Thiamine

Generic Name: Thiamine

Brand Names: Alertonic, Concept Ob, Fortaplex, Infuvite, Infuvite Pediatric, Irospan 24/6 Kit, Mvc-fluoride, Mvi Pediatric, Natafort, Neo-bex, Pregvit, Tandem Plus, Vitafol-one

Drug Type: Small Molecule

Chemical Formula: C_₁₂H_₁₇N_₄OS

CAS Number: 70-16-6

Unique Ingredient Identifier: 4ABT0J945J

Background: Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.

Indication: For the treatment of thiamine and niacin deficiency states, Korsakov's alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.

Associated Conditions: Anemia, B12 Deficiency Anemia, Beriberi, Cardiovascular Heart Disease caused by Thiamine Deficiency, Folic Acid Deficiency Anemia, Infantile Beriberi, Infection, Iron Deficiency (ID), Neuritis caused by Pregnancy, Secondary anemia, Thiamine Deficiency, Vitamin Deficiency, Wernicke's encephalopathy, Liver disorders

Associated Therapies: Nutritional supplementation, Vitamin supplementation, Dietary supplementation

Clinical Trials

Scientific Breakthroughs: New Products of Biotechnology

Since 1996, over 70 countries have engaged with biotech crops, focusing on yield, pest resistance, and herbicide tolerance. Recent innovations include GM bananas resistant to diseases, biofortified rice with high Vitamin B1, seedless blackberries, air-purifying bioengineered pothos, and golden lettuce with increased beta-carotene. These advancements aim to address agricultural challenges and nutritional deficiencies.

pmc.ncbi.nlm.nih.gov

3 years ago

Rapidly Progressive Dementia

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Thiamine

Scientific Breakthroughs: New Products of Biotechnology

Rapidly Progressive Dementia

Drug Development Updates