Vitamin D3

Generic Name: Vitamin D3

Brand Names: Adrovance, Animi-3 With Vitamin D, Citranatal B-calm Kit, Citranatal Harmony, Fosamax Plus D, Fosavance, Infuvite, Infuvite Pediatric, Mvc-fluoride, Natafort, Pregvit, Vidextra

Drug Type: Small Molecule

Chemical Formula: C_₂₇H_₄₄O

CAS Number: 67-97-0

Unique Ingredient Identifier: 1C6V77QF41

Background: Vitamin D, in general, is a secosteroid generated in the skin when 7-dehydrocholesterol located there interacts with ultraviolet irradiation - like that commonly found in sunlight . Both the endogenous form of vitamin D (that results from 7-dehydrocholesterol transformation), vitamin D3 (cholecalciferol), and the plant-derived form, vitamin D2 (ergocalcifero...

Indication: Cholecalciferol use is indicated for the treatment of specific medical conditions like refractory rickets (or vitamin D resistant rickets), hypoparathyroidism, and familial hypophosphatemia .
...

Associated Conditions: Bone Fractures, Calcium and Vitamin D Deficiencies, Deficiency of Vitamin D3, Deficiency, Vitamin A, Deficiency, Vitamin D, Hip Fracture, Hypoparathyroidism, Hypophosphatemia, Familial, Menopause, Osteomalacia, Osteoporosis, Postmenopausal Osteoporosis, Vertebral Fractures, Vitamin D Resistant Rickets, Vitamin Deficiency, Severe Bone Resorption, Spine fracture

Associated Therapies: Calcium supplementation, Nutritional supplementation, Vitamin D Supplementation, Vitamin supplementation

Clinical Trials

Vitamin D3 in Systemic Lupus Erythematosus

Phase 2

Completed

Conditions: SLE
Lupus
Systemic Lupus Erythematosus

Interventions: Drug: Vitamin D3 placebo
Drug: Vitamin D3

First Posted Date: 2008-07-03

Last Posted Date: 2017-04-26

Lead Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)

Target Recruit Count: 57

Registration Number: NCT00710021

Locations: 🇺🇸
University of Rochester, Rochester, New York, United States
🇺🇸
University of Alabama, Birmingham, Alabama, United States
🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States

and more 5 locations

Vitamin D for the Prevention of Diabetes Type 2

Phase 2

Completed

Conditions: Impaired Glucose Tolerance

Interventions: Drug: cholecalciferol
Drug: Placebo

First Posted Date: 2008-05-28

Last Posted Date: 2015-09-22

Lead Sponsor: University of Tromso

Target Recruit Count: 511

Registration Number: NCT00685594

Locations: 🇳🇴
University of Tromso, Tromso, Norway

Cholecalciferol Supplementation, Muscle Strength

Phase 1

Completed

Conditions: Vitamin D Deficiency

Interventions: Drug: Lactose placebo
Drug: Cholecalciferol

First Posted Date: 2008-05-22

Last Posted Date: 2011-06-15

Lead Sponsor: Indian Council of Medical Research

Target Recruit Count: 40

Registration Number: NCT00682214

Role of Extrarenal 1-Alpha-Hydroxylase in Patients With End Stage Renal Disease

Not Applicable

Completed

Conditions: End-Stage Renal Disease

Interventions: Drug: Cholecalciferol

First Posted Date: 2008-05-14

Last Posted Date: 2014-04-29

Lead Sponsor: University of Kansas

Target Recruit Count: 7

Registration Number: NCT00677534

L-arginine and Vitamin D Adjunctive Therapy in Pulmonary Tuberculosis (TB)

Phase 3

Completed

Conditions: Smear Positive Pulmonary Tuberculosis

Interventions: Drug: L-arginine
Drug: Vitamin D
Drug: Placebo L-arginine
Drug: Placebo Vitamin D

First Posted Date: 2008-05-14

Last Posted Date: 2012-01-18

Lead Sponsor: Menzies School of Health Research

Target Recruit Count: 200

Registration Number: NCT00677339

Locations: 🇮🇩
Timika Tuberculosis Clinic and Community Hospital, Timika, Papua Province, Indonesia

Effect of Vitamin D Treatment in Primary Hyperparathyroidism

Phase 2

Completed

Conditions: Vitamin D Deficiency
Primary Hyperparathyroidism
Hypercalcemia

Interventions: Drug: Cholecalciferol

First Posted Date: 2008-05-07

Last Posted Date: 2013-11-18

Lead Sponsor: University of Aarhus

Target Recruit Count: 46

Registration Number: NCT00674154

Locations: 🇩🇰
Osteoporoseklinikken, Aarhus University Hospital, THG, Aarhus C, Denmark

Development of Vitamin D as a Therapy for Breast Cancer - Phase 2

Phase 2

Completed

Conditions: Breast Cancer

Interventions: Drug: Vitamin D

First Posted Date: 2008-04-10

Last Posted Date: 2017-12-02

Lead Sponsor: Stanford University

Target Recruit Count: 63

Registration Number: NCT00656019

Locations: 🇺🇸
Stanford University School of Medicine, Stanford, California, United States

High-Dose Vitamin D Deficiency in Burn Injury

Phase 3

Withdrawn

Conditions: Burn

Interventions: Drug: Vitamin D

First Posted Date: 2008-01-11

Last Posted Date: 2012-11-15

Lead Sponsor: The University of Texas Medical Branch, Galveston

Registration Number: NCT00591604

Vitamin D for Chemoprevention

Phase 1

Completed

Conditions: Hypertension
Prostate Cancer
Gastrointestinal Cancers

Interventions: Drug: Vitamin D
Dietary Supplement: Placebo

First Posted Date: 2008-01-03

Last Posted Date: 2015-04-01

Lead Sponsor: Dana-Farber Cancer Institute

Target Recruit Count: 328

Registration Number: NCT00585637

Locations: 🇺🇸
Dana-Farber Cancer Institute, Boston, Massachusetts, United States

Does Treatment of Hypovitaminosis D Increase Calcium Absorption?

Phase 4

Completed

Conditions: Hypoparathyroidism
Osteoporosis
Osteopenia
Vitamin D Deficiency
Hypercalcemia
Hypercalciuria

Interventions: Drug: Vitamin D

First Posted Date: 2007-12-28

Last Posted Date: 2023-07-24

Lead Sponsor: University of Wisconsin, Madison

Target Recruit Count: 19

Registration Number: NCT00581828

Locations: 🇺🇸
University of Wisconsin Hospital and Clinics, Madison, Wisconsin, United States

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2024. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy