Sodium Thiosulfate
- Generic Name
- Sodium Thiosulfate
- Indication
⑴治疗氰化物中毒，与高铁血红蛋白形成剂联合应用；
⑵治疗降压药硝普钠过量中毒；
⑶治疗可溶性钡盐（如硝酸钡）中毒；
⑷治疗砷、汞、铋、铅等金属中毒，但首选二巯基类药物及依地酸类药物；
⑸作为非特异性抗炎药，用于皮炎、湿疹、荨麻疹、药物性皮炎、副银屑病的治疗【1.《糖皮质激素类药物临床应用指导原则》；2.《中西医结合系统药物治疗湿疹皮炎类皮肤病专家共识》2015；3.《临床诊疗指南皮肤病与性病分册》】。
Laparoscopic Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) for Metastatic Gastric Cancer
- Conditions
- Gastrointestinal Cancer
- Interventions
- First Posted Date
- 2014-03-20
- Last Posted Date
- 2021-06-15
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 21
- Registration Number
- NCT02092298
- Locations
- 🇺🇸
University of Texas MD Anderson Cancer Center, Houston, Texas, United States
A Pilot Study to Evaluate Topical Sodium Thiosulfate Therapy for Calcinosis Cutis
- First Posted Date
- 2013-08-08
- Last Posted Date
- 2016-11-17
- Lead Sponsor
- Loyola University
- Registration Number
- NCT01918904
Surgery and Heated Chemotherapy for Adrenocortical Carcinoma
- Conditions
- Peritoneal CarcinomatosisAdrenocortical Carcinoma
- Interventions
- First Posted Date
- 2013-04-17
- Last Posted Date
- 2019-07-30
- Lead Sponsor
- National Cancer Institute (NCI)
- Target Recruit Count
- 11
- Registration Number
- NCT01833832
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, 9000 Rockville Pike, Bethesda, Maryland, United States
Topical Sodium Thiosulfate and Fractional Carbon Dioxide Laser in Treating Dermatomyositis Associated Calcinosis
- Conditions
- Calcinosis
- Interventions
- Device: Fractionated Carbon Dioxide (FCO2) Laser
- First Posted Date
- 2012-04-06
- Last Posted Date
- 2017-11-29
- Lead Sponsor
- Alison Ehrlich
- Target Recruit Count
- 3
- Registration Number
- NCT01572844
- Locations
- 🇺🇸
The George Washington University Medical Faculty Associates Departments of Dermatology and Rheumatology, Washington, District of Columbia, United States
Effect of Sodium Thiosulfate on Urine Chemistries of Hypercalciuric Stone Formers
- First Posted Date
- 2010-03-17
- Last Posted Date
- 2013-12-24
- Lead Sponsor
- VA New York Harbor Healthcare System
- Target Recruit Count
- 10
- Registration Number
- NCT01088555
- Locations
- 🇺🇸
VA New York Harbor Healthcare System, New York, New York, United States
The Pharmacologic Profile of Sodium Thiosulfate in Renal Failure and Healthy Volunteers
- First Posted Date
- 2009-11-06
- Last Posted Date
- 2011-10-13
- Lead Sponsor
- Insel Gruppe AG, University Hospital Bern
- Target Recruit Count
- 19
- Registration Number
- NCT01008631
- Locations
- 🇨🇭
Department of Nephrology and Hypertension, University of Berne, Berne, Switzerland
Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors
- Conditions
- Germ Cell TumorRecurrent MedulloblastomaEmbryonal Tumor With Multilayered Rosettes, C19MC-AlteredMedulloblastomaMedulloepitheliomaRecurrent Malignant Germ Cell TumorRecurrent Primitive Neuroectodermal TumorPrimitive Neuroectodermal TumorCentral Nervous System Embryonal NeoplasmRecurrent Childhood Central Nervous System Embryonal Neoplasm
- Interventions
- Other: Quality-of-Life AssessmentOther: Questionnaire Administration
- First Posted Date
- 2009-09-24
- Last Posted Date
- 2021-10-26
- Lead Sponsor
- OHSU Knight Cancer Institute
- Target Recruit Count
- 17
- Registration Number
- NCT00983398
- Locations
- 🇺🇸
University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota, United States
🇺🇸OHSU Knight Cancer Institute, Portland, Oregon, United States
Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy
- Conditions
- Brain TumorChildhood Germ Cell TumorSarcomaCentral Nervous System TumorLiver CancerNeuroblastomaOvarian CancerExtragonadal Germ Cell TumorOtotoxicity
- Interventions
- Procedure: examination
- First Posted Date
- 2008-07-16
- Last Posted Date
- 2023-11-09
- Lead Sponsor
- Children's Oncology Group
- Target Recruit Count
- 131
- Registration Number
- NCT00716976
- Locations
- 🇺🇸
University of Illinois Cancer Center, Chicago, Illinois, United States
🇺🇸University of Miami Sylvester Comprehensive Cancer Center - Miami, Miami, Florida, United States
🇺🇸Rady Children's Hospital - San Diego, San Diego, California, United States
Cisplatin With or Without Sodium Thiosulfate in Treating Young Patients With Stage I, II, or III Childhood Liver Cancer
- Conditions
- Liver CancerOtotoxicity
- Interventions
- First Posted Date
- 2008-04-03
- Last Posted Date
- 2018-05-29
- Lead Sponsor
- University of Birmingham
- Target Recruit Count
- 116
- Registration Number
- NCT00652132
- Locations
- 🇬🇧
Southampton Children's Hospital, Southampton, United Kingdom
🇬🇧Royal Manchester Children's Hospital, Manchester, England, United Kingdom
🇬🇧Royal Hospital for Sick Children, Glasgow, Scotland, United Kingdom
Extrapleural Pneumonectomy /Pleurectomy Decortication, IHOC Cisplatin and Gemcitabine With Amifostine and Sodium Thiosulfate Cytoprotection for Resectable Malignant Pleural Mesothelioma
- Conditions
- Malignant Pleural Mesothelioma
- Interventions
- Procedure: Extrapleural pneumonectomy (EPP)Procedure: Pleurectomy/Decortication
- First Posted Date
- 2007-12-11
- Last Posted Date
- 2017-01-23
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 141
- Registration Number
- NCT00571298
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Drug Development Updates
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