Sevoflurane
- Generic Name
- Sevoflurane
- Brand Names
- Sevorane, Sojourn, Ultane
- Drug Type
- Small Molecule
- Chemical Formula
- C4H3F7O
- CAS Number
- 28523-86-6
- Unique Ingredient Identifier
- 38LVP0K73A
- Background
Sevoflurane is an ether inhalation anesthetic agent used to induce and maintain general anesthesia. It is a volatile, non-flammable compound with a low solubility profile and blood/gas partition coefficient. Sevoflurane was patented in 1972, was approved for clinical use in Japan in 1990, and approved by the FDA in 1996. Sevoflurane is three times more poten...
- Indication
Sevoflurane is used for the induction and maintenance of general anesthesia in adult and pediatric patients for inpatient and outpatient surgery.
- Associated Conditions
- -
- Associated Therapies
- General Anesthesia, Induction and Maintenance of General Anesthesia
Intraoperative Bleeding During Endoscopic Sinus Surgery
- First Posted Date
- 2009-11-17
- Last Posted Date
- 2014-02-14
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 33
- Registration Number
- NCT01014728
- Locations
- 🇺🇸
The University of Chicago, Chicago, Illinois, United States
Anesthetic Effects in Mitochondrial Disease
- First Posted Date
- 2009-10-26
- Last Posted Date
- 2015-03-09
- Lead Sponsor
- d sessler
- Target Recruit Count
- 55
- Registration Number
- NCT01001585
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
Markers of Liver Apoptosis After Anesthesia With Sevoflurane or Propofol
- First Posted Date
- 2009-10-23
- Last Posted Date
- 2017-05-19
- Lead Sponsor
- University of Athens
- Target Recruit Count
- 67
- Registration Number
- NCT01000337
- Locations
- 🇬🇷
Aretaieio Hospital, University of Athens, Athens, Attiki, Greece
Ischemia/Reperfusion Injury of Human Endothelium: Role of Glucose and Statins
- Conditions
- Interventions
- First Posted Date
- 2009-10-15
- Last Posted Date
- 2015-03-17
- Lead Sponsor
- US Department of Veterans Affairs
- Target Recruit Count
- 59
- Registration Number
- NCT00995670
- Locations
- 🇺🇸
Zablocki VA Medical Center, Milwaukee, Milwaukee, Wisconsin, United States
Study of Efficacy, Pharmacokinetics and Safety of Continuous Intravenous Infusion of Org 9426 (Study P05977)
- Conditions
- Interventions
- First Posted Date
- 2009-10-02
- Last Posted Date
- 2015-05-12
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 38
- Registration Number
- NCT00988520
Study of Efficacy, Pharmacokinetics, and Safety of Bolus Maintenance Doses of Org 9426 (Study P05976)(COMPLETED)
- Conditions
- Interventions
- First Posted Date
- 2009-09-25
- Last Posted Date
- 2015-05-12
- Lead Sponsor
- Merck Sharp & Dohme LLC
- Target Recruit Count
- 40
- Registration Number
- NCT00984633
Pain After Laparoscopic Cholecystectomy
- Conditions
- Interventions
- First Posted Date
- 2009-09-24
- Last Posted Date
- 2019-02-01
- Lead Sponsor
- Baylor College of Medicine
- Target Recruit Count
- 80
- Registration Number
- NCT00983918
- Locations
- 🇺🇸
Ben Taub General Hospital, Houston, Texas, United States
Organ Protection With Sevoflurane Postconditioning After Cardiac Surgery With Cardiopulmonary Bypass
- Conditions
- Interventions
- First Posted Date
- 2009-06-18
- Last Posted Date
- 2011-10-12
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 120
- Registration Number
- NCT00924222
Conditioning With Volatile Anesthetics in Liver Transplantation
- Conditions
- Interventions
- First Posted Date
- 2009-06-04
- Last Posted Date
- 2012-11-27
- Lead Sponsor
- University of Zurich
- Target Recruit Count
- 98
- Registration Number
- NCT00913276
- Locations
- 🇨🇭
University Hospital Zurich, Division of Anaesthesiology, Zurich, ZH, Switzerland
Emergence Delirium in Children: Total Intravenous Anesthesia With Propofol and Remifentanil Versus Inhalational Sevoflurane Anesthesia
- First Posted Date
- 2009-04-22
- Last Posted Date
- 2017-07-05
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 112
- Registration Number
- NCT00885443
- Locations
- 🇨🇦
British Columbia Children's Hospital, Vancouver, British Columbia, Canada
Drug Development Updates
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