Somatotropin

Generic Name
Somatotropin
Brand Names
Genotropin, Humatrope, Norditropin, Norditropin Nordiflex, Nutropin, Nutropinaq, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, NutropinAq
Drug Type
Biotech
Chemical Formula
-
CAS Number
12629-01-5
Unique Ingredient Identifier
NQX9KB6PCL
Background

Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and li...

Indication

Somatotropin is indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, short stature associated with Turner syndrome, Prader-Willi syndrome (PWS), idiopathic short stature (ISS), short stature or growth failure in short stature homeobox-containing gene (SHOX) deficiency, and shor...

Associated Conditions
Adult Onset Growth Hormone Deficiency, Cachexia, Childhood-onset Growth Hormone Deficiency, Growth Failure, HIV Wasting Syndrome, Short Bowel Syndrome (SBS), Short Stature
Associated Therapies
-
Clinical Trials
Related News

Effect of Growth Hormone on Bone Metabolism in Anorexia Nervosa

First Posted Date
2006-01-30
Last Posted Date
2020-09-02
Lead Sponsor
Massachusetts General Hospital
Target Recruit Count
21
Registration Number
NCT00283595
Locations
🇺🇸

Massachusettes General Hospital, Boston, Massachusetts, United States

Effect of Growth Hormone in Children With Growth Hormone Deficiency

First Posted Date
2005-12-06
Last Posted Date
2017-01-18
Lead Sponsor
Novo Nordisk A/S
Target Recruit Count
173
Registration Number
NCT00262249
Locations
🇺🇸

Novo Nordisk Investigational Site, Milwaukee, Wisconsin, United States

Predictive Markers in Growth Hormone Deficiency (GHD) and Turner Syndrome (TS) Children Treated With SAIZEN®

Phase 4
Completed
Conditions
Growth Hormone Deficiency
Turner Syndrome
Interventions
Drug: Saizen
First Posted Date
2005-11-21
Last Posted Date
2018-06-26
Lead Sponsor
Merck KGaA, Darmstadt, Germany
Target Recruit Count
318
Registration Number
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Locations
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Local Medical Information Office, Feltham, United Kingdom

🇫🇷

Local Medical InformationOffice, Paris, France

Controlled Study to Evaluate the Efficacy and Safety of the Treatment With Growth Hormone in Tibia Fractures

Phase 2
Completed
Conditions
Tibia Fractures
Bone Fracture
First Posted Date
2005-11-16
Last Posted Date
2017-01-23
Lead Sponsor
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Target Recruit Count
407
Registration Number
NCT00254514
Locations
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Novo Nordisk Investigational Site, Valencia, Spain

An Open-Label, Multi-centre, Phase III Study of Local Tolerability of ZOMACTON 10MG

Phase 3
Completed
Conditions
Turner's Syndrome
First Posted Date
2005-11-08
Last Posted Date
2011-05-20
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
27
Registration Number
NCT00250250
Locations
🇨🇿

Faculty Hospital Olomouc, Children's Clinic, Endocrinology Outpatient Department, I.P.Pavlova str. 6,, Olomouc, Czech Republic

🇫🇷

Service de Pédiatrie, Groupe Hospitalier du Havre, 55 bis, rue Gustave Flaubert, Le Havre cedex, France

🇫🇷

Centre d'Endocrinologie Pediatrique, 25 rue Boudet, Bordeaux, France

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Study to Define Optimal IGF-1 Monitoring in Children Treated With NutropinAq

First Posted Date
2005-10-07
Last Posted Date
2019-12-09
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Target Recruit Count
251
Registration Number
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Dienst Kindergeneeskunde, Edegem, Belgium

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University Hospital Wales, Cardiff, Wales, United Kingdom

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Centre Hospitalier General, Le Havre, France

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Growth Hormone and GnRH Agonist in Adolescents With Acquired Hypothyroidism

First Posted Date
2005-09-21
Last Posted Date
2020-10-30
Lead Sponsor
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Target Recruit Count
16
Registration Number
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Locations
🇺🇸

Baylor college of Medicine, Houston, Texas, United States

Efficacy and Safety of a High Dosage Compared to the Label Dosage of Somatropin in Early Pubertal Stage Children With Growth Hormone Deficiency

Phase 3
Completed
Conditions
Growth Hormone Deficiency
Interventions
Drug: Somatropin
First Posted Date
2005-09-19
Last Posted Date
2009-06-10
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
27
Registration Number
NCT00191165
Locations
🇮🇹

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Monday-Friday from 9:00 AM to 5:00 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician, Verona, Italy

Growth Hormone Treatment in Short Children Born Small for Gestational Age

Phase 3
Completed
Conditions
Infant, Small for Gestational Age
First Posted Date
2005-09-19
Last Posted Date
2007-06-15
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
200
Registration Number
NCT00191529
Locations
🇩🇪

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon-Fri from 9AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Koln, Germany

Effect of Cytokines on Growth of Children With Chronic Kidney Failure

Phase 4
Suspended
Conditions
Chronic Renal Insufficiency
First Posted Date
2005-09-19
Last Posted Date
2017-11-21
Lead Sponsor
Weill Medical College of Cornell University
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50
Registration Number
NCT00194883
Locations
🇺🇸

Weill Medical College of Cornell University, New York, New York, United States

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