Metoprolol
- Generic Name
- Metoprolol
- Brand Names
- Kapspargo, Lopressor, Lopressor Hct, Toprol
- Drug Type
- Small Molecule
- Chemical Formula
- C15H25NO3
- CAS Number
- 51384-51-1
- Unique Ingredient Identifier
- GEB06NHM23
- Background
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date, it is one of the preferre...
- Indication
Metoprolol is indicated for the treatment of angina, heart failure, myocardial infarction, atrial fibrillation, atrial flutter and hypertension.
Some off-label uses of metoprolol include supraventricular tachycardia and thyroid storm.
...
- Associated Conditions
- Angina Pectoris, Atrial Fibrillation, Hypertension, Migraine, Myocardial Infarction, Supraventricular Tachycardia (SVT), Thyroid Crisis, Chronic heart failure with reduced ejection fraction (NYHA Class II), Chronic heart failure with reduced ejection fraction (NYHA Class III)
- Associated Therapies
- -
The Effect of Metoprolol on Anaesthesia, the Need for Analgesics, and Pain in Breast Cancer Patients
- First Posted Date
- 2014-10-21
- Last Posted Date
- 2018-03-22
- Lead Sponsor
- Kuopio University Hospital
- Registration Number
- NCT02269696
The Effect of BI 187004 on the Pharmacokinetics of Cytochrome P450 Substrates (Caffeine, Warfarin, Omeprazole, Metoprolol and Midazolam) and a P Glycoprotein Substrate (Digoxin)
- Conditions
- Interventions
- First Posted Date
- 2014-10-01
- Last Posted Date
- 2014-12-23
- Lead Sponsor
- Boehringer Ingelheim
- Target Recruit Count
- 24
- Registration Number
- NCT02254148
- Locations
- 🇩🇪
1307.19.1 Boehringer Ingelheim Investigational Site, Biberach, Germany
Rate Control in Atrial Fibrillation
- First Posted Date
- 2014-09-29
- Last Posted Date
- 2016-06-16
- Lead Sponsor
- Creighton University
- Target Recruit Count
- 20
- Registration Number
- NCT02251509
- Locations
- 🇺🇸
Creighton University, Omaha, Nebraska, United States
Acute Cardioversion Versus Wait And See-approach for Symptomatic Atrial Fibrillation in the Emergency Department
- First Posted Date
- 2014-09-25
- Last Posted Date
- 2020-01-21
- Lead Sponsor
- Maastricht University Medical Center
- Target Recruit Count
- 437
- Registration Number
- NCT02248753
- Locations
- 🇳🇱
VU University Medical Center, Amsterdam, Netherlands
🇳🇱Antonius Ziekenhuis, Sneek, Netherlands
🇳🇱University Medical Center Groningen, Groningen, Netherlands
Assessment of Metoprolol in the Prevention of Vasovagal Syncope in Aging Subjects
- Conditions
- Interventions
- First Posted Date
- 2014-04-25
- Last Posted Date
- 2024-05-09
- Lead Sponsor
- University of Calgary
- Target Recruit Count
- 52
- Registration Number
- NCT02123056
- Locations
- 🇨🇦
Hopital du Sacre-Coeur de Montreal, Montreal, Quebec, Canada
🇨🇦St. Boniface General, Winnipeg, Manitoba, Canada
Sarpogrelate Drug Interaction
- Conditions
- Interventions
- First Posted Date
- 2014-03-27
- Last Posted Date
- 2015-02-25
- Lead Sponsor
- Ajou University School of Medicine
- Target Recruit Count
- 9
- Registration Number
- NCT02097511
- Locations
- 🇰🇷
Ajou University School of Medicine, Suwon, Gyeonggi, Korea, Republic of
Randomized Trial Comparing Diltiazem and Metoprolol For Atrial Fibrillation Rate Control
- First Posted Date
- 2014-01-01
- Last Posted Date
- 2017-08-09
- Lead Sponsor
- CAMC Health System
- Target Recruit Count
- 150
- Registration Number
- NCT02025465
- Locations
- 🇺🇸
Charleston Area Medical Center, Charleston, West Virginia, United States
Supramaximal Titrated Inhibition of RAAS in Dilated Cardiomyopathy
- Conditions
- Interventions
- First Posted Date
- 2013-08-06
- Last Posted Date
- 2014-05-19
- Lead Sponsor
- Xijing Hospital
- Target Recruit Count
- 480
- Registration Number
- NCT01917149
- Locations
- 🇨🇳
Xijing Hospital, Department of Cardiology, Xi'an, China
Comparison of Diltiazem and Metoprolol in the Management of Acute Atrial Fibrillation or Atrial Flutter
- Conditions
- Interventions
- First Posted Date
- 2013-08-02
- Last Posted Date
- 2014-05-15
- Lead Sponsor
- Antonios Likourezos
- Target Recruit Count
- 54
- Registration Number
- NCT01914926
- Locations
- 🇺🇸
Maimonides Medical Center, Brooklyn, New York, United States
Renal Denervation in Patients After Acute Coronary Syndrome
- Conditions
- Interventions
- First Posted Date
- 2013-07-17
- Last Posted Date
- 2015-09-23
- Target Recruit Count
- 80
- Registration Number
- NCT01901549
- Locations
- 🇷🇺
State Research Institute of Circulation Pathology, Novosibirsk, Russian Federation
Drug Development Updates
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