Zinc sulfate

Generic Name: Zinc sulfate

Brand Names: Anodan-HC, Anusol, Egozinc, Multitrace-4, Multitrace-5, Proctodan-HC, Rectogel, Riva-sol HC, Tandem Plus

Drug Type: Small Molecule

Chemical Formula: O_₄SZn

CAS Number: 7733-02-0

Unique Ingredient Identifier: 0J6Z13X3WO

Background: Zinc sulfate is the inorganic compound with the formula ZnSO4 and historically known as "white vitriol". It is on the World Health Organization's List of Essential Medicines, a list of the most important medication needed in a basic health system.

Indication: This medication is a mineral used to treat or prevent low levels of zinc alone and together with oral rehydration therapy (ORT). It is also used as a topical astringent. Zinc Sulfate Injection, USP is indicated for use as a supplement to intravenous solutions given for TPN.

Associated Conditions: Dry Eyes, Local itching, Localized pain, Localized swelling

Associated Therapies: Nutritional supplementation

Clinical Trials

Zinc Supplementation on Very Low Birth Weight Infant

Phase 4

Conditions: Early-Onset Sepses, Neonatal
Periventricular Haemorrhage Neonatal
Bronchopulmonary Dysplasia
Retinopathy of Prematurity
Enterocolitis, Necrotizing
Small for Gestational Age Infant

Interventions: Drug: Placebos
Drug: Zinc Sulfate

First Posted Date: 2019-08-08

Last Posted Date: 2019-08-15

Lead Sponsor: Fakultas Kedokteran Universitas Indonesia

Target Recruit Count: 364

Registration Number: NCT04050488

The Effect of Zinc on the Gingival Crevicular Fluid Level of Total Oxidant Capacity in Type 2 Diabetic Patients

Not Applicable

Conditions: Chronic Periodontitis

Interventions: Procedure: scaling and root planing
Drug: Zinc Sulfate

First Posted Date: 2019-04-23

Last Posted Date: 2019-04-23

Lead Sponsor: Cairo University

Target Recruit Count: 34

Registration Number: NCT03923829

Immunomodulation by Zinc Supplementation in Children With Pneumonia

Phase 1

Completed

Conditions: Pneumonia
Children, Only

Interventions: Other: Glucose
Drug: Zinc sulfate

First Posted Date: 2018-10-01

Last Posted Date: 2018-10-01

Lead Sponsor: Universidad Nacional Autonoma de Mexico

Target Recruit Count: 103

Registration Number: NCT03690583

Locations: 🇲🇽
Hospital General de Mexico, Mexico, Mexico
🇲🇽
Hospital Pediatrico de Coyoacan, Mexico city, Ciudad De México, Mexico

Intralesional Candidal Antigen Versus Intralesional Zinc Sulphate in Treatment of Cutaneous Warts

Phase 3

Conditions: Warts

Interventions: Drug: Candida Antigen
Drug: Zinc Sulfate

First Posted Date: 2017-05-18

Last Posted Date: 2018-07-24

Lead Sponsor: Assiut University

Target Recruit Count: 70

Registration Number: NCT03158168

Locations: 🇪🇬
Assiut University Hospital, Assiut, Egypt

Zinc Supplementation on Cellular Immunity in Thalassemia Major

Phase 4

Completed

Conditions: Immunosuppression
Thalassemia
Splenectomy; Status

Interventions: Drug: Zinc Sulfate
Drug: Sucrose Syrup

First Posted Date: 2017-04-17

Last Posted Date: 2017-04-17

Lead Sponsor: Fakultas Kedokteran Universitas Indonesia

Target Recruit Count: 58

Registration Number: NCT03117192

Locations: 🇮🇩
Fakultas Kedokteran Universitas Indonesia, Jakarta Pusat, Jakarta, Indonesia

Effect of Zinc Supplementation on Appetite and Growth in Primary Malnourished Children

Phase 4

Conditions: Appetite Disorders

Interventions: Other: Placebo
Drug: Zinc sulphate

First Posted Date: 2017-04-04

Last Posted Date: 2017-04-04

Lead Sponsor: Ain Shams University

Target Recruit Count: 50

Registration Number: NCT03098810

Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis

Phase 2

Completed

Conditions: Acute Alcoholic Hepatitis

Interventions: Drug: Anakinra
Drug: Methylprednisolone
Drug: Pentoxifylline
Drug: Zinc Sulfate

First Posted Date: 2013-03-12

Last Posted Date: 2021-11-01

Lead Sponsor: Mack Mitchell

Target Recruit Count: 104

Registration Number: NCT01809132

Locations: 🇺🇸
University of Louisville, Louisville, Kentucky, United States
🇺🇸
University of Texas Southwestern Medical Center, Dallas, Texas, United States
🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States

and more 1 locations

Efficacy of Use of Zinc in the Treatment of Acute Diarrhea in Infants

Phase 4

Completed

Conditions: Acute Diarrhea
Acute Gastroenteritis

Interventions: Other: placebo
Drug: Zinc Sulfate

First Posted Date: 2012-04-05

Last Posted Date: 2013-05-07

Lead Sponsor: Centro Pediatrico Albina de Patino

Target Recruit Count: 52

Registration Number: NCT01571856

Locations: 🇧🇴
Centro Pediatrico Albina Patino, Cochabamba, Bolivia

Effect of Zinc Supplementation on Response to Oral Polio Vaccine in Infants in Pakistan

Not Applicable

Completed

Conditions: Poliomyelitis

Interventions: Other: Placebo
Drug: Zinc Sulfate

First Posted Date: 2010-10-28

Last Posted Date: 2021-02-18

Lead Sponsor: Aga Khan University

Target Recruit Count: 320

Registration Number: NCT01229579

Locations: 🇵🇰
Project Office, Aga Khan University, Matiari, Matiari, Sindh, Pakistan

Oral Zinc for the Treatment of Acute Diarrhea in US Children

Not Applicable

Completed

Conditions: Diarrhea
Gastroenteritis

Interventions: Drug: Placebo oral capsule
Drug: Zinc Sulfate

First Posted Date: 2010-09-10

Last Posted Date: 2018-08-22

Lead Sponsor: Boston Children's Hospital

Target Recruit Count: 71

Registration Number: NCT01198587

Locations: 🇺🇸
Children's Hospital Boston, Boston, Massachusetts, United States

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2025. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy