Somatotropin
- Generic Name
- Somatotropin
- Brand Names
- Genotropin, Humatrope, Norditropin, Norditropin Nordiflex, Nutropin, Nutropinaq, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, NutropinAq
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 12629-01-5
- Unique Ingredient Identifier
- NQX9KB6PCL
- Background
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and li...
- Indication
Somatotropin is indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, short stature associated with Turner syndrome, Prader-Willi syndrome (PWS), idiopathic short stature (ISS), short stature or growth failure in short stature homeobox-containing gene (SHOX) deficiency, and shor...
- Associated Conditions
- Adult Onset Growth Hormone Deficiency, Cachexia, Childhood-onset Growth Hormone Deficiency, Growth Failure, HIV Wasting Syndrome, Short Bowel Syndrome (SBS), Short Stature
- Associated Therapies
- -
A Trial Investigating Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of a Single Dose of Long-acting Growth Hormone (Somapacitan) Compared to Daily Dosing of Norditropin® SimpleXx® in Children With Growth Hormone Deficiency
- Conditions
- Interventions
- First Posted Date
- 2013-10-31
- Last Posted Date
- 2020-12-24
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 32
- Registration Number
- NCT01973244
- Locations
- 🇨🇭
Novo Nordisk Investigational Site, Genève, Switzerland
The Role of Igf-1 Generation Test in Diagnosis and Treatment of Short Stature
- First Posted Date
- 2013-10-28
- Last Posted Date
- 2018-08-17
- Lead Sponsor
- Maimonides Medical Center
- Registration Number
- NCT01970800
- Locations
- 🇺🇸
Maimonides Medical Center, Brooklyn, New York, United States
Safety, PK/PD (Pharmacokinetics/Pharmacodynamics) and Efficacy of ACP-001 Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD)
- Conditions
- Interventions
- First Posted Date
- 2013-09-23
- Last Posted Date
- 2017-01-19
- Lead Sponsor
- Ascendis Pharma A/S
- Target Recruit Count
- 53
- Registration Number
- NCT01947907
- Locations
- 🇺🇦
Kharkiv National Medical University, Kharkiv, Ukraine
🇺🇦Institute of Endocrinology and Metabolism, Kiev, Ukraine
🇺🇦Donetsk Regional Children Clinical Hospital, Donetsk, Ukraine
Investigating the Long-term Efficacy and Safety of Two Doses of NN-220 (Somatropin) in Short Stature Due to Noonan Syndrome
- First Posted Date
- 2013-08-23
- Last Posted Date
- 2020-08-10
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 51
- Registration Number
- NCT01927861
- Locations
- 🇯🇵
Novo Nordisk Investigational Site, Zentsuji, Kagawa, Japan
Assessment Of Gh-Igf-1 Axis In Children With Chronic Myelogenous Leukemia (CML) In Remission
- First Posted Date
- 2013-07-17
- Last Posted Date
- 2013-07-17
- Target Recruit Count
- 20
- Registration Number
- NCT01901666
- Locations
- 🇮🇳
Postgraduate Institute of Medical Education and Research, Chandigarh, UT, India
Special Investigation Of Genotropin Long Follow-Up For Patients With A Small For Gestational Age "Scoped for Japanese"
- First Posted Date
- 2013-07-12
- Last Posted Date
- 2023-09-25
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 482
- Registration Number
- NCT01897766
Retrospective Study Of The Influence Of Age At Start Of Growth Hormone Treatment On Height Gain In Children Born Small for Gestational Age
- First Posted Date
- 2013-07-12
- Last Posted Date
- 2014-01-20
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 264
- Registration Number
- NCT01897753
- Locations
- 🇪🇸
Hospital Virgen de la Arrixaca, El Palmar, Murcia, Spain
🇪🇸H.Marqués de Valdecilla, Santander, Cantabria, Spain
🇪🇸H. Germans Trias i Pujol, Badalona, Barcelona, Spain
Effects of Growth Hormone Administration on Muscle Strength and Body Composition in Men Over 50 Years Old
- First Posted Date
- 2013-05-15
- Last Posted Date
- 2014-09-03
- Lead Sponsor
- Universidade Federal do Rio de Janeiro
- Target Recruit Count
- 13
- Registration Number
- NCT01853566
- Locations
- 🇧🇷
Hospital Universitário Clementino Fraga Filho - UFRJ, Rio de Janeiro, Brazil
Safety, Tolerability and Efficacy of Weekly TV-1106 in Adults With Growth Hormone Deficiency
- Conditions
- Interventions
- First Posted Date
- 2013-03-14
- Last Posted Date
- 2021-12-10
- Lead Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
- Target Recruit Count
- 52
- Registration Number
- NCT01811576
- Locations
- 🇬🇷
Teva Investigational Site 63044, Athens, Greece
🇸🇰Teva Investigational Site 62022, Bratislava, Slovakia
🇸🇮Teva Investigational Site 64016, Ljubljana, Slovenia
Efficacy and Safety of Recombinant Human Growth Hormone on Height Velocity in Subjects With Idiopathic Short Stature
- First Posted Date
- 2013-01-29
- Last Posted Date
- 2017-06-02
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 54
- Registration Number
- NCT01778023
- Locations
- 🇰🇷
Novo Nordisk Investigational Site, Suwon, Korea, Republic of
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