Trimetazidine
- Generic Name
- Trimetazidine
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C14H22N2O3
- CAS Number
- 5011-34-7
- Unique Ingredient Identifier
- N9A0A0R9S8
- Background
Trimetazidine is a piperazine derivative indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies. Trimetazidine has been studied as a treatment for angina pectoris since the late 1960s.
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- Indication
Trimetazidine is indicated for the symptomatic treatment of stable angina pectoris in patients inadequately controlled or intolerant to first line therapies.
- Associated Conditions
- Angina Pectoris, Chronic Stable Angina Pectoris, Tinnitus, Vertigo, Decreased visual acuity caused by Vascular Disorders
- Associated Therapies
- -
Cardiac Metabolic Modulator Treatment for Improvement of Diastolic Function in Patients With Coronary Heart Disease
- First Posted Date
- 2019-03-22
- Last Posted Date
- 2019-03-25
- Target Recruit Count
- 226
- Registration Number
- NCT03887013
- Locations
- 🇨🇳
Fuwai Hospital, Chinese Academy of Medical Sciences, National Center for Cardiovascular Diseases, Beijing, Beijing, China
Effects of Yangxinshi Pills on the Exercise Tolerance Compared With Trimetazidine in Patients After PCI
- Conditions
- Interventions
- First Posted Date
- 2019-01-18
- Last Posted Date
- 2020-10-19
- Lead Sponsor
- Shenyang Northern Hospital
- Target Recruit Count
- 668
- Registration Number
- NCT03809273
- Locations
- 🇨🇳
Beijing Anzhen Hospital, Capital Medical University, Beijing, Beijing, China
🇨🇳The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, China
🇨🇳Hebei General Hospital, Shijiazhuang, Hebei, China
TRimetazidine for acUte on Chronic Liver Failure STudy
- First Posted Date
- 2018-11-09
- Last Posted Date
- 2021-03-04
- Lead Sponsor
- Martin Pharmaceuticals
- Target Recruit Count
- 30
- Registration Number
- NCT03737448
- Locations
- 🇧🇪
Erasme Hospital, Brussels, Belgium
🇫🇷Hospital Claude Huriez, Lille, France
🇫🇷Rennes University Hospital, Rennes, France
Trimetazidine in Myocardial Injury After Percutaneous Coronary Intervention in Patients With Angina and Diabetes
- Conditions
- Interventions
- First Posted Date
- 2018-10-23
- Last Posted Date
- 2018-10-24
- Lead Sponsor
- University of Sao Paulo General Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT03715582
- Locations
- 🇧🇷
Instituto do Coração - HMFMUSP, São Paulo, Brazil
Trimetazidine as an Adjunct to Enhance Clopidogrel Response.
- First Posted Date
- 2018-07-27
- Last Posted Date
- 2019-12-02
- Lead Sponsor
- The University of The West Indies
- Target Recruit Count
- 24
- Registration Number
- NCT03603249
- Locations
- 🇹🇹
The University of the West Indies, Saint Augustine, North, Trinidad and Tobago
Effect of Trimetazidine on the Improvement of Coronary Microvascular Dysfunction in Patients With INOCA(Ischemia and no Obstructive Coronary Artery Disease)
- Conditions
- Interventions
- First Posted Date
- 2018-04-20
- Last Posted Date
- 2018-10-25
- Lead Sponsor
- Shanghai 10th People's Hospital
- Target Recruit Count
- 10
- Registration Number
- NCT03504202
The Role of Trimetazidine on Right Ventricle Function in Pulmonary Arterial Hypertension
- Conditions
- Interventions
- First Posted Date
- 2017-09-06
- Last Posted Date
- 2019-10-03
- Lead Sponsor
- Indonesia University
- Target Recruit Count
- 26
- Registration Number
- NCT03273387
- Locations
- 🇮🇩
National Cardiovascular Center Harapan Kita Hospital, Jakarta, Indonesia
Effect of Trimetazidine During the Primary PCI on Cardiac Function in Patients With ST-elevation Myocardial Infarction
- First Posted Date
- 2016-07-11
- Last Posted Date
- 2016-07-11
- Lead Sponsor
- Chinese PLA General Hospital
- Target Recruit Count
- 240
- Registration Number
- NCT02826616
- Locations
- 🇨🇳
Chinese People's Liberation Army General Hospital, Peking, Beijing, China
The ImPact of Trimetazidine on MicrOcirculation After Stenting for Stable Coronary Artery Disease
- Conditions
- Interventions
- First Posted Date
- 2014-04-08
- Last Posted Date
- 2023-06-02
- Lead Sponsor
- Clinical Hospital Center Zemun
- Target Recruit Count
- 71
- Registration Number
- NCT02107144
- Locations
- 🇷🇸
Institute for cardiovascular diseases Dedinje, Belgrade, Serbia
Trimetazidine in Pulmonary Artery Hypertension
- First Posted Date
- 2014-04-03
- Last Posted Date
- 2014-04-03
- Lead Sponsor
- Pontificia Universidad Catolica de Chile
- Target Recruit Count
- 25
- Registration Number
- NCT02102672
- Locations
- 🇨🇱
Hospital Clinico Pontificia Universidad Catolica de Chile, Santiago, Metropolitana, Chile
Drug Development Updates
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