Prochlorperazine
- Generic Name
- Prochlorperazine
- Brand Names
- Compazine, Compro
- Drug Type
- Small Molecule
- Chemical Formula
- C20H24ClN3S
- CAS Number
- 58-38-8
- Unique Ingredient Identifier
- YHP6YLT61T
- Background
Prochlorperazine, also known as compazine, is a piperazine phenothiazine and first-generation antipsychotic drug that is used for the treatment of severe nausea and vomiting, as well as short-term management of psychotic disorders such as generalized non-psychotic anxiety and schizophrenia. It mainly works by depressing the chemoreceptor trigger zone and blo...
- Indication
主要用于精神障碍，亦用于治疗严重的恶心、呕吐。
- Associated Conditions
- Acute Migraine, Schizophrenia, Tension Headache, Non-psychotic generalized anxiety, Severe Nausea and vomiting
- Associated Therapies
- -
Family Intervention in Recent Onset Schizophrenia Treatment (FIRST)
- Conditions
- Interventions
- Other: Caregiver psycho-education and skills trainingOther: Caregiver support available at the study siteDrug: Paliperidone palmitateDrug: ChlorpromazineDrug: DroperidolDrug: FluphenazineDrug: HaloperidolDrug: LoxapineDrug: PerphenazineDrug: PimozideDrug: ProchlorperazineDrug: ThiothixeneDrug: ThioridazineDrug: TrifluoperazineDrug: AripiprazoleDrug: AsenapineDrug: ClozapineDrug: IloperidoneDrug: OlanzapineDrug: PaliperidoneDrug: QuetiapineDrug: RisperidoneDrug: Ziprasidone
- First Posted Date
- 2015-11-09
- Last Posted Date
- 2019-01-23
- Lead Sponsor
- Janssen Scientific Affairs, LLC
- Target Recruit Count
- 296
- Registration Number
- NCT02600741
Hydromorphone Versus Prochlorperazine + Diphenhydramine for Acute Migraine
- Conditions
- Interventions
- First Posted Date
- 2015-03-17
- Last Posted Date
- 2018-08-31
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 127
- Registration Number
- NCT02389829
- Locations
- 🇺🇸
Montefiore Medical Center--Einstein, Bronx, New York, United States
Ondansetron vs Prochlorperazine for Nausea and Vomiting in the Emergency Department
- First Posted Date
- 2008-01-10
- Last Posted Date
- 2014-05-19
- Lead Sponsor
- Emory University
- Target Recruit Count
- 64
- Registration Number
- NCT00590317
- Locations
- 🇺🇸
Grady Hospital, Atlanta, Georgia, United States
🇺🇸Grady Memorial Hospital, Atlanta, Georgia, United States
Prevention of Delayed Nausea A Phase III Double-Blind Placebo-Controlled Clinical Trial
- Conditions
- Interventions
- First Posted Date
- 2007-05-17
- Last Posted Date
- 2015-11-10
- Lead Sponsor
- Joseph Roscoe
- Target Recruit Count
- 1021
- Registration Number
- NCT00475085
- Locations
- 🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States
🇺🇸CCOP - Central Illinois, Decatur, Illinois, United States
🇺🇸CCOP - Kalamazoo, Kalamazoo, Michigan, United States
Prochlorperazine vs Metoclopramide
- Conditions
- First Posted Date
- 2006-08-16
- Last Posted Date
- 2018-04-17
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 76
- Registration Number
- NCT00364806
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Comparison of Antiemetic Drugs in Preventing Delayed Nausea After Chemotherapy in Patients With Cancer
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2015-10-15
- Lead Sponsor
- Gary Morrow
- Registration Number
- NCT00020657
- Locations
- 🇺🇸
MBCCOP - Gulf Coast, Mobile, Alabama, United States
🇺🇸CCOP - Mayo Clinic Scottsdale Oncology Program, Scottsdale, Arizona, United States
🇺🇸CCOP - Central Illinois, Decatur, Illinois, United States
Drug Development Updates
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