Iodide I-123
- Generic Name
- Iodide I-123
- Drug Type
- Small Molecule
- Chemical Formula
- I
- CAS Number
- 69239-56-1
- Unique Ingredient Identifier
- 98QPV8670C
- Background
Iodide I-123 (as sodium Iodide I-123) is a radioactive isotope of iodine used in nuclear medicine for the diagnostic study of thyroid disease. Following oral administration, I-123 is absorbed through the gastrointestinal tract and is taken up by the thyroid gland. After incorporation, a gamma camera is used to detect the decay by electron capture to tellurium-123.
Iodine is commonly used in thyroid function diagnostic tests as this gland normally absorbs iodine through the diet for formation of the thyroid hormones triiodothyronine (T3) and its prohormone, thyroxine (T4). Radioactive I-123 in particular is effective for this use as its half-life of approximately 13.13 h (hours) is ideal for the 24-h (hour) iodine uptake test and it has a reduced radiation burden as compared to I-131.
- Indication
Administration of Sodium Iodide I 123 Capsules is indicated as a diagnostic procedure to be used in evaluating thyroid function and/or morphology.
- Associated Conditions
- Thyroid cancer metastases
Minimize Radioactive Iodine Ablation Of Remnant Thyroid in Differentiated Thyroid Cancer
- First Posted Date
- 2015-04-16
- Last Posted Date
- 2017-01-20
- Lead Sponsor
- National Cancer Center, Korea
- Target Recruit Count
- 556
- Registration Number
- NCT02418247
- Locations
- π°π·
Chungnam National University Hospital, Daejun, Korea, Republic of
π°π·National Cancer Center, Korea, Goyang, Korea, Republic of
π°π·Seoul National University Boramae Medical Center, Seoul, Korea, Republic of
Serotonin Transporter Density in Late-life Depression With and Without Dementia
- First Posted Date
- 2012-03-08
- Last Posted Date
- 2016-01-28
- Lead Sponsor
- Chang Gung Memorial Hospital
- Target Recruit Count
- 39
- Registration Number
- NCT01548937
DaTSCAN Imaging in Aging and Neurodegenerative Disease
- Conditions
- REM Sleep Behavior DisorderDementiaParkinsonismMild Cognitive Impairment
- Interventions
- Device: Single photon emission computed tomography (SPECT) scan
- First Posted Date
- 2011-10-17
- Last Posted Date
- 2025-03-25
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 500
- Registration Number
- NCT01453127
- Locations
- πΊπΈ
Mayo Clinic, Rochester, Minnesota, United States
Pathogenesis of Stress-Induced Cardiomyopathy by I-123 MIBG
- Conditions
- Stress Induced Cardiomyopathy
- Interventions
- First Posted Date
- 2011-09-13
- Last Posted Date
- 2016-03-22
- Lead Sponsor
- University of Pittsburgh
- Target Recruit Count
- 10
- Registration Number
- NCT01432626
- Locations
- πΊπΈ
University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States
Study Dosed With (123I-mIBG) for Identifying Subjects With Heart Failure Who Will Experience an Adverse Cardiac Event
- First Posted Date
- 2008-11-05
- Last Posted Date
- 2017-04-26
- Lead Sponsor
- GE Healthcare
- Target Recruit Count
- 471
- Registration Number
- NCT00785044
- Locations
- πΊπΈ
GE Healthcare, Princeton, New Jersey, United States
Comparison of I-124 PET/CT, F-18 FDG PET/CT & I-123 Whole Body Scintigraphy for Recurrent Thyroid CA
- Conditions
- Thyroid Cancer
- First Posted Date
- 2006-09-08
- Last Posted Date
- 2022-06-21
- Lead Sponsor
- Stanford University
- Registration Number
- NCT00373711
Drug Development Updates
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