Lamivudine
- Generic Name
- Lamivudine
- Brand Names
- Cimduo, Combivir, Delstrigo, Dovato, Epivir, Epivir Hbv, Epzicom, Kivexa, Symfi, Triumeq, Trizivir, Zeffix, Lamivudine Teva Pharma B.V., Lamivudine Teva
- Drug Type
- Small Molecule
- Chemical Formula
- C8H11N3O3S
- CAS Number
- 134678-17-4
- Unique Ingredient Identifier
- 2T8Q726O95
- Background
A reverse transcriptase inhibitor and zalcitabine analog in which a sulfur atom replaces the 3' carbon of the pentose ring. It is used to treat Human Immunodeficiency Virus Type 1 (HIV-1) and hepatitis B (HBV).
- Indication
For the treatment of HIV infection and chronic hepatitis B (HBV).
- Associated Conditions
- Chronic Hepatitis B Infection, Human Immunodeficiency Virus (HIV) Infections, Human Immunodeficiency Virus Type 1 (HIV-1) Infection
- Associated Therapies
- -
Effects of Anti-HIV Therapy on Treatment for Hepatitis C in HCV/HIV Infected Adults
- Conditions
- First Posted Date
- 2005-01-04
- Last Posted Date
- 2021-11-01
- Target Recruit Count
- 2
- Registration Number
- NCT00100581
- Locations
- 🇺🇸
Columbia Univ., HIV Prevention and Treatment Medical Ctr., New York, New York, United States
🇺🇸Univ. of Texas Southwestern Med. Ctr., Amelia Court Continuity Clinic, Dallas, Texas, United States
Safety and Efficacy of Adefovir Dipivoxil in Children and Adolescents With Chronic Hepatitis B
- Conditions
- Interventions
- First Posted Date
- 2004-11-01
- Last Posted Date
- 2012-05-22
- Lead Sponsor
- Gilead Sciences
- Target Recruit Count
- 173
- Registration Number
- NCT00095121
Effectiveness of Directly Observed Therapy in Combined HIV and Tuberculosis Treatment in Resource-limited Settings
- Conditions
- First Posted Date
- 2004-09-21
- Last Posted Date
- 2010-03-29
- Target Recruit Count
- 592
- Registration Number
- NCT00091936
- Locations
- 🇿🇦
King Edward VIII Hospital, Congella, Durban, South Africa
🇿🇦Prince Cyril Zulu CDC, Congella, Durban, South Africa
KALETRA Or LEXIVA With Ritonavir Combined With EPIVIR And Abacavir In Naive Subjects Over 48 Weeks
- Conditions
- First Posted Date
- 2004-06-21
- Last Posted Date
- 2011-05-16
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 866
- Registration Number
- NCT00085943
- Locations
- 🇨🇭
GSK Investigational Site, St Gallen, Switzerland
Strategies for Delivering Anti-HIV Therapy in South Africa
- Conditions
- First Posted Date
- 2004-04-07
- Last Posted Date
- 2007-09-18
- Target Recruit Count
- 813
- Registration Number
- NCT00080522
- Locations
- 🇿🇦
University of the Witwatersrand/Clinical HIV Research Unit, Johannesburg, Gauteng, South Africa
🇿🇦University of Cape Town/Masiphumelele, Cape Town, South Peninsula, South Africa
Anti-HIV Drugs for Ugandan Patients With HIV and Tuberculosis
- Conditions
- Interventions
- First Posted Date
- 2004-02-23
- Last Posted Date
- 2010-08-12
- Target Recruit Count
- 350
- Registration Number
- NCT00078247
- Locations
- 🇺🇬
Makerere University Medical School, Kampala, Uganda
Telbivudine Versus Lamivudine in Adults With Decompensated Chronic Hepatitis B and Evidence of Cirrhosis
- Conditions
- Interventions
- First Posted Date
- 2004-01-22
- Last Posted Date
- 2011-09-05
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 232
- Registration Number
- NCT00076336
- Locations
- 🇻🇳
Novartis, Hanoi, Vietnam
Preventing Sexual Transmission of HIV With Anti-HIV Drugs
- First Posted Date
- 2003-12-17
- Last Posted Date
- 2021-11-05
- Target Recruit Count
- 3526
- Registration Number
- NCT00074581
- Locations
- 🇺🇸
Fenway Community Health Ctr. CRS, Boston, Massachusetts, United States
🇧🇼Gaborone CRS, Gaborone, Botswana
🇧🇷Hospital Geral de Nova Iguaçu CRS (HGNI CRS), Nova Iguacu, Rio De Janeiro, Brazil
Combination Chemotherapy Followed By Antiviral Therapy and Interferon Alfa in Treating Patients With HTLV-1-Related Adult T-Cell Leukemia/Lymphoma
- Conditions
- First Posted Date
- 2003-01-27
- Last Posted Date
- 2016-02-03
- Lead Sponsor
- AIDS Malignancy Consortium
- Target Recruit Count
- 19
- Registration Number
- NCT00041327
- Locations
- 🇺🇸
USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States
🇺🇸University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida, United States
🇺🇸Siteman Cancer Center at Barnes-Jewish Hospital, Saint Louis, Missouri, United States
Treatment of Hepatitis B Virus (HBV) Before Beginning Anti-HIV Drugs in Patients With Both HBV and HIV
- Conditions
- Interventions
Drug Development Updates
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