Vitamin D3

Generic Name: Vitamin D3

Brand Names: Adrovance, Animi-3 With Vitamin D, Citranatal B-calm Kit, Citranatal Harmony, Fosamax Plus D, Fosavance, Infuvite, Infuvite Pediatric, Mvc-fluoride, Natafort, Pregvit, Vidextra

Drug Type: Small Molecule

Chemical Formula: C_₂₇H_₄₄O

CAS Number: 67-97-0

Unique Ingredient Identifier: 1C6V77QF41

Background: Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalcifero...

Indication: Cholecalciferol use is indicated for the treatment of specific medical conditions like refractory rickets (or vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia .
...

Associated Conditions: Bone Fractures, Calcium and Vitamin D Deficiencies, Deficiency of Vitamin D3, Deficiency, Vitamin A, Deficiency, Vitamin D, Hip Fracture, Hypoparathyroidism, Hypophosphatemia, Familial, Menopause, Osteomalacia, Osteoporosis, Postmenopausal Osteoporosis, Vertebral Fractures, Vitamin D Resistant Rickets, Vitamin Deficiency, Severe Bone Resorption, Spine fracture

Associated Therapies: Calcium supplementation, Nutritional supplementation, Vitamin D Supplementation, Vitamin supplementation

Clinical Trials

Vitamin D, Blood Pressure, Lipids, Infection and Depression

Phase 3

Completed

Conditions: Hypovitaminosis D

Interventions: Drug: Cholecalciferol
Drug: placebo

First Posted Date: 2009-08-17

Last Posted Date: 2012-09-05

Lead Sponsor: University of Tromso

Target Recruit Count: 250

Registration Number: NCT00960232

Locations: 🇳🇴
University of Tromsø, Tromsø, Norway

Vitamin D Supplementation in Veterans With Early-Stage Prostate Cancer

Phase 2

Completed

Conditions: Prostate Cancer

Interventions: Drug: Placebo daily for one year
Drug: vitamin D3

First Posted Date: 2009-08-06

Last Posted Date: 2017-10-09

Lead Sponsor: VA Office of Research and Development

Target Recruit Count: 83

Registration Number: NCT00953225

Locations: 🇺🇸
Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina, United States
🇺🇸
Medical University of South Carolina, Charleston, South Carolina, United States

Effect of Vitamin D3 on Vascular Function

Not Applicable

Completed

Conditions: Vitamin D Deficiency

Interventions: Drug: Placebo
Drug: Vitamin D

First Posted Date: 2009-07-29

Last Posted Date: 2018-07-17

Lead Sponsor: Charles Drew University of Medicine and Science

Target Recruit Count: 130

Registration Number: NCT00948298

Vitamin D and Arteriovenous Fistulae

Not Applicable

Completed

Conditions: End-stage Renal Disease

Interventions: Drug: Placebo
Drug: Vitamin D3

First Posted Date: 2009-06-03

Last Posted Date: 2014-07-02

Lead Sponsor: Emory University

Target Recruit Count: 52

Registration Number: NCT00912782

Locations: 🇺🇸
Emory University, Atlanta, Georgia, United States

Ph I/II of Vitamin D on Bone Mineral Density & Markers of Bone Resorption

Phase 1

Terminated

Conditions: Breast Cancer
Bone Diseases

Interventions: Drug: Vitamin D

First Posted Date: 2009-05-19

Last Posted Date: 2017-02-14

Lead Sponsor: Mark Pegram

Target Recruit Count: 8

Registration Number: NCT00904423

Locations: 🇺🇸
Stanford University School of Medicine, Stanford, California, United States

Impact of Vitamin D Supplementation on Lactation Associated Bone Loss

Not Applicable

Completed

Conditions: Osteoporosis

Interventions: Dietary Supplement: Multivitamin
Drug: Vitamin D3

First Posted Date: 2009-05-18

Last Posted Date: 2014-08-18

Lead Sponsor: Leigh Eck, MD

Target Recruit Count: 22

Registration Number: NCT00903344

Locations: 🇺🇸
University of Kansas Medical Center, Kansas City, Missouri, United States

Vitamin D in Minorities With Prediabetes

Not Applicable

Completed

Conditions: Pre-diabetes

Interventions: Drug: placebo
Drug: vitamin D

First Posted Date: 2009-04-07

Last Posted Date: 2013-06-14

Lead Sponsor: Charles Drew University of Medicine and Science

Target Recruit Count: 117

Registration Number: NCT00876928

Locations: 🇺🇸
Charles Drew University, Los Angeles, California, United States

Vitamin D in Postmenopausal Women at High Risk for Breast Cancer

Phase 2

Completed

Conditions: Breast Cancer

Interventions: Drug: Cholecalciferol
Drug: Placebo capsule

First Posted Date: 2009-03-11

Last Posted Date: 2017-09-27

Lead Sponsor: Columbia University

Target Recruit Count: 20

Registration Number: NCT00859651

Locations: 🇺🇸
Columbia University, New York, New York, United States

Metabolic Effects of Vitamin D in Patients With Type 2 Diabetes

Phase 2

Completed

Conditions: Type 2 Diabetes
Vitamin D Insufficiency

Interventions: Drug: Cholecalciferol

First Posted Date: 2008-12-22

Last Posted Date: 2010-07-12

Lead Sponsor: University of Aarhus

Target Recruit Count: 16

Registration Number: NCT00812578

Locations: 🇩🇰
Medical Research Unit, Medical Department M, Aarhus University Hospital, Aarhus, Denmark

Vitamin D AND Glucose Handling Evaluated by Glucose Clamp

Phase 2

Completed

Conditions: Insulin Sensitivity
Intraocular Pressure

First Posted Date: 2008-12-17

Last Posted Date: 2011-11-03

Lead Sponsor: University Hospital of North Norway

Target Recruit Count: 160

Registration Number: NCT00809744

Locations: 🇳🇴
University Hospital of North Norway, Tromsø, Norway

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2024. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy