Vinblastine

Generic Name
Vinblastine
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C46H58N4O9
CAS Number
865-21-4
Unique Ingredient Identifier
5V9KLZ54CY
Background

Antitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)

Indication

For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.

Associated Conditions
Advanced Soft Tissue Sarcoma, Autoimmune Hemolytic Anemia, Bladder Cancer, Hodgkin's Lymphoma, Immune Thrombocytopenia (ITP), Kaposi's Sarcoma, Letterer-Siwe disease, Metastatic Melanoma, Non-Small Cell Lung Cancer (NSCLC), Advanced Alibert-Bazin syndrome, Advanced Testicular cancer, Histiocytic lymphoma, Refractory Breast cancer
Associated Therapies
-

Radiation Therapy and Chemotherapy in Treating Patients With Hodgkin's Disease

First Posted Date
2003-11-21
Last Posted Date
2020-04-14
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
405
Registration Number
NCT00002561
Locations
🇨🇦

Regional Health Authority B, Zone 2, Saint John, New Brunswick, Canada

🇨🇦

Tom Baker Cancer Centre, Calgary, Alberta, Canada

🇬🇧

Royal South Hants Hospital, Southampton, United Kingdom

and more 19 locations

Cisplatin and Ifosfamide Combined With Either Paclitaxel or Vinblastine in Treating Men With Progressive or Recurrent Metastatic Germ Cell Tumors

First Posted Date
2003-11-06
Last Posted Date
2016-07-04
Lead Sponsor
Alliance for Clinical Trials in Oncology
Target Recruit Count
1
Registration Number
NCT00072215
Locations
🇺🇸

Broward General Medical Center, Fort Lauderdale, Florida, United States

🇺🇸

Memorial Cancer Institute at Memorial Regional Hospital, Hollywood, Florida, United States

🇺🇸

Palm Beach Cancer Institute - West Palm Beach, West Palm Beach, Florida, United States

and more 76 locations

S9901 Combination Chemotherapy With or Without Peripheral Stem Cell Transplantation in Treating Men With Stage III or Stage IV Hodgkin's Disease

First Posted Date
2003-08-28
Last Posted Date
2013-01-24
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
11
Registration Number
NCT00005090
Locations
🇺🇸

Memorial Sloan-Kettering Cancer Center, New York, New York, United States

🇺🇸

University of Chicago Cancer Research Center, Chicago, Illinois, United States

🇺🇸

University of Massachusetts Memorial Medical Center, Worcester, Massachusetts, United States

and more 44 locations

Combination Chemotherapy With or Without Interleukin-2 and Interferon Alfa in Treating Patients With Metastatic Melanoma

Phase 3
Completed
Conditions
First Posted Date
2003-01-27
Last Posted Date
2023-06-22
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
482
Registration Number
NCT00003027
Locations
🇺🇸

USC/Norris Comprehensive Cancer Center and Hospital, Los Angeles, California, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

🇺🇸

Veterans Affairs Medical Center - Chicago (Westside Hospital), Chicago, Illinois, United States

and more 91 locations

S0008: Chemotherapy Plus Biological Therapy in Treating Patients With Melanoma

First Posted Date
2003-01-27
Last Posted Date
2015-03-25
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
432
Registration Number
NCT00006237
Locations
🇺🇸

George Bray Cancer Center at the Hospital of Central Connecticut - New Britain Campus, New Britain, Connecticut, United States

🇺🇸

Mercy and Unity Cancer Center at Mercy Hospital, Coon Rapids, Minnesota, United States

🇺🇸

Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center, Columbus, Ohio, United States

and more 293 locations

Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Hodgkin's Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2023-06-29
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
854
Registration Number
NCT00003389
Locations
🇨🇦

Princess Margaret Hospital, Toronto, Ontario, Canada

🇺🇸

Piedmont Hospital, Atlanta, Georgia, United States

🇺🇸

Winship Cancer Institute of Emory University, Atlanta, Georgia, United States

and more 529 locations

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

First Posted Date
2003-01-27
Last Posted Date
2018-08-08
Lead Sponsor
Children's Hospital of Philadelphia
Target Recruit Count
23
Registration Number
NCT00030264
Locations
🇺🇸

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States

Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Lymphoma

First Posted Date
2003-01-27
Last Posted Date
2020-08-12
Lead Sponsor
Stanford University
Target Recruit Count
50
Registration Number
NCT00002715
Locations
🇺🇸

Stanford Cancer Center at Stanford University Medical Center, Stanford, California, United States

Chemotherapy With or Without Strontium-89 in Treating Patients With Prostate Cancer

First Posted Date
2003-01-27
Last Posted Date
2016-03-22
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
265
Registration Number
NCT00024167
Locations
🇺🇸

Siouxland Hematology-Oncology Associates, LLP, Sioux City, Iowa, United States

🇺🇸

St. Luke's Regional Medical Center, Sioux City, Iowa, United States

🇺🇸

University of Mississippi Cancer Clinic, Jackson, Mississippi, United States

and more 36 locations
© Copyright 2024. All Rights Reserved by MedPath