Prochlorperazine
- Generic Name
- Prochlorperazine
- Brand Names
- Compazine, Compro
- Drug Type
- Small Molecule
- Chemical Formula
- C20H24ClN3S
- CAS Number
- 58-38-8
- Unique Ingredient Identifier
- YHP6YLT61T
- Background
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. It mainly works by depressing the chemoreceptor trigger zone and blo...
- Indication
主要用于精神障碍，亦用于治疗严重的恶心、呕吐。
- Associated Conditions
- Acute Migraine, Schizophrenia, Tension Headache, Non-psychotic generalized anxiety, Severe Nausea and vomiting
- Associated Therapies
- -
Prochlorperazine Maleate Versus Placebo for the Prophylaxis of Acute Mountain Sickness
- Conditions
- Interventions
- First Posted Date
- 2024-06-10
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 62
- Registration Number
- NCT06450899
- Locations
- 🇺🇸
Mount Blue Sky, Evergreen, Colorado, United States
Intravenous Fluids in Pediatric Migraine
- Conditions
- Interventions
- First Posted Date
- 2023-12-26
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- Dayton Children's Hospital
- Target Recruit Count
- 134
- Registration Number
- NCT06182098
- Locations
- 🇺🇸
Dayton Children's Hosptial, Dayton, Ohio, United States
Intranasal Ketorolac Trial
- Conditions
- Interventions
- First Posted Date
- 2023-10-16
- Last Posted Date
- 2024-07-24
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 120
- Registration Number
- NCT06083571
- Locations
- 🇺🇸
Washington University in St. Louis, Saint Louis, Missouri, United States
Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple Myeloma
- Conditions
- Interventions
- First Posted Date
- 2021-08-19
- Last Posted Date
- 2024-04-02
- Lead Sponsor
- Koen van Besien
- Registration Number
- NCT05013437
- Locations
- 🇺🇸
University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center, Cleveland, Ohio, United States
Olanzapine for the Prevention of Chemotherapy Induced Nausea and Vomiting in Gynecologic Oncology Patients
- Conditions
- Interventions
- First Posted Date
- 2020-08-07
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- University of Michigan Rogel Cancer Center
- Target Recruit Count
- 62
- Registration Number
- NCT04503668
- Locations
- 🇺🇸
University of Michigan Rogel Cancer Center, Ann Arbor, Michigan, United States
Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve Gastrectomy
- Conditions
- Interventions
- First Posted Date
- 2018-02-15
- Last Posted Date
- 2024-02-14
- Lead Sponsor
- Stony Brook University
- Target Recruit Count
- 83
- Registration Number
- NCT03435003
- Locations
- 🇺🇸
Stony Brook University Hospital, Stony Brook, New York, United States
Netupitant/Palonosetron Hydrochloride and Dexamethasone With or Without Prochlorperazine or Olanzapine in Improving Chemotherapy-Induced Nausea and Vomiting in Patients With Breast Cancer
- First Posted Date
- 2017-12-08
- Last Posted Date
- 2024-04-26
- Lead Sponsor
- University of Rochester NCORP Research Base
- Target Recruit Count
- 1351
- Registration Number
- NCT03367572
- Locations
- 🇺🇸
Health Partners Inc, Minneapolis, Minnesota, United States
🇺🇸Hawaii MU NCORP, Honolulu, Hawaii, United States
🇺🇸Decatur Memorial Hospital, Decatur, Illinois, United States
Buccal Prochlorperazine Versus Intravenous Prochlorperazine for Migraine Headaches, a RCT
- First Posted Date
- 2016-05-23
- Last Posted Date
- 2018-01-05
- Target Recruit Count
- 80
- Registration Number
- NCT02779959
- Locations
- 🇺🇸
Harbor-UCLA Medical Center, Torrance, California, United States
The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine
- First Posted Date
- 2016-04-12
- Last Posted Date
- 2024-03-04
- Lead Sponsor
- Mike O'Callaghan Military Hospital
- Target Recruit Count
- 5
- Registration Number
- NCT02735343
- Locations
- 🇺🇸
Mike O'Callaghan Federal Medical Center, Nellis Air Force Base, Nevada, United States
The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine
- Conditions
- Interventions
- First Posted Date
- 2016-01-15
- Last Posted Date
- 2017-12-11
- Lead Sponsor
- University Medical Center of Southern Nevada
- Target Recruit Count
- 54
- Registration Number
- NCT02657031
- Locations
- 🇺🇸
University Medical Center of Southern Nevada, Las Vegas, Nevada, United States
Drug Development Updates
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