Cefuroxime

Generic Name: Cefuroxime

Brand Names: Ceftin

Drug Type: Small Molecule

Chemical Formula: C_₁₆H_₁₆N_₄O_₈S

CAS Number: 55268-75-2

Unique Ingredient Identifier: O1R9FJ93ED

Background: Broad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.

Indication: For the treatment of many different types of bacterial infections such as bronchitis, sinusitis, tonsillitis, ear infections, skin infections, gonorrhea, and urinary tract infections.

Associated Conditions: Acute Bacterial Exacerbation of Chronic Bronchitis (ABECB), Animal bite, Bacterial Infections, Bone and Joint Infections, Impetigo, Lower Respiratory Tract Infection (LRTI), Lyme Disease, Maxillary Sinusitis, Meningitis, Neisseria Gonorrhoeae Infection, Septicemia, Skin and Subcutaneous Tissue Bacterial Infections, Urinary Tract Infection, Bacterial otitis media, Mild Streptococcal pharyngitis, Mild Streptococcal tonsillitis, Moderate Streptococcal pharyngitis, Moderate Streptococcal tonsillitis

Associated Therapies: -

Clinical Trials

The Preventive Infection Role of One Week Antibiotics Before Minimally Invasive Upper Tract Lithotomy

Early Phase 1

Conditions: Complication of Surgical Procedure

Interventions: Drug: levofloxacin
Drug: Nitrofurantoin
Drug: cefuroxime

First Posted Date: 2016-06-03

Last Posted Date: 2019-10-01

Lead Sponsor: Xinhua Hospital, Shanghai Jiao Tong University School of Medicine

Target Recruit Count: 150

Registration Number: NCT02789579

Locations: 🇨🇳
Department of Pharmacy, Xinhua Hospital, Shanghai Jiaotong University School of Medicine.Kongjiang Road 1665,, Shanghai, Shanghai, China

Antibiotics and Gut Microbiota Among Newborn Infants

Phase 4

Completed

Conditions: Surgical Wound Infection
Infection; Cesarean Section
Complications; Cesarean Section

Interventions: Drug: Cefuroxime

First Posted Date: 2014-02-27

Last Posted Date: 2014-08-12

Lead Sponsor: Odense University Hospital

Target Recruit Count: 42

Registration Number: NCT02072798

Locations: 🇩🇰
Odense University Hospital, Odense, Fyn, Denmark

RCT of Postoperative Infections Following Caesarean Section Infections Following Caesarean Section

Phase 4

Withdrawn

Conditions: Postoperative Infection

Interventions: Drug: Cefuroxime

First Posted Date: 2013-12-11

Last Posted Date: 2015-04-21

Lead Sponsor: Odense University Hospital

Registration Number: NCT02009098

Locations: 🇩🇰
Hospital of South West Jutland, Esbjerg, Denmark
🇩🇰
Odense University Hospital, Odense, Denmark
🇩🇰
Hvidovre Hospital, Hvidovre, Denmark

Antibiotic Prophylaxis for Transrectal Prostate Biopsy

Phase 4

Completed

Conditions: Infection

Interventions: Drug: trimethoprim-sulfamethoxazole
Drug: Ciprofloxacin
Drug: cefuroxime
Drug: ceftriaxone
Drug: gentamicin
Drug: amikacin
Drug: aztreonam
Drug: imipenem

First Posted Date: 2012-08-08

Last Posted Date: 2019-06-25

Lead Sponsor: Northwestern University

Target Recruit Count: 563

Registration Number: NCT01659866

Locations: 🇺🇸
Northwestern University Department of Urology, Chicago, Illinois, United States

Comparison of Doxycycline and Cefuroxime Axetil for Treatment of Erythema Migrans: Clinical and Microbiological Outcome

Phase 4

Completed

Conditions: Erythema Migrans
Post-Lyme Disease Symptoms

Interventions: Drug: doxycycline
Drug: cefuroxime axetil

First Posted Date: 2012-01-25

Last Posted Date: 2012-01-25

Lead Sponsor: University Medical Centre Ljubljana

Target Recruit Count: 544

Registration Number: NCT01518192

Locations: 🇸🇮
Institute of Microbiology and Immunology, Medical Faculty, University of Ljubljana, Ljubljana, Slovenia
🇸🇮
Department of Infectious Diseases, University Medical Center Ljubljana, Ljubljana, Slovenia, Ljubljana, Slovenia