Metoprolol
- Generic Name
- Metoprolol
- Brand Names
- Kapspargo, Lopressor, Lopressor Hct, Toprol
- Drug Type
- Small Molecule
- Chemical Formula
- C15H25NO3
- CAS Number
- 51384-51-1
- Unique Ingredient Identifier
- GEB06NHM23
- Background
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date, it is one of the preferre...
- Indication
Metoprolol is indicated for the treatment of angina, heart failure, myocardial infarction, atrial fibrillation, atrial flutter and hypertension.
Some off-label uses of metoprolol include supraventricular tachycardia and thyroid storm.
...
- Associated Conditions
- Angina Pectoris, Atrial Fibrillation, Hypertension, Migraine, Myocardial Infarction, Supraventricular Tachycardia (SVT), Thyroid Crisis, Chronic heart failure with reduced ejection fraction (NYHA Class II), Chronic heart failure with reduced ejection fraction (NYHA Class III)
- Associated Therapies
- -
Effects of Beta-blockade on Platelet Aggregation in Acute Coronary Syndrome
- First Posted Date
- 2016-06-22
- Last Posted Date
- 2022-03-31
- Lead Sponsor
- Federico II University
- Target Recruit Count
- 100
- Registration Number
- NCT02809820
- Locations
- 🇮🇹
Federico II University of Naples, Naples, Italy
Radiofrequency Ablation of Symptomatic Frequent Ventricular Premature Complexes in Pediatric Population
- First Posted Date
- 2016-05-13
- Last Posted Date
- 2016-09-09
- Target Recruit Count
- 124
- Registration Number
- NCT02772354
- Locations
- 🇷🇺
State Research Institute of CIrculation Pathology Novosibirsk, Russian Federation, Novosibirsk, Russian Federation
🇷🇺Research Clinical Institute of Pediatrics, N.I. Pirogov Russian National Research Medical University, Moscow, Russian Federation
This Study Tests the Effect of Risankizumab on the Metabolism in the Liver of Five Additional Drugs to Study Possible Drug Interactions in Patients With Psoriasis With or Without Psoriatic Arthritis
- Conditions
- Interventions
- First Posted Date
- 2016-05-13
- Last Posted Date
- 2017-09-25
- Lead Sponsor
- AbbVie
- Target Recruit Count
- 21
- Registration Number
- NCT02772601
- Locations
- 🇩🇪
Boehringer Ingelheim Investigational Site, Berlin, Germany
Pilot - Peri-operative Beta Blockade
- Conditions
- Interventions
- First Posted Date
- 2016-04-21
- Last Posted Date
- 2020-01-30
- Lead Sponsor
- Washington University School of Medicine
- Target Recruit Count
- 70
- Registration Number
- NCT02746575
- Locations
- 🇺🇸
Barnes-Jewish Hospital/Washington University in St. Louis School of Medicine, Saint Louis, Missouri, United States
Rate Control in Atrial Fibrillation II
- Conditions
- Interventions
- First Posted Date
- 2016-03-02
- Last Posted Date
- 2022-01-05
- Lead Sponsor
- Asker & Baerum Hospital
- Target Recruit Count
- 122
- Registration Number
- NCT02695992
- Locations
- 🇳🇴
Vestre Viken Hospital Trust, Baerum Hospital, Rud, Akershus, Norway
Open Label, Drug-Drug Interaction (DDI) Study of Dupilumab (REGN668/SAR231893) in Patients With Moderate to Severe Atopic Dermatitis (AD)
- Conditions
- Interventions
- First Posted Date
- 2016-01-06
- Last Posted Date
- 2016-08-22
- Lead Sponsor
- Regeneron Pharmaceuticals
- Target Recruit Count
- 14
- Registration Number
- NCT02647086
- Locations
- 🇺🇸
Regeneron Study Site, Raleigh, North Carolina, United States
The Effects of Nifedipine and Metoprolol on Blood Pressure Variability in Northern Chinese
- First Posted Date
- 2015-08-03
- Last Posted Date
- 2015-09-30
- Target Recruit Count
- 40
- Registration Number
- NCT02513927
- Locations
- 🇭🇺
Twenty-four-hour ambulatory BP monitoring, Budapest, Hungary
Comparison of Metoprolol and Tramadol With Remifentanil in Endoscopic Sinus Surgery
- First Posted Date
- 2015-06-30
- Last Posted Date
- 2023-12-20
- Lead Sponsor
- Recep Tayyip Erdogan University
- Target Recruit Count
- 88
- Registration Number
- NCT02484859
- Locations
- 🇹🇷
Recep Tayyip Erdogan University, Rize, Eastern Blacksea, Turkey
Effects of Metoprolol and Amlodipine on Cardiac Remodeling, Arrhythmias and Blood Pressure Variation in Hypertensive Patients With Sleep Apnea Syndrome
- First Posted Date
- 2015-04-03
- Last Posted Date
- 2017-02-15
- Target Recruit Count
- 20
- Registration Number
- NCT02408172
- Locations
- 🇨🇳
Portable polysomnography, Suzhou, Jiangsu, China
🇭🇺Twenty-four-hour ambulatory BP monitoring, Budapest, Hungary
Dabigatran in an Interaction Probe Drug Cocktail
- Conditions
- Interventions
- First Posted Date
- 2015-02-12
- Last Posted Date
- 2018-08-14
- Lead Sponsor
- Turku University Hospital
- Target Recruit Count
- 16
- Registration Number
- NCT02361619
- Locations
- 🇫🇮
Teutori CPRU, Turku, Finland
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.