NCT00924222CompletedNot Applicable
Organ Protection With Sevoflurane Postconditioning After Cardiac Surgery With Cardiopulmonary Bypass
Conditions
Interventions
Drugs
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- University of Zurich
- Enrollment
- 120
- Primary Endpoint
- Myocardial injury markers (myoglobin, creatine kinase, myocard specific creatine kinase, and troponin T)
Study Overview
Brief Summary
Organ protection, volatile anesthetics, postconditioning.
Sedation of patients on ICU after cardiac surgery with cardiopulmonary bypass with either propofol or sevoflurane. Evaluation of organ function and inflammatory mediators in the blood.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to 90 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Arms & Interventions
Sevoflurane
Experimental
Intervention: Sevoflurane (Drug)
Sevoflurane
Experimental
Intervention: Propofol (Drug)
Propofol
Experimental
Intervention: Sevoflurane (Drug)
Propofol
Experimental
Intervention: Propofol (Drug)
Outcomes
Primary Outcomes
Myocardial injury markers (myoglobin, creatine kinase, myocard specific creatine kinase, and troponin T)
Time Frame: Start and end of ICU stay
Secondary Outcomes
- Oxygenation index, postoperative pulmonary complications, ICU stay (days), length of hospitalisation(Start with surgery until end of hospitalisation)
Investigators
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