Hydrocortisone
- Generic Name
- Hydrocortisone
- Brand Names
- Ala-cort, Ala-scalp, Alcortin, Alkindi, Anusol HC, Aquanil HC, Casporyn HC, Cipro, Cipro HC, Colocort, Cortaid, Cortane-B, Cortef, Cortenema, Cortisporin, Cortizone-10, Dermacort, Dermarest Eczema, Dermazene, Home Papkit, Hydroskin, Monistat Itch Relief, Neosporin Eczema, Preparation H Hydrocortisone, Procto-med, Procto-pak, Proctocort, Proctol, Proctosedyl, Proctosol, Proctozone HC, Scalpicin Itch Relief, Texacort, Vanoxide-HC, Xerese, Plenadren, Efmody
- Drug Type
- Small Molecule
- Chemical Formula
- C21H30O5
- CAS Number
- 50-23-7
- Unique Ingredient Identifier
- WI4X0X7BPJ
- Background
Hydrocortisone, or cortisol, is a glucocorticoid secreted by the adrenal cortex. Hydrocortisone is used to treat immune, inflammatory, and neoplastic conditions. It was discovered in the 1930s by Edward Kendall and named Compound F, or 17-hydroxycorticosterone.
Hydrocortisone was granted FDA approval on 5 August 1952.
- Indication
Otic solutions are indicated for infections of the external auditory canal caused by susceptible organisms and with inflammation. Hydrocortisone tablets are indicated for certain endocrine, rheumatic, collagen, allergic, ophthalmic, respiratory, hematologic, neoplastic, edematous, gastrointestinal, and other conditions. A hydrocortisone enema is indicated fo...
- Associated Conditions
- Acute Gouty Arthritis, Acute Leukemia, Acute Otitis Externa, Adrenal Insufficiency, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Choroiditis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Crohn's Disease (CD), Dermatitis, Dermatomyositis (DM), Dermatosis, Drug hypersensitivity reaction, Epicondylitis, Erythroblastopenia, Fissure;Anal, Haemorrhoids, Herpes Labialis, Hypercalcemia of Malignancy, Immune Thrombocytopenia (ITP), Infection of the Fenestration Cavity, Infection of the Mastoidectomy Cavity, Iridocyclitis, Iritis, Itching caused by Hemorrhoids, Itching of the Anus, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Lymphomas NEC, Mycosis Fungoides (MF), Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Hemorrhoids, Pemphigus, Posterior Uveitis, Posttraumatic Osteoarthritis, Primary adrenocortical insufficiency, Proctitis, Proteinuria, Pruritis of the skin, Psoriatic Arthritis, Rectal inflammations NEC, Rheumatic heart disease, unspecified, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Skin Diseases, Stevens-Johnson Syndrome, Synovitis, Systemic Lupus Erythematosus, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Tenosynovitis, Acute rheumatic carditis, Anterior eye segment inflammation, Cryptitis, Disseminated Pulmonary Tuberculosis (TB), Exfoliative erythroderma, Fulminating Pulmonary Tuberculosis, Non-suppurative Thyroiditis, Severe Erythema multiforme, Severe Psoriasis, Subacute Bursitis, Superficial infection of the external auditory canal with inflammation, Symptomatic Sarcoidosis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
Chemotherapy With Liposomal Cytarabine CNS Prophylaxis for Adult Acute Lymphoblastic Leukemia & Lymphoblastic Lymphoma
- First Posted Date
- 2014-01-23
- Last Posted Date
- 2022-05-02
- Lead Sponsor
- University of California, San Diego
- Target Recruit Count
- 31
- Registration Number
- NCT02043587
- Locations
- 🇺🇸
UCSD, Division of Blood and Marrow Transplantation, Moores Cancer Center, La Jolla, California, United States
🇺🇸Hematological Malignancies/Stem Cell Transplantation Unit, David Geffen School of Medicine at UCLA, Los Angeles, California, United States
🇺🇸University of California Davis Comprehensive Cancer Center, Sacramento, California, United States
Steroid Use in Pediatric Fluid and Vasoactive Infusion Dependent Shock - Pilot Study
