Somatotropin
- Generic Name
- Somatotropin
- Brand Names
- Genotropin, Humatrope, Norditropin, Norditropin Nordiflex, Nutropin, Nutropinaq, Omnitrope, Saizen, Serostim, Zomacton, Zorbtive, NutropinAq
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 12629-01-5
- Unique Ingredient Identifier
- NQX9KB6PCL
- Background
Human growth hormone (HGH), also known as somatotropin, is a peptide hormone that is synthesized and secreted by the somatotropic cells of the anterior pituitary gland. Growth hormone plays an essential role in growth regulation during childhood as well as other basal metabolic functions, muscle and fat mass regulation, blood glucose level regulation, and li...
- Indication
Somatotropin is indicated for the treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone, short stature associated with Turner syndrome, Prader-Willi syndrome (PWS), idiopathic short stature (ISS), short stature or growth failure in short stature homeobox-containing gene (SHOX) deficiency, and shor...
- Associated Conditions
- Adult Onset Growth Hormone Deficiency, Cachexia, Childhood-onset Growth Hormone Deficiency, Growth Failure, HIV Wasting Syndrome, Short Bowel Syndrome (SBS), Short Stature
- Associated Therapies
- -
Combined Dehydropeiandrosterone and Growth Hormone in Women With Expected Poor Ovarian Response Undergoing ICSI
- Conditions
- Interventions
- First Posted Date
- 2016-05-10
- Last Posted Date
- 2018-01-03
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 230
- Registration Number
- NCT02766764
- Locations
- 🇪🇬
Cairo university hospitals, Cairo, Egypt
🇪🇬Dar AlTeb subfertility centre, Cairo, Egypt
Augmenting Growth Hormone to Ameliorate Nonalcoholic Fatty Liver Disease in Adolescents
- First Posted Date
- 2016-04-01
- Last Posted Date
- 2022-09-07
- Lead Sponsor
- Massachusetts General Hospital
- Target Recruit Count
- 24
- Registration Number
- NCT02726542
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Evaluation of Efficacy and Safety of Recombinant Somatroipn in Patients With Growth Hormone Deficiency
- First Posted Date
- 2016-02-26
- Last Posted Date
- 2016-02-29
- Lead Sponsor
- Daewoong Pharmaceutical Co. LTD.
- Target Recruit Count
- 52
- Registration Number
- NCT02693522
- Locations
- 🇰🇷
Kyunghee University Hospital, Seoul, Korea, Republic of
Substrate Metabolism, Growth Hormone Signaling (GH), and Insulin Sensitivity During GH and Ketone Bodies Infusion
- First Posted Date
- 2016-01-14
- Last Posted Date
- 2017-11-01
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 10
- Registration Number
- NCT02655263
- Locations
- 🇩🇰
Aarhus University Hospital, Aarhus, Denmark
A Study to Evaluate the Efficacy of Somatropin in the Treatment of Patellar Tendinopathy
- Conditions
- Interventions
- First Posted Date
- 2015-11-05
- Last Posted Date
- 2022-03-31
- Lead Sponsor
- Hospital for Special Surgery, New York
- Registration Number
- NCT02597660
- Locations
- 🇺🇸
Hospital for Special Surgery, New York, New York, United States
Granulocyte Colony Stimulating Factor And Growth Hormone In Cirrhosis Of Liver: An Open Label Study
- Conditions
- Interventions
- First Posted Date
- 2015-05-21
- Last Posted Date
- 2017-08-29
- Target Recruit Count
- 65
- Registration Number
- NCT02451033
- Locations
- 🇮🇳
Dept. of Hepatology, PGIMER, Chandigarh, Chandigarh, India
🇮🇳Department of Hepatology,Postgraduate Institute of Medical Education and Research, Chandigarh, India
Evaluation of rGH Therapy to Prevent Muscle Atrophy in Patients With ACL Tears
- Conditions
- Interventions
- First Posted Date
- 2015-04-17
- Last Posted Date
- 2020-01-06
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 20
- Registration Number
- NCT02420353
- Locations
- 🇺🇸
University of Michigan, Ann Arbor, Michigan, United States
A Trial to Compare the Safety of Once Weekly Dosing of Somapacitan With Daily Norditropin® FlexPro® for 26 Weeks in Previously Human Growth Hormone Treated Adults With Growth Hormone Deficiency
- Conditions
- Interventions
- First Posted Date
- 2015-03-09
- Last Posted Date
- 2020-07-09
- Lead Sponsor
- Novo Nordisk A/S
- Target Recruit Count
- 92
- Registration Number
- NCT02382939
- Locations
- 🇬🇧
Novo Nordisk Investigational Site, Manchester, United Kingdom
Low-dose GH Supplementation Increases Clinical Pregnancy Rate
- First Posted Date
- 2015-02-10
- Last Posted Date
- 2017-05-10
- Lead Sponsor
- Centro de Infertilidad y Reproducción Humana
- Target Recruit Count
- 64
- Registration Number
- NCT02359695
- Locations
- 🇪🇸
Centro de Infertilidad y Reproducción Humana (CIRH), Barcelona, Spain
Long-Acting Growth Hormone in Children Compared to Daily rhGH
- First Posted Date
- 2015-01-15
- Last Posted Date
- 2022-12-30
- Lead Sponsor
- Versartis Inc.
- Target Recruit Count
- 138
- Registration Number
- NCT02339090
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