Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. drowsiness, nausea, vomiting) than with thiopental, methohexital, and etomidate. Propofol may be used prior to diagnostic procedures requiring anaesthesia, in the management of refractory status epilepticus, and for induction and/or maintenance of anaesthesia prior to and during surgeries.
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
Comparison of Remimazolam and Propofol for Recovery of Ambulatory Upper Airway Surgery
- Conditions
- Laryngeal DiseaseOral Cavity DiseasePharyngeal DiseasesNasal Disease
- Interventions
- First Posted Date
- 2024-07-18
- Last Posted Date
- 2024-07-18
- Lead Sponsor
- Chung-Ang University Gwangmyeong Hospital
- Target Recruit Count
- 116
- Registration Number
- NCT06507202
- Locations
- 🇰🇷
ChungAng University Gwangmyeong Hospital, Gyeonggi-do, Gwangmyeon-si, Korea, Republic of
Additive Effects of Clonidine Used in Propofol Sedation in Colonoscopy
- Conditions
- PropofolClonidineSedationColonoscopy
- Interventions
- First Posted Date
- 2024-07-18
- Last Posted Date
- 2024-07-23
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 62
- Registration Number
- NCT06507410
- Locations
- 🇪🇬
Tanta University, Tanta, El-Gharbia, Egypt
Remimazolam Besylate and Propofol Sedation on Hemodynamic for Coronary Artery Bypass Graft Patients
- Conditions
- Coronary Artery Disease
- Interventions
- First Posted Date
- 2024-07-11
- Last Posted Date
- 2024-07-11
- Lead Sponsor
- Shanghai Zhongshan Hospital
- Target Recruit Count
- 338
- Registration Number
- NCT06496165
- Locations
- 🇨🇳
Zhongshan Hospital Fudan university, Shanghai, Shanghai, China
The Effects of Propofol and Thiopental on Nitric Oxide Production and Release in Erythrocytes
- First Posted Date
- 2024-07-03
- Last Posted Date
- 2024-08-01
- Lead Sponsor
- Melike Cengiz
- Target Recruit Count
- 12
- Registration Number
- NCT06485388
- Locations
- 🇹🇷
Akdeniz University School of Medicine, Department of Anesthesiology and Intensive Care, Turkey, Antalya, Turkey
Propofol vs. Nasal Dexmedetomidine in Pediatric Agitation and Delirium
- Conditions
- Comparison of the Effects of Propofol and Nasal Dexmedetomidine
- Interventions
- First Posted Date
- 2024-06-20
- Last Posted Date
- 2025-01-17
- Lead Sponsor
- Baskent University Ankara Hospital
- Target Recruit Count
- 162
- Registration Number
- NCT06466915
- Locations
- 🇹🇷
Ahmed Uslu, Ankara, Çankaya, Turkey
Patient-controlled Sedation With Propofol Versus Anesthesiologist-administered Sedation for Orthopedic Surgery
- Conditions
- Orthopedic Disorder
- Interventions
- Procedure: orthopaedic surgery
- First Posted Date
- 2024-06-11
- Last Posted Date
- 2025-03-27
- Lead Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
- Target Recruit Count
- 70
- Registration Number
- NCT06451380
- Locations
- 🇫🇷
Clinique Jouvenet, Paris, France
Use of Propofol as a Sedative Agent Versus Spinal Analgesia With Bupivacaine in External Cephalic Version
- Conditions
- Pregnancy Complications
- Interventions
- First Posted Date
- 2024-06-10
- Last Posted Date
- 2024-06-10
- Lead Sponsor
- Fundacion para la Formacion e Investigacion Sanitarias de la Region de Murcia
- Target Recruit Count
- 270
- Registration Number
- NCT06449430
- Locations
- 🇪🇸
Hospital Clínico Universitario Virgen de la Arrixaca, Murcia, Spain
Ciprofol Versus Propofol in Patients Undergoing Painless Hysteroscopy
- Conditions
- Painless Hysteroscopy
- Interventions
- First Posted Date
- 2024-05-14
- Last Posted Date
- 2024-08-07
- Lead Sponsor
- Baoding First Central Hospital
- Target Recruit Count
- 188
- Registration Number
- NCT06413862
Propofol Versus Dexmedetomidine for Sedation of Cancer Patients Undergoing ERCP
- First Posted Date
- 2024-05-10
- Last Posted Date
- 2024-05-14
- Lead Sponsor
- National Cancer Institute, Egypt
- Target Recruit Count
- 202
- Registration Number
- NCT06409104
- Locations
- 🇪🇬
Ahmed Mohamed Soliman, Giza, Egypt
Sevoflurane and Intravenous Anesthesia in Hypospadias Repair
- Conditions
- Intravenous AnesthesiaSevofluraneEmergence Delirium
- Interventions
- First Posted Date
- 2024-05-02
- Last Posted Date
- 2024-05-02
- Lead Sponsor
- Benha University
- Target Recruit Count
- 90
- Registration Number
- NCT06396468
- Locations
- 🇪🇬
Benha University, Banha, Egypt
Drug Development Updates
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