Regadenoson
- Generic Name
- Regadenoson
- Brand Names
- Lexiscan, Rapiscan
- Drug Type
- Small Molecule
- Chemical Formula
- C15H18N8O5
- CAS Number
- 313348-27-5
- Unique Ingredient Identifier
- 7AXV542LZ4
- Background
Regadenoson is an A2A adenosine receptor agonist that causes coronary vasodilation and used for myocardial perfusion imagining. Manufactured by Astellas and FDA approved April 10, 2008.
- Indication
Diagnostic agent for radionuclide myocardial perfusion imaging (MPI)
A Phase II Trial of Regadenoson in Sickle Cell Anemia
- First Posted Date
- 2013-02-11
- Last Posted Date
- 2018-02-07
- Lead Sponsor
- Dana-Farber Cancer Institute
- Target Recruit Count
- 100
- Registration Number
- NCT01788631
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
🇺🇸Baylor College of Medicine, Houston, Texas, United States
🇺🇸Duke University, Durham, North Carolina, United States
Development of a PET-MR Myocardial Perfusion Examination Using Regadenoson
- First Posted Date
- 2013-01-30
- Last Posted Date
- 2018-06-15
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 16
- Registration Number
- NCT01779869
- Locations
- 🇺🇸
Center for Clinical Imaging Research at Washington University School of Medicine, Saint Louis, Missouri, United States
Regadenoson Stress-MRI to Identify Coronary Artery Disease in Atrial Fibrillation Patients
- Conditions
- Atrial FibrillationCoronary Artery Disease
- Interventions
- First Posted Date
- 2012-10-19
- Last Posted Date
- 2017-12-13
- Lead Sponsor
- University of Utah
- Target Recruit Count
- 30
- Registration Number
- NCT01710254
- Locations
- 🇺🇸
University of Utah, Salt Lake City, Utah, United States
Absolute Quantification of Coronary Flow Reserve by Stress Perfusion MRI
- Conditions
- Myocardial Ischemia
- Interventions
- Drug: gadofoveset trisodium
- First Posted Date
- 2012-08-01
- Last Posted Date
- 2019-08-28
- Lead Sponsor
- Northwestern University
- Target Recruit Count
- 20
- Registration Number
- NCT01655043
- Locations
- 🇺🇸
Northwestern University, Chicago, Illinois, United States
A Study to Assess Regadenoson Administration Following an Inadequate Exercise Stress Test as Compared to Regadenoson Alone for Myocardial Perfusion Imaging (MPI) Using Single Photon Emission Computed Tomography (SPECT)
- Conditions
- Coronary Artery Disease (CAD)
- Interventions
- Procedure: Single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI)
- First Posted Date
- 2012-06-13
- Last Posted Date
- 2016-02-08
- Lead Sponsor
- Astellas Pharma Global Development, Inc.
- Target Recruit Count
- 1147
- Registration Number
- NCT01618669
- Locations
- 🇺🇸
Rush University Medical Center, Chicago, Illinois, United States
🇺🇸Mobile Heart Specialists, PC, Mobile, Alabama, United States
🇺🇸HOCC - New Britain Campus, New Britain, Connecticut, United States
Microvascular Blood Flow in Sickle Cell Anemia
- Conditions
- Sickle Cell DiseaseSickle Cell Anemia
- Interventions
- Procedure: contrast-enhanced ultrasound
- First Posted Date
- 2012-03-29
- Last Posted Date
- 2024-06-26
- Lead Sponsor
- Versiti
- Target Recruit Count
- 91
- Registration Number
- NCT01566890
- Locations
- 🇺🇸
The University of Illinois, Chicago, Illinois, United States
🇺🇸Medical College of Wisconsin, Milwaukee, Wisconsin, United States
Diagnostic Study of Rapid Regadenoson Stress Cardiovascular Magnetic Resonance (CMR) to Detect Coronary Artery Disease
- First Posted Date
- 2011-10-04
- Last Posted Date
- 2017-10-03
- Lead Sponsor
- Dipan Shah
- Target Recruit Count
- 50
- Registration Number
- NCT01446094
- Locations
- 🇺🇸
The Methodist Hospital, Houston, Texas, United States
Distribution of Rubidium-82, Nitrogen-13 Ammonia, and Fluorine-18 Fluorodeoxyglucose in Normal Volunteers
- Conditions
- Heart Disease
- Interventions
- First Posted Date
- 2011-09-14
- Last Posted Date
- 2019-01-30
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 70
- Registration Number
- NCT01433705
- Locations
- 🇺🇸
University of Michigan Hospital, Ann Arbor, Michigan, United States
Myocardial Blood Flow by PET and N-13 Ammonia During Regadenoson vs Adenosine Stress
- Conditions
- Coronary Artery Disease
- Interventions
- First Posted Date
- 2011-06-09
- Last Posted Date
- 2013-09-05
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 12
- Registration Number
- NCT01370265
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
A Study of Regadenoson in Subjects Undergoing Stress Myocardial Perfusion Imaging (MPI) Using Multidetector Computed Tomography (MDCT) Compared to Single Photon Emission Computed Tomography (SPECT)
- Conditions
- Coronary Artery Disease (CAD)
- Interventions
- Radiation: technetium Tc99m sestamibi /technetium Tc99m tetrafosminRadiation: ContrastProcedure: Single Photon Emission Computed TomographyProcedure: Multidetector Computed Tomography
- First Posted Date
- 2011-04-13
- Last Posted Date
- 2024-12-04
- Lead Sponsor
- Astellas Pharma Inc
- Target Recruit Count
- 124
- Registration Number
- NCT01334918
- Locations
- 🇺🇸
Cardiovascular Research Center of South Florida, Miami, Florida, United States
🇺🇸Baptist Hospital of Miami, Miami, Florida, United States
🇺🇸Harbor UCLA Medical Center, Torrance, California, United States
Drug Development Updates
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