Tetracaine
- Generic Name
- Tetracaine
- Brand Names
- Ametop, Cetacaine, Kovanaze, One Touch Reformulated Apr 2009, Pliaglis, Synera, Zap
- Drug Type
- Small Molecule
- Chemical Formula
- C15H24N2O2
- CAS Number
- 94-24-6
- Unique Ingredient Identifier
- 0619F35CGV
- Background
Tetracaine is an ester local anaesthetic currently available in combination with lidocaine as a cream and patch.
- Indication
Ophthalmic tetracaine is indicated for the for procedures requiring a rapid and short- acting topical ophthalmic anesthetic.
The combination lidocaine and tetracaine patch is indicated for local dermal analgesia for superficial dermatological procedures and superficial venous access. The combination lidocaine and tetracaine cream is intended to provide topical local analgesia for superficial dermatological procedures.
- Associated Conditions
- Dermabrasion, Haemorrhoids, Insect Bites, Rash caused by poison ivy, Sunburn, Minor burns
- Associated Therapies
- Local Anaesthesia therapy, Local Anesthesia of the Skin
Safety and Pharmacokinetics of Kovacaine Nasal Spray in Pediatric Subjects
- Conditions
- Anesthesia
- Interventions
- First Posted Date
- 2013-09-30
- Last Posted Date
- 2015-06-08
- Lead Sponsor
- St. Renatus, LLC
- Target Recruit Count
- 18
- Registration Number
- NCT01952990
- Locations
- 🇺🇸
AXIS Clinical Trials Research Center, Los Angeles, California, United States
Comparison of Two Topical Anesthetics: Benzocaine Versus Pliaglis
- Conditions
- Anesthesia of Mucous Membrane
- Interventions
- First Posted Date
- 2013-09-27
- Last Posted Date
- 2016-07-22
- Lead Sponsor
- University of Michigan
- Target Recruit Count
- 64
- Registration Number
- NCT01951820
- Locations
- 🇺🇸
University of Michigan Dental School, Ann Arbor, Michigan, United States
Efficacy of Ametop Cream in Reducing Pain of Local Anesthetic Infiltration
- First Posted Date
- 2013-05-29
- Last Posted Date
- 2013-12-11
- Lead Sponsor
- University of British Columbia
- Target Recruit Count
- 78
- Registration Number
- NCT01864213
- Locations
- 🇨🇦
BC Women's Hospital, Vancouver, British Columbia, Canada
Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Pediatric Patients
- Conditions
- Anesthesia
- Interventions
- Drug: Placebo
- First Posted Date
- 2013-05-01
- Last Posted Date
- 2017-08-30
- Lead Sponsor
- St. Renatus, LLC
- Target Recruit Count
- 90
- Registration Number
- NCT01844830
- Locations
- 🇺🇸
Big Grins, Fort Collins, Colorado, United States
🇺🇸Center for Dental Research Loma Linda University School, Loma Linda, California, United States
Safety and Pharmacokinetics of Kovacaine Nasal Spray (24 Hour Blood Collection)
- Conditions
- Anesthesia
- Interventions
- First Posted Date
- 2013-03-08
- Last Posted Date
- 2017-08-30
- Lead Sponsor
- St. Renatus, LLC
- Target Recruit Count
- 24
- Registration Number
- NCT01807624
- Locations
- 🇺🇸
Jean Brown Research, Salt Lake City, Utah, United States
Study of Use of Synera for Pain During Local Skin Infiltration With Lidocaine Before Epidural Placement
- First Posted Date
- 2013-01-25
- Last Posted Date
- 2015-05-14
- Lead Sponsor
- Northwell Health
- Registration Number
- NCT01775605
- Locations
- 🇺🇸
North Shore Unniversity Hospital, Manhasset, New York, United States
Comparison of Intranasal Kovacaine Mist, and Placebo for Anesthetizing Maxillary Teeth in Adults
- Conditions
- Anesthesia
- Interventions
- Drug: Placebo
- First Posted Date
- 2012-12-10
- Last Posted Date
- 2017-01-31
- Lead Sponsor
- St. Renatus, LLC
- Target Recruit Count
- 150
- Registration Number
- NCT01745380
- Locations
- 🇺🇸
Center for Dental Research Loma Linda University School, Loma Linda, California, United States
🇺🇸University of Maryland, Baltimore, Baltimore, Maryland, United States
🇺🇸University of Pennsylvania, School of Dental Medicine, Philadelphia, Pennsylvania, United States
Synera Venipuncture Pain
- Conditions
- PhlebotomyPainPalliative Care
- Interventions
- First Posted Date
- 2012-12-06
- Last Posted Date
- 2018-10-25
- Lead Sponsor
- US Oncology Research
- Target Recruit Count
- 61
- Registration Number
- NCT01744197
- Locations
- 🇺🇸
19 Locations Including, Dallas, Texas, United States
Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth in Adults
- Conditions
- Anesthesia
- Interventions
- First Posted Date
- 2012-10-19
- Last Posted Date
- 2017-08-30
- Lead Sponsor
- St. Renatus, LLC
- Target Recruit Count
- 110
- Registration Number
- NCT01710787
- Locations
- 🇺🇸
University of Buffalo, Buffalo, New York, United States
🇺🇸Jean Brown Research, Salt Lake City, Utah, United States
🇺🇸Family and Cosmetic Dentistry, Salt Lake City, Utah, United States
Comparison of Intranasal Kovacaine Mist, Tetracaine Alone, and Placebo for Anesthetizing Maxillary Teeth
- Conditions
- Anesthesia
- Interventions
- First Posted Date
- 2012-08-09
- Last Posted Date
- 2017-09-05
- Lead Sponsor
- St. Renatus, LLC
- Target Recruit Count
- 26
- Registration Number
- NCT01660893
- Locations
- 🇺🇸
University of Maryland, Baltimore, Baltimore, Maryland, United States
🇺🇸Jean Brown Research, Salt Lake City, Utah, United States
🇺🇸Family and Cosmetic Dentistry, Salt Lake City, Utah, United States
Drug Development Updates
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