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Tetracaine

Generic Name
Tetracaine
Brand Names
Ametop, Cetacaine, Kovanaze, One Touch Reformulated Apr 2009, Pliaglis, Synera, Zap
Drug Type
Small Molecule
Chemical Formula
C15H24N2O2
CAS Number
94-24-6
Unique Ingredient Identifier
0619F35CGV
Background

Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.

Indication

Ophthalmic tetracaine is indicated for the for procedures requiring a rapid and short- acting topical ophthalmic anesthetic.

The combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.

Associated Conditions
Dermabrasion, Haemorrhoids, Insect Bites, Rash caused by poison ivy, Sunburn, Minor burns
Associated Therapies
Local Anaesthesia therapy, Local Anesthesia of the Skin
Clinical Trials
Related News

Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection

Early Phase 1
Active, not recruiting
Conditions
Intratympanic Steroid Injection
Idiopathic Sudden Sensorineural Hearing Loss
Meniere Disease
Interventions
First Posted Date
2021-03-12
Last Posted Date
2023-10-31
Lead Sponsor
Our Lady of the Lake Hospital
Target Recruit Count
80
Registration Number
NCT04794842
Locations
🇺🇸

Our Lady of the Lake Hospital, Baton Rouge, Louisiana, United States

Chloroprocaine 3% Gel Eye Drop as Topical Anestheticsin Phacoemulsification.

Phase 3
Completed
Conditions
Cataract
Interventions
First Posted Date
2020-12-28
Last Posted Date
2023-01-18
Lead Sponsor
Sintetica SA
Target Recruit Count
338
Registration Number
NCT04685538
Locations
🇮🇹

Policlinico S. Orsola-Malpighi - Dipartimento testa collo, U.O. Oftalmologia Ciardella, Bologna, Italy

🇮🇹

A.O.U. Careggi di Firenze - Dipartimento neuromuscoloscheletrico e organi di senso, reparto di oculistica, Firenze, Italy

🇮🇹

"IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano" - Dipartimento di chirurgia, U.O. Oculistica, Milano, Italy

and more 24 locations

Study to Determine the Effect of a Newly Formulated Tetracaine Product PET500 on Penile Skin Sensation

Phase 1
Completed
Conditions
Healthy Volunteers
Interventions
Other: Matching placebo (PET500)
Drug: STUD100
First Posted Date
2020-01-30
Last Posted Date
2020-01-30
Lead Sponsor
Futura Medical Developments Ltd.
Target Recruit Count
20
Registration Number
NCT04247230

Short Term Topical Tetracaine is Safe and Highly Efficacious for the Treatment of Pain Caused by Corneal Abrasions

Not Applicable
Completed
Conditions
Corneal Abrasion
Interventions
Drug: Placebo
First Posted Date
2019-12-05
Last Posted Date
2019-12-06
Lead Sponsor
INTEGRIS Southwest Medical Center
Target Recruit Count
118
Registration Number
NCT04187417

Pupil Centroid Shift Compensation in Photorefractive Keratectomy Candidates

Phase 2
Conditions
Pupil Centroid Shift
Interventions
Procedure: The option for compensation of Pupil centroid shift was ON
Procedure: The option for compensation of Pupil centroid shift was OFF
Procedure: Photorefractive keratectomy (PRK)
First Posted Date
2019-02-18
Last Posted Date
2019-02-18
Lead Sponsor
Shahid Beheshti University of Medical Sciences
Target Recruit Count
104
Registration Number
NCT03844178
Locations
🇮🇷

Ophthalmic Research Center, Tehran, Iran, Islamic Republic of

Ametop Compared to Ametop With Pain Ease Spray

Not Applicable
Conditions
Analgesia
Topical Anesthetic
Interventions
Device: Pain Ease Cold Spray
First Posted Date
2018-11-21
Last Posted Date
2018-11-21
Lead Sponsor
University of British Columbia
Target Recruit Count
240
Registration Number
NCT03749915
Locations
🇨🇦

BC Children's Hospital - Department of Anesthesia, Vancouver, British Columbia, Canada

Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment

Phase 4
Withdrawn
Conditions
Local Anesthesia
Endodontic Inflammation
Endodontic Disease
Dental Anesthesia
Interventions
First Posted Date
2018-04-18
Last Posted Date
2018-11-16
Lead Sponsor
University of North Carolina, Chapel Hill
Registration Number
NCT03502135

: Pulpal Blood Flow With the Use of Intra-nasal Anesthetic

Phase 4
Conditions
Local Anesthetic Drug Adverse Reaction
Local Infiltration
Pulp Disease, Dental
Interventions
Drug: saline intranasal
Drug: saline infiltration
First Posted Date
2017-12-11
Last Posted Date
2017-12-11
Lead Sponsor
Louisiana State University Health Sciences Center in New Orleans
Target Recruit Count
25
Registration Number
NCT03368391

Comparison Between 2% Lidocaine Gel and 5% Tetracaine Eye Drop as Topical Anesthesia in Phacoemulsification

Not Applicable
Completed
Conditions
Adult Patients Undergoing Phacoemulsification With Topical Anesthesia
Interventions
First Posted Date
2017-05-08
Last Posted Date
2018-02-28
Lead Sponsor
Indonesia University
Target Recruit Count
72
Registration Number
NCT03143452
Locations
🇮🇩

Cipto Mangunkusumo Central National Hospital, Jakarta, Indonesia

Neurobiological and Cognitive Changes Following Exposure to Either Sevoflurane- or Propofol-based Anesthesia in Children

Phase 3
Completed
Conditions
Cognitive Change
Behavior
Interventions
First Posted Date
2017-01-16
Last Posted Date
2020-03-26
Lead Sponsor
University of Calgary
Target Recruit Count
50
Registration Number
NCT03022240
Locations
🇨🇦

University of Calgary, Calgary, Alberta, Canada

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