Sumatriptan
- Generic Name
- Sumatriptan
- Brand Names
- Imitrex, Onzetra, Sumavel, Tosymra, Treximet, Zembrace
- Drug Type
- Small Molecule
- Chemical Formula
- C14H21N3O2S
- CAS Number
- 103628-46-2
- Unique Ingredient Identifier
- 8R78F6L9VO
- Background
Sumatriptan is a serotonin receptor agonist commonly used to treat migraines and sometimes cluster headaches. Sumatriptan is the first of the triptans and was made available in Europe in 1991 to treat migraines. Sumatriptan was granted FDA approval on 28 December 1992.
- Indication
A combination sumatriptan and naproxen tablet is indicated for the treatment of migraines with or without auras in patients 12 years of age and older. Sumatriptan nasal powder, nasal spray, subcutaneous injection, and tablets are indicated to treat migraines with or without auras in adults. One of the subcutaneous formulations of sumatriptan is also indicate...
- Associated Conditions
- Acute Migraine, Acute Cluster headaches
- Associated Therapies
- -
Migraine Treatment Satisfaction With Treximet Versus Concomitant 2 Aleve and Imitrex
- First Posted Date
- 2011-10-13
- Last Posted Date
- 2011-10-13
- Lead Sponsor
- Stephen H. Landy, M.D.
- Target Recruit Count
- 50
- Registration Number
- NCT01450995
- Locations
- 🇺🇸
Wesley Headache Clinic, Memphis, Tennessee, United States
Dose Ranging Study of Rimegepant (BMS-927711) for the Acute Treatment of Migraine
- Conditions
- Interventions
- First Posted Date
- 2011-09-08
- Last Posted Date
- 2023-02-28
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 1026
- Registration Number
- NCT01430442
- Locations
- 🇺🇸
Broward Research Group, Pembroke Pines, Florida, United States
🇺🇸Clinical Res. Advantage Inc/ Desert Clinical Research Llc, Tempe, Arizona, United States
🇺🇸Tidewater Integrated Medical Research, Virginia Beach, Virginia, United States
Drug Use Investigation for IMIGRAN Tablet
- First Posted Date
- 2011-06-20
- Last Posted Date
- 2017-05-22
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 3571
- Registration Number
- NCT01376141
CGRP, Estrogen, Cortisol, VIP, α-Amylase, PGE2, PGI2 and ß-Endorphin Levels in Menstrual Migraine Before and After Treximet
- First Posted Date
- 2011-04-06
- Last Posted Date
- 2014-04-09
- Lead Sponsor
- Cady, Roger, M.D.
- Target Recruit Count
- 41
- Registration Number
- NCT01329562
- Locations
- 🇺🇸
Clinvest, Springfield, Missouri, United States
🇺🇸University Internal Medicine Associates, Inc., Cincinnati, Ohio, United States
Bioequivalence Study of Sumatriptan Succinate Tablets 100 mg in Fed Conditions
- First Posted Date
- 2011-01-04
- Last Posted Date
- 2011-01-04
- Lead Sponsor
- Dr. Reddy's Laboratories Limited
- Target Recruit Count
- 50
- Registration Number
- NCT01269281
- Locations
- 🇮🇳
BA Research India Limited, Bodakdev, Ahmedabad, India
Efficacy and Safety of Acetaminophen, Aspirin and Caffeine With Sumatriptan in the Acute Treatment of Migraine
- Conditions
- Interventions
- First Posted Date
- 2010-11-25
- Last Posted Date
- 2012-07-30
- Lead Sponsor
- Novartis
- Target Recruit Count
- 752
- Registration Number
- NCT01248468
Ictal and Interictal Inflammatory Markers in Migraine
- First Posted Date
- 2010-06-07
- Last Posted Date
- 2016-10-06
- Lead Sponsor
- Johns Hopkins University
- Target Recruit Count
- 36
- Registration Number
- NCT01138150
- Locations
- 🇺🇸
The Johns Hopkins Bayview Headache Center, Baltimore, Maryland, United States
Trial of Comprehensive Migraine Intervention
- Conditions
- Interventions
- First Posted Date
- 2010-02-19
- Last Posted Date
- 2018-08-31
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 50
- Registration Number
- NCT01071317
- Locations
- 🇺🇸
Montefiore Medical Center, Bronx, New York, United States
Sumatriptan and Naratriptan Pregnancy Registry
- Conditions
- Interventions
- First Posted Date
- 2010-02-01
- Last Posted Date
- 2014-11-02
- Lead Sponsor
- GlaxoSmithKline
- Target Recruit Count
- 868
- Registration Number
- NCT01059604
Evaluation of Treatment Satisfaction and Preference for Sumavel DosePro in the Treatment of Migraine
- First Posted Date
- 2009-11-20
- Last Posted Date
- 2011-12-29
- Lead Sponsor
- Zogenix, Inc.
- Target Recruit Count
- 246
- Registration Number
- NCT01016834
- Locations
- 🇺🇸
C. Phillip O'Carroll, MD, Inc, Newport Beach, California, United States
🇺🇸California Medical Clinic for Headache, Santa Monica, California, United States
🇺🇸Comprehensive Neurosciences Inc, Atlanta, Georgia, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.