Propofol
- Generic Name
- Propofol
- Brand Names
- Diprivan
- Drug Type
- Small Molecule
- Chemical Formula
- C12H18O
- CAS Number
- 2078-54-8
- Unique Ingredient Identifier
- YI7VU623SF
- Background
Propofol is an intravenous anaesthetic agent used for induction and maintenance of general anaesthesia. IV administration of propfol is used to induce unconsciousness after which anaesthesia may be maintained using a combination of medications. Recovery from propofol-induced anaesthesia is generally rapid and associated with less frequent side effects (e.g. ...
- Indication
Used for induction and/or maintenance of anaesthesia and for management of refractory status epilepticus.
- Associated Conditions
- -
- Associated Therapies
- Induction of anesthesia therapy, Maintenance of anesthesia therapy, Monitored anesthesia care sedation, Sedative therapy
The Effects of the Anesthetic Drug Propofol on the Way the Heart Recovers Between Beats
- Conditions
- First Posted Date
- 2006-08-01
- Last Posted Date
- 2009-08-18
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 60
- Registration Number
- NCT00358618
- Locations
- 🇨🇦
British Columbia Children's Hospital, Anesthesia Dept., Vancouver, British Columbia, Canada
Renal Transplantation and Inhaled Anesthetic Sevoflurane (SEVOREIN)
- Conditions
- Interventions
- First Posted Date
- 2006-06-15
- Last Posted Date
- 2010-06-23
- Lead Sponsor
- University Hospital, Bordeaux
- Target Recruit Count
- 120
- Registration Number
- NCT00337051
- Locations
- 🇫🇷
Département d'anesthésie réanimation 1 - Hôpital Pellegrin - CHU de Bordeaux, Bordeaux, France
Anaesthesia With Propofol Versus Midazolam : Effect on Oxidative Stress in the Brain of Head Trauma Patients
- First Posted Date
- 2006-06-14
- Last Posted Date
- 2012-03-02
- Lead Sponsor
- Rennes University Hospital
- Target Recruit Count
- 30
- Registration Number
- NCT00336882
- Locations
- 🇫🇷
Réanimation Chirurgicale - Hôpital de Pontchaillou, Rennes, France
Effect of Dexmedetomidine Upon Sleep Postoperatively
- Conditions
- First Posted Date
- 2006-06-06
- Last Posted Date
- 2014-07-14
- Lead Sponsor
- Duke University
- Registration Number
- NCT00333632
- Locations
- 🇺🇸
Duke University Medical Center, Durham, North Carolina, United States
Effect Site Controlled, Reaction Time Safeguarded, Patient Maintained Sedation With Propofol in Healthy Volunteers
- Conditions
- First Posted Date
- 2006-05-03
- Last Posted Date
- 2012-02-07
- Lead Sponsor
- Sonia Allam
- Target Recruit Count
- 20
- Registration Number
- NCT00321360
- Locations
- 🇬🇧
Glasgow Dental Hospital, Glasgow, Strathclyde, United Kingdom
Post-Marketing Clinical Study to Assess Efficacy and Safety of Dexmedetomidine in Post-Operative Patients
- First Posted Date
- 2006-04-27
- Last Posted Date
- 2017-03-20
- Lead Sponsor
- Hospira, now a wholly owned subsidiary of Pfizer
- Target Recruit Count
- 85
- Registration Number
- NCT00318955
- Locations
- 🇯🇵
Kinki University Hospital, Osaka-Sayama-Shi, Osaka, Japan
🇯🇵Osaka University Hospital, Suita, Osaka, Japan
🇯🇵Nippon Medical School Hospital, Bunkyo-ku, Tokyo, Japan
The Influence of Injection Rate on EEG Propofol Peak Effect as Measured by Bispectral Index
- Conditions
- First Posted Date
- 2006-02-10
- Last Posted Date
- 2006-02-10
- Lead Sponsor
- Technical University of Munich
- Target Recruit Count
- 99
- Registration Number
- NCT00290108
- Locations
- 🇩🇪
Technische Universität München, Klinikum rechts der Isar, Department of Anesthesiology, Munich, Bavaria, Germany
Optimizing Propofol in Obese Patients
- First Posted Date
- 2005-12-26
- Last Posted Date
- 2009-10-16
- Lead Sponsor
- Rigshospitalet, Denmark
- Target Recruit Count
- 38
- Registration Number
- NCT00270335
- Locations
- 🇩🇰
Department of Anaesthesia, Copenhagen University Hospital Herlev, Herlev, Denmark
🇩🇰Department of Anaesthesia, Juliane Marie Centre, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark
Treatment of Refractory Status Epilepticus
- Conditions
- Interventions
- First Posted Date
- 2005-12-15
- Last Posted Date
- 2013-04-09
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 23
- Registration Number
- NCT00265616
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
🇨🇭Inselspital, Bern, BE, Switzerland
🇺🇸Massachusetts General Hospital, Boston, Massachusetts, United States
Propofol Injection for Daily Headache
- Conditions
- First Posted Date
- 2005-09-28
- Last Posted Date
- 2017-05-04
- Lead Sponsor
- University of Alberta
- Target Recruit Count
- 28
- Registration Number
- NCT00228267
- Locations
- 🇨🇦
Multidisciplinary Pain Centre, Univ. Alta Hospital, Edmonton, Alberta, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.