Metoprolol
- Generic Name
- Metoprolol
- Brand Names
- Kapspargo, Lopressor, Lopressor Hct, Toprol
- Drug Type
- Small Molecule
- Chemical Formula
- C15H25NO3
- CAS Number
- 51384-51-1
- Unique Ingredient Identifier
- GEB06NHM23
- Background
Metoprolol is a selective beta-1 blocker commonly employed as the succinate and tartrate derivatives depending if the formulation is designed to be of immediate release or extended release. The possibility of the generation of these formulations comes from the lower systemic bioavailability of the succinate derivative. To this date, it is one of the preferre...
- Indication
Metoprolol is indicated for the treatment of angina, heart failure, myocardial infarction, atrial fibrillation, atrial flutter and hypertension.
Some off-label uses of metoprolol include supraventricular tachycardia and thyroid storm.
...
- Associated Conditions
- Angina Pectoris, Atrial Fibrillation, Hypertension, Migraine, Myocardial Infarction, Supraventricular Tachycardia (SVT), Thyroid Crisis, Chronic heart failure with reduced ejection fraction (NYHA Class II), Chronic heart failure with reduced ejection fraction (NYHA Class III)
- Associated Therapies
- -
Safety Study to Lower the Risk of Heart Failure is Also Effective in Reducing Stiffness of the Arteries
- First Posted Date
- 2009-01-27
- Last Posted Date
- 2016-02-05
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 70
- Registration Number
- NCT00829296
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
Effects of Heart Rate Reduction on Central Arterial Pressure in Healthy Individuals
- Conditions
- Interventions
- First Posted Date
- 2009-01-19
- Last Posted Date
- 2020-08-17
- Lead Sponsor
- Bayside Health
- Target Recruit Count
- 2
- Registration Number
- NCT00825123
- Locations
- 🇦🇺
The Alfred Hospital, Melbourne, Victoria, Australia
Prevention of Anthracycline or Trastuzumab Induced Cardiomyopathy by Metoprolol
- First Posted Date
- 2008-12-10
- Last Posted Date
- 2022-02-25
- Lead Sponsor
- University of Maryland, Baltimore
- Target Recruit Count
- 15
- Registration Number
- NCT00806390
- Locations
- 🇺🇸
University of Maryland, Baltimore, Maryland, United States
Comparative Effect of Nebivolol vs. Metoprolol on Insulin Sensitivity and Fibrinolytic Balance in Metabolic Syndrome
- Conditions
- Interventions
- First Posted Date
- 2008-10-20
- Last Posted Date
- 2012-10-23
- Lead Sponsor
- Vanderbilt University
- Target Recruit Count
- 46
- Registration Number
- NCT00775671
- Locations
- 🇺🇸
Vanderbilt University Medical Center, Nashville, Tennessee, United States
A Comparison of the Effects of Intraoperative Administration of Metoprolol or Esmolol on General Anesthetic Requirement
- Conditions
- Interventions
- First Posted Date
- 2008-09-22
- Last Posted Date
- 2017-07-31
- Lead Sponsor
- University of Oklahoma
- Target Recruit Count
- 60
- Registration Number
- NCT00756236
- Locations
- 🇺🇸
Univeristy of Oklahoma Health Sciences Center Dept. Anesthesiology, Oklahoma City, Oklahoma, United States
Pain Relief of Metoprolol Versus Metoprolol Plus Morphine in Acute Chest Pain
- Conditions
- Interventions
- First Posted Date
- 2008-07-18
- Last Posted Date
- 2008-07-18
- Lead Sponsor
- Sahlgrenska University Hospital, Sweden
- Registration Number
- NCT00718406
- Locations
- 🇸🇪
Medical Institution, Dept of Molecular and Clinical Medicine, Sahlgrenska University Hospital, Göteborg, Sweden
Black Education and Treatment of Hypertension (BEAT HTN)
- First Posted Date
- 2008-04-21
- Last Posted Date
- 2012-12-04
- Lead Sponsor
- Creighton University
- Target Recruit Count
- 99
- Registration Number
- NCT00661895
- Locations
- 🇺🇸
Creighton Community Health Center, Omaha, Nebraska, United States
Comparison of Blood Pressure Medications on Metabolism
- First Posted Date
- 2008-03-25
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- University of New Mexico
- Target Recruit Count
- 22
- Registration Number
- NCT00642434
- Locations
- 🇺🇸
UNMHSC, Albuquerque, New Mexico, United States
Clonidine to Prevent Implantable Cardiovertor Defibrillator Firing
- Conditions
- Interventions
- First Posted Date
- 2008-01-03
- Last Posted Date
- 2018-07-24
- Lead Sponsor
- James Martins
- Registration Number
- NCT00585871
- Locations
- 🇺🇸
UIHC, Iowa City, Iowa, United States
Beta-blocker Before Extubation
- First Posted Date
- 2007-11-26
- Last Posted Date
- 2017-02-28
- Lead Sponsor
- Gregory A. Schmidt
- Registration Number
- NCT00563238
- Locations
- 🇺🇸
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.