Midazolam
- Generic Name
- Midazolam
- Brand Names
- Buccolam, Busulfex, Nayzilam, Seizalam
- Drug Type
- Small Molecule
- Chemical Formula
- C18H13ClFN3
- CAS Number
- 59467-70-8
- Unique Ingredient Identifier
- R60L0SM5BC
- Background
Midazolam is a short-acting hypnotic-sedative drug with anxiolytic, muscle relaxant, anticonvulsant, sedative, hypnotic, and amnesic properties. It belongs to a class of drugs called benzodiazepines. This drug is unique from others in this class due to its rapid onset of effects and short duration of action. Midazolam is available by oral, rectal, intranasal...
- Indication
Midazolam has different indications depending on its formulation by the FDA.
Nasal
...
- Associated Conditions
- Epileptic seizure, Status Epilepticus
- Associated Therapies
- Anaesthesia, Anxiolytic therapy therapy, Sedation for mechanically-ventilated patients, Preoperative amnesia therapy, Preoperative sedation therapy
Trial Evaluating the Efficacy of Remimazolam in Endobronchial Ultrasound Guided Transbronchial Needle Aspiration
- First Posted Date
- 2024-02-23
- Last Posted Date
- 2024-02-23
- Lead Sponsor
- Yeungnam University Hospital
- Target Recruit Count
- 330
- Registration Number
- NCT06275594
- Locations
- 🇰🇷
Yeungnam University Hospital, Daegu, Namgu, Korea, Republic of
A Study to Learn If the Study Medicine Called Vepdegestrant Changes How the Body Processes the Other Study Medicine Called Midazolam
- First Posted Date
- 2024-02-13
- Last Posted Date
- 2024-05-23
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 15
- Registration Number
- NCT06256510
- Locations
- 🇧🇪
Pfizer Clinical Research Unit - Brussels, Brussels, Bruxelles-capitale, Région DE, Belgium
A Study to Determine the Effect of KP-001 on Metformin and Midazolam Pharmacokinetics and the Effect of Clarithromycin on KP-001 Pharmacokinetics in Healthy Adult Participants
- Conditions
- Interventions
- First Posted Date
- 2024-01-29
- Last Posted Date
- 2024-03-27
- Lead Sponsor
- Kaken Pharmaceutical
- Target Recruit Count
- 38
- Registration Number
- NCT06227832
- Locations
- 🇺🇸
Parexel Early Phase Clinical Unit - Los Angeles, Glendale, California, United States
Ketamine Treatment for PTSD and MDD in TBI
- Conditions
- Interventions
- First Posted Date
- 2024-01-29
- Last Posted Date
- 2024-01-29
- Lead Sponsor
- Minneapolis Veterans Affairs Medical Center
- Target Recruit Count
- 40
- Registration Number
- NCT06228391
- Locations
- 🇺🇸
Minneapolis VA Medical Center, Minneapolis, Minnesota, United States
Assessment of the Safety, Tolerability and Pharmacokinetics of AV078 in Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2024-01-16
- Last Posted Date
- 2024-11-27
- Lead Sponsor
- Aeovian Pharmaceuticals, Inc.
- Target Recruit Count
- 136
- Registration Number
- NCT06205381
- Locations
- 🇦🇺
Q-Pharm, Herston, Queensland, Australia
🇦🇺Nucleus Network Pty Ltd, Melbourne, Victoria, Australia
The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2024-01-12
- Last Posted Date
- 2024-01-12
- Lead Sponsor
- Siriraj Hospital
- Target Recruit Count
- 214
- Registration Number
- NCT06203405
- Locations
- 🇹🇭
Siriraj Hospital, Bangkok, Thailand
A Drug-Drug Interaction Study of Orforglipron (LY3502970) in Healthy Overweight and Obese Participants
- Conditions
- Interventions
- First Posted Date
- 2024-01-02
- Last Posted Date
- 2024-07-22
- Lead Sponsor
- Eli Lilly and Company
- Target Recruit Count
- 50
- Registration Number
- NCT06186622
- Locations
- 🇺🇸
Fortrea Clinical Research Unit Inc., Dallas, Texas, United States
Dexmedetomidine-ketamine Combination Versus Fentanyl-midazolam During Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2023-12-29
- Last Posted Date
- 2023-12-29
- Lead Sponsor
- University of Patras
- Target Recruit Count
- 50
- Registration Number
- NCT06185127
- Locations
- 🇬🇷
Naval Hospital, Athens, Attica, Greece
Use of Ketamine for Conscious Sedation in Flexible Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2023-12-26
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- Brooke Army Medical Center
- Target Recruit Count
- 66
- Registration Number
- NCT06181188
- Locations
- 🇺🇸
Brooke Army Medical Center, San Antonio, Texas, United States
Intranasal Dexmedetomidine Versus Intranasal Midazolam as a Premedication in Pediatrics Undergoing Upper GI Endoscopy
- First Posted Date
- 2023-12-26
- Last Posted Date
- 2023-12-26
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 70
- Registration Number
- NCT06181682
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.