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Clinical Trials/NCT00924222
NCT00924222
Completed
Not Applicable

Organ Protection With Sevoflurane Postconditioning After Cardiac Surgery With Cardiopulmonary Bypass

University of Zurich0 sites120 target enrollmentOctober 2007
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ConditionsCardiac On-pump Surgery
InterventionsSevofluranePropofol
DrugsSevofluranePropofol

Overview

Phase
Not Applicable
Intervention
Sevoflurane
Conditions
Cardiac On-pump Surgery
Sponsor
University of Zurich
Enrollment
120
Primary Endpoint
Myocardial injury markers (myoglobin, creatine kinase, myocard specific creatine kinase, and troponin T)
Status
Completed
Last Updated
14 years ago
OverviewInvestigatorsEligibility CriteriaArms & InterventionsOutcomesSimilar Trials

Overview

Brief Summary

Organ protection, volatile anesthetics, postconditioning.

Sedation of patients on ICU after cardiac surgery with cardiopulmonary bypass with either propofol or sevoflurane. Evaluation of organ function and inflammatory mediators in the blood.

Registry
clinicaltrials.gov
Start Date
October 2007
End Date
December 2009
Last Updated
14 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Not provided

Exclusion Criteria

  • Not provided

Arms & Interventions

Sevoflurane

Intervention: Sevoflurane

Sevoflurane

Intervention: Propofol

Propofol

Intervention: Sevoflurane

Propofol

Intervention: Propofol

Outcomes

Primary Outcomes

Myocardial injury markers (myoglobin, creatine kinase, myocard specific creatine kinase, and troponin T)

Time Frame: Start and end of ICU stay

Secondary Outcomes

  • Oxygenation index, postoperative pulmonary complications, ICU stay (days), length of hospitalisation(Start with surgery until end of hospitalisation)

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