoriatic Patients Treated With Narrowband Ultraviolet B Phototherapy Versus Acitretin

First Posted Date
2022-01-24
Last Posted Date
2022-01-24
Lead Sponsor
Mahmoud Ahmed Ali Ahmed
Target Recruit Count
60
Registration Number
NCT05203354
Locations
🇪🇬

Faculty of medicine - Aswan university, Aswan, Egypt

Outcomes With Treatment and Withdraw of Ixekizumab in Patients With Plaque Psoriasis

First Posted Date
2020-09-03
Last Posted Date
2022-11-25
Lead Sponsor
Singapore General Hospital
Target Recruit Count
40
Registration Number
NCT04537689
Locations
🇸🇬

Singapore General Hospital, Outram Park, Singapore

Combined Effect of Acitretin and Narrow Band Ultraviolet B on Vitiligo Repigmentation

First Posted Date
2020-01-28
Last Posted Date
2021-07-22
Lead Sponsor
Cairo University
Target Recruit Count
20
Registration Number
NCT04245319
Locations
🇪🇬

Cairo University, Cairo, Egypt

Outcomes With Treatment and Withdraw of Secukinumab in Patients With Plaque Psoriasis

First Posted Date
2020-01-27
Last Posted Date
2022-11-25
Lead Sponsor
Singapore General Hospital
Target Recruit Count
40
Registration Number
NCT04239859
Locations
🇸🇬

Singapore General Hospital, Outram Park, Singapore

RA Effect on Cell Surface Molecules in Vivo

Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2018-11-27
Last Posted Date
2020-03-04
Lead Sponsor
Ottawa Hospital Research Institute
Registration Number
NCT03753867

Comparative Effectiveness of Psoriasis Treatments on Systemic Inflammation

First Posted Date
2015-01-01
Last Posted Date
2017-10-13
Lead Sponsor
University Hospitals Cleveland Medical Center
Target Recruit Count
26
Registration Number
NCT02330380
Locations
🇺🇸

University Hospitals Cleveland Medical Center, Cleveland, Ohio, United States

Addition of Excimer Laser to Treatment With Acitretin Tablets for Psoriasis of the Palms and Soles

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2014-07-04
Last Posted Date
2021-03-10
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
2
Registration Number
NCT02181790
Locations
🇺🇸

Icahn School of Medicine at Mount Sinai, New York, New York, United States

A Phase II Study of Vemurafenib Combined With Acitretin in Patients With Advanced Melanoma

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2014-01-30
Last Posted Date
2018-12-26
Lead Sponsor
University of Arizona
Target Recruit Count
2
Registration Number
NCT02050321
Locations
🇺🇸

University of Arizona Cancer Center, Tucson, Arizona, United States

Economic Evaluation of Systemic Treatments for Moderate-to-severe Psoriasis

Completed
Conditions
First Posted Date
2013-03-18
Last Posted Date
2017-08-11
Lead Sponsor
Jochen Schmitt.
Target Recruit Count
1
Registration Number
NCT01812954
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