- First Posted Date
- 2014-01-23
- Last Posted Date
- 2019-03-26
- Lead Sponsor
- Children's Hospital of Eastern Ontario
- Target Recruit Count
- 57
- Registration Number
- NCT02044159
- Locations
- 🇨🇦
Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada
🇨🇦Hospital St. Justine, Montreal, Quebec, Canada
🇨🇦McMaster Children's Hospital, Hamilton, Ontario, Canada
Hydrocortisone for Term Hypotension
- Conditions
- Interventions
- First Posted Date
- 2013-10-01
- Last Posted Date
- 2021-07-06
- Lead Sponsor
- NICHD Neonatal Research Network
- Target Recruit Count
- 12
- Registration Number
- NCT01954056
- Locations
- 🇺🇸
Case Western Reserve University, Cleveland, Ohio, United States
🇺🇸Research Institute at Nationwide Children's Hospital, Columbus, Ohio, United States
🇺🇸University of Texas Health Science Center at Houston, Houston, Texas, United States
Effect of Cortisol on Physical Exertion in Patients With Primary Adrenal Failure
- First Posted Date
- 2013-05-07
- Last Posted Date
- 2013-12-02
- Lead Sponsor
- Haukeland University Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT01847690
- Locations
- 🇳🇴
Haukeland Universitetessykehus, Department of Medicine, Bergen, Norway
Vilazodone for Corticosteroid-Induced Memory Impairment
- Conditions
- Interventions
- First Posted Date
- 2013-04-10
- Last Posted Date
- 2019-04-11
- Lead Sponsor
- University of Texas Southwestern Medical Center
- Target Recruit Count
- 24
- Registration Number
- NCT01828515
- Locations
- 🇺🇸
UT Southwestern Medical Center, Dallas, Texas, United States
Effect of Low Dose Corticosteroids on Perioperative Markers of Thrombosis and Fibrinolysis in Total Knee Arthroplasty
- First Posted Date
- 2013-03-21
- Last Posted Date
- 2022-04-14
- Lead Sponsor
- Hospital for Special Surgery, New York
- Target Recruit Count
- 60
- Registration Number
- NCT01815918
- Locations
- 🇺🇸
Hospital for Special Surgery, New York, New York, United States
Effect of Steroids on Thrombosis (Blood Clot Formation) and Inflammation in Patients Undergoing Hip Surgery
- Conditions
- Interventions
- First Posted Date
- 2013-02-04
- Last Posted Date
- 2017-01-05
- Lead Sponsor
- Hospital for Special Surgery, New York
- Target Recruit Count
- 40
- Registration Number
- NCT01782859
- Locations
- 🇺🇸
Hospital for Special Surgery, New York, New York, United States
Continuous Subcutaneous Hydrocortisone Infusion in Congenital Adrenal Hyperplasia
- Conditions
- Interventions
- First Posted Date
- 2013-01-18
- Last Posted Date
- 2016-12-21
- Lead Sponsor
- Haukeland University Hospital
- Target Recruit Count
- 20
- Registration Number
- NCT01771328
- Locations
- 🇳🇴
Haukeland Universitetssykehus, Department of Medicine, Bergen, Norway
Sensitivity of Short and Long Allele Carriers of the 5-HTTLPR to Environmental Threat Post Hydrocortisone Administration
- First Posted Date
- 2012-10-19
- Last Posted Date
- 2015-03-20
- Lead Sponsor
- University of Texas at Austin
- Target Recruit Count
- 120
- Registration Number
- NCT01710202
- Locations
- 🇺🇸
University of Texas at Austin Department of Psychology, Austin, Texas, United States
🇺🇸University of Texas at Austin, Austin, Texas, United States
A Trial of Temsirolimus With Etoposide and Cyclophosphamide in Children With Relapsed Acute Lymphoblastic Leukemia and Non-Hodgkins Lymphoma
- First Posted Date
- 2012-06-07
- Last Posted Date
- 2023-07-27
- Target Recruit Count
- 16
- Registration Number
- NCT01614197
- Locations
- 🇺🇸
Childrens Hospital Los Angeles, Los Angeles, California, United States
🇺🇸Children's Healthcare of Atlanta, Emory University, Atlanta, Georgia, United States
🇺🇸Lurie Children's Hospital, Chicago, Illinois, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.