Cocaine
- Generic Name
- Cocaine
- Brand Names
- Goprelto, Numbrino
- Drug Type
- Small Molecule
- Chemical Formula
- C17H21NO4
- CAS Number
- 50-36-2
- Unique Ingredient Identifier
- I5Y540LHVR
- Background
An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechani...
- Indication
For the introduction of local (topical) anesthesia of accessible mucous membranes of the oral, laryngeal and nasal cavities.
- Associated Conditions
- -
- Associated Therapies
- -
n-Acetylcysteine and Cocaine
- Conditions
- Interventions
- First Posted Date
- 2014-05-19
- Last Posted Date
- 2017-01-04
- Lead Sponsor
- University of Kentucky
- Target Recruit Count
- 15
- Registration Number
- NCT02141620
- Locations
- 🇺🇸
University of Kentucky Laboratory of Human Behavioral Pharmacology, Lexington, Kentucky, United States
Impact of a Non-Drug Choice on Cocaine Reinforcement
- First Posted Date
- 2013-07-24
- Last Posted Date
- 2019-05-17
- Lead Sponsor
- Joshua A. Lile, Ph.D.
- Target Recruit Count
- 9
- Registration Number
- NCT01906346
- Locations
- 🇺🇸
Laboratory of Human Behavioral Pharmacology, Lexington, Kentucky, United States
Interactions Between Intravenous Cocaine and Acetazolamide or Quinine
- Conditions
- First Posted Date
- 2013-05-10
- Last Posted Date
- 2018-07-05
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 14
- Registration Number
- NCT01851473
- Locations
- 🇺🇸
National Institute on Drug Abuse, Baltimore, Maryland, United States
A Randomized, 4-sequence, 2-period, Double-blind, Placebo Controlled Study With a DSM-IV-TR Diagnosis of Cocaine Abuse
- Conditions
- Interventions
- First Posted Date
- 2013-05-03
- Last Posted Date
- 2016-09-23
- Lead Sponsor
- Indivior Inc.
- Target Recruit Count
- 40
- Registration Number
- NCT01846481
- Locations
- 🇺🇸
Vince and Associates Clinical Research, Overland Park,, Kansas, United States
Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery
- First Posted Date
- 2012-10-15
- Last Posted Date
- 2017-05-03
- Lead Sponsor
- Marc Tewfik
- Target Recruit Count
- 45
- Registration Number
- NCT01706952
- Locations
- 🇨🇦
Department of Otolaryngology-Head and Neck Surgery. McGill University Health Center, Montreal, Quebec, Canada
Intravitreal Injection Anesthesia - Comparison of Different Topical Agents
- Conditions
- Interventions
- First Posted Date
- 2010-10-20
- Last Posted Date
- 2012-04-19
- Lead Sponsor
- Lawson Health Research Institute
- Target Recruit Count
- 92
- Registration Number
- NCT01224847
- Locations
- 🇨🇦
Ivey Eye Institute, London, Ontario, Canada
Metabolic Effects of Cocaine
- Conditions
- First Posted Date
- 2007-03-23
- Last Posted Date
- 2017-01-18
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Target Recruit Count
- 15
- Registration Number
- NCT00451230
- Locations
- 🇺🇸
Massachusetts General Hospital, Boston, Massachusetts, United States
Effects of Vigabatrin on Cocaine Self-Administration
- First Posted Date
- 2006-09-08
- Last Posted Date
- 2016-10-27
- Lead Sponsor
- New York State Psychiatric Institute
- Target Recruit Count
- 1
- Registration Number
- NCT00373581
- Locations
- 🇺🇸
Irving Center for Clinical Research, New York, New York, United States
Human Dopamine Transported Imaging in Cocaine Abuse: 2 - 2
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000316
- Locations
- 🇺🇸
Johns Hopkins University, Baltimore, Maryland, United States
Stress Hormones and Human Cocaine Use - 7
- Conditions
- First Posted Date
- 1999-09-21
- Last Posted Date
- 2017-01-12
- Lead Sponsor
- National Institute on Drug Abuse (NIDA)
- Registration Number
- NCT00000290
- Locations
- 🇺🇸
University of Minnesota, Minneapolis, Minnesota, United States
Drug Development Updates
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