Nifedipine
- Generic Name
- Nifedipine
- Brand Names
- Adalat, Afeditab CR, Nifediac, Nifedical, Procardia
- Drug Type
- Small Molecule
- Chemical Formula
- C17H18N2O6
- CAS Number
- 21829-25-4
- Unique Ingredient Identifier
- I9ZF7L6G2L
- Background
Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to nicardipine. Nifedipine was developed by Bayer and first described in the literature, along with other dihydropyridines, in 1972. Since nifedipine's development, second and third generation dihydropyridines have been developed with slower onsets and lo...
- Indication
Nifedipine capsules are indicated to treat vasospastic angina and chronic stable angina. Extended release tablets are indicated to treat vasospastic angina, chronic stable angina, and hypertension.
- Associated Conditions
- Achalasia, Chronic Stable Angina Pectoris, Fissure;Anal, Hypertension, Hypertensive Emergency, Premature Labour, Proctalgia, Pulmonary Edemas, Pulmonary Hypertension (PH), Raynaud's Phenomenon, Ureteral Calculus, Vasospastic Angina
- Associated Therapies
- -
Indomethacin Versus Nifedipine for Preterm Labor Tocolysis
- First Posted Date
- 2007-06-15
- Last Posted Date
- 2018-10-01
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 29
- Registration Number
- NCT00486824
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Prophylactic Effect of Nifedipine on Further Decline in Renal Function in Patients Undergoing Open-Heart Surgery
- Conditions
- First Posted Date
- 2005-10-26
- Last Posted Date
- 2006-12-22
- Lead Sponsor
- University of Oslo School of Pharmacy
- Target Recruit Count
- 20
- Registration Number
- NCT00244530
- Locations
- 🇳🇴
Rikshospitalet University Hospital, Oslo, Norway
Treatment of Supine Hypertension in Autonomic Failure
- Conditions
- Interventions
- Drug: PlaceboDrug: ClonidineDrug: Nitroglycerin transdermalDrug: Dipyridamole/ Aspirin (Aggrenox)Drug: Desmopressin (DDAVP)Drug: SildenafilDrug: NifedipineDrug: HydralazineDrug: HydrochlorothiazideDrug: BosentanDrug: DiltiazemDrug: EplerenoneDrug: guanfacineDietary Supplement: L-arginineDrug: captoprilDrug: carbidopaDrug: losartanDrug: metoprolol tartrateDrug: nebivolol hydrochlorideDrug: prazosin hydrochlorideDrug: tamsulosin hydrochlorideOther: Head-up tilt.Drug: aliskirenOther: Local heat stress
- First Posted Date
- 2005-09-22
- Last Posted Date
- 2017-10-13
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 152
- Registration Number
- NCT00223717
- Locations
- 🇺🇸
Vanderbilt University, Nashville, Tennessee, United States
Treatment Targets for Chronic Hypertension in Pregnancy
- Conditions
- First Posted Date
- 2005-09-19
- Last Posted Date
- 2017-01-30
- Lead Sponsor
- Weill Medical College of Cornell University
- Registration Number
- NCT00194974
- Locations
- 🇺🇸
The New York PresbyterianHospital-Weill Medical College of Cornell University, New York, New York, United States
Magnesium Sulfate Versus Nifedipine for the Acute Tocolysis of Preterm Labor: A Prospective, Randomized Trial
- Conditions
- Interventions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2018-11-19
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 192
- Registration Number
- NCT00185900
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Nifedipine vs Placebo for Maintenance Tocolysis of Preterm Labor.
- Conditions
- Interventions
- First Posted Date
- 2005-09-16
- Last Posted Date
- 2011-06-13
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 70
- Registration Number
- NCT00185952
- Locations
- 🇺🇸
Stanford University School of Medicine, Stanford, California, United States
Two Dose Regimens of Nifedipine for the Management of Preterm Labor
- First Posted Date
- 2005-08-30
- Last Posted Date
- 2013-07-19
- Lead Sponsor
- American University of Beirut Medical Center
- Target Recruit Count
- 102
- Registration Number
- NCT00137501
- Locations
- 🇱🇧
American University of Beirut Medical Center, Beirut, Lebanon
Congenital Adrenal Hyperplasia: Calcium Channels as Therapeutic Targets
- Conditions
- First Posted Date
- 1999-11-04
- Last Posted Date
- 2005-06-24
- Lead Sponsor
- National Center for Research Resources (NCRR)
- Registration Number
- NCT00000102
- Locations
- 🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States
Raynaud's Treatment Study (RTS)
- Conditions
Asymptomatic Cardiac Ischemia Pilot (ACIP) Study
- Conditions
Drug Development Updates
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