Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Comparison in Frequency of Hypotension Between Remimazolam and Propofol in Hip Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-12-15
- Last Posted Date
- 2023-02-06
- Lead Sponsor
- Asan Medical Center
- Target Recruit Count
- 78
- Registration Number
- NCT05651399
- Locations
- 🇰🇷
Asan Medical Center, Seoul, Korea, Republic of
Effect of Remimazolam and Propofol on Hemodynamic Stability in Prone Position
- First Posted Date
- 2022-12-09
- Last Posted Date
- 2022-12-09
- Lead Sponsor
- Asan Medical Center
- Target Recruit Count
- 94
- Registration Number
- NCT05644483
- Locations
- 🇰🇷
Asan Medical Center, Seoul, Korea, Republic of
Esketamine-propofol Versus Propofol for Flexible Bronchoscopy
- Conditions
- Interventions
- First Posted Date
- 2022-12-08
- Last Posted Date
- 2024-01-05
- Lead Sponsor
- Fujian Provincial Hospital
- Target Recruit Count
- 246
- Registration Number
- NCT05643066
- Locations
- 🇨🇳
Fujian provincial hospital, Fuzhou, Fujian, China
Remimazolam Versus Propofol for Painless Abortion
- Conditions
- Interventions
- First Posted Date
- 2022-12-02
- Last Posted Date
- 2022-12-02
- Target Recruit Count
- 100
- Registration Number
- NCT05635955
- Locations
- 🇨🇳
Maternal and Child Health Hospital of Hubei Province, Wuhan, Hubei, China
Effect of Rematazolam Besylate, Propofol, and Sevoflurane Perioperative Sedation on Incidence of Emergence Agitation and Hemodynamics in Patients Undergoing Laparoscopic Abdominal Surgery
- First Posted Date
- 2022-11-22
- Last Posted Date
- 2022-11-22
- Target Recruit Count
- 1317
- Registration Number
- NCT05624424
- Locations
- 🇨🇳
Tumor Hospital of Jiangxi Province, Nanchang, Jiangxi, China
🇨🇳People's Hospital of Ganzhou, Ganzhou, Jiangxi, China
🇨🇳the First Affiliated Hospital of Gannan Medical College, Gannan Medical College, Ganzhou, Jiangxi, China
Cyclopol on Electrophysiological Monitoring During Spine Surgery: a Randomized Controlled, Noninferiority Study
- First Posted Date
- 2022-11-15
- Last Posted Date
- 2023-09-13
- Lead Sponsor
- Beijing Tiantan Hospital
- Target Recruit Count
- 148
- Registration Number
- NCT05617690
- Locations
- 🇨🇳
Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Dose-Finding and Human Abuse Potential Study Of HSK3486 Injection In Nondependent, Recreational Central Nervous System Depressant Users
- First Posted Date
- 2022-11-14
- Last Posted Date
- 2023-10-13
- Lead Sponsor
- Haisco-USA Pharmaceuticals, Inc.
- Target Recruit Count
- 42
- Registration Number
- NCT05614544
- Locations
- 🇺🇸
ICON (LPRA) - Salt Lake, Salt Lake City, Utah, United States
Influence of Sevoflurane and Propofol on Maximum Muscular Strength, Speed of Contraction and Relaxation
- Conditions
- Interventions
- First Posted Date
- 2022-11-14
- Last Posted Date
- 2023-07-10
- Lead Sponsor
- Brugmann University Hospital
- Target Recruit Count
- 48
- Registration Number
- NCT05615025
- Locations
- 🇧🇪
CHU Brugmann, Brussels, Belgium
RemImazolam Besylate for ICU-sedation in Patients With Mechanical Ventilation After Oral and Maxillofacial Surgery
- Conditions
- Interventions
- First Posted Date
- 2022-11-04
- Last Posted Date
- 2024-01-09
- Lead Sponsor
- Nanfang Hospital, Southern Medical University
- Target Recruit Count
- 285
- Registration Number
- NCT05606315
- Locations
- 🇨🇳
Peking University Shenzhen Hospital, Shenzhen, Guangdong, China
🇨🇳Southern medical university Nanfang hospital, Guangzhou, Guangdong, China
Ultrasound Guided Erector Spinae Block vs Thoracolumbar Interfascial Plane Block
- Conditions
- Interventions
- First Posted Date
- 2022-10-27
- Last Posted Date
- 2024-11-25
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 180
- Registration Number
- NCT05596227
- Locations
- 🇪🇬
Mona Mohamed Mogahed, Tanta, Elgharbia, Egypt
Drug Development Updates
